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Aldose Reductase Inhibitory Activity of Scrophularia Species  

Kim, Hye-Min (Department of Applied Plant Science, Chung-Ang University)
Han, Saem (Department of Applied Plant Science, Chung-Ang University)
Lee, Yeon-Sil (Center for Efficacy Assessment and Development of Functional Foods and Drugs, Hallym University)
Chung, Jae-Min (Department of Plant Resources Conservation, Korea National Arboretum)
Lee, Sang-Hyun (Department of Applied Plant Science, Chung-Ang University)
Publication Information
Natural Product Sciences / v.16, no.1, 2010 , pp. 54-57 More about this Journal
Abstract
Effects of the species Scrophularia takesimensis, S. kakudensis, S. boreali-koreana, and S. buergeriana on rat lens aldose reductase inhibition have been investigated. Among them, the extracts of S. kakudensis and S. boreali-koreana were exhibited good inhibitory potencies compared with those of S. takesimensis and S. buergeriana. The $IC_{50}$ values of the aerial part extracts from S. kakudensis and S. boreali-koreana were demonstrated 0.46 and 0.35 mg/ml, respectively.
Keywords
Scrophularia species; rat lens aldose reductase; diabetic complications;
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Times Cited By KSCI : 3  (Citation Analysis)
Times Cited By SCOPUS : 1
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