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Phytochemical Constituents of Amomum xanthioides  

Choi, Jung-Wook (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University)
Kim, Ki-Hyun (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University)
Lee, Il-Kyun (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University)
Choi, Sang-Un (Korea Research Institute of Chemical Technology)
Lee, Kang-Ro (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University)
Publication Information
Natural Product Sciences / v.15, no.1, 2009 , pp. 44-49 More about this Journal
Abstract
Seven monoterpenes, three sesquiterpenes, three phenolics and one flavonoid were isolated from the MeOH extract of Amomum xanthioides. Their structures were determined by spectroscopic methods to be caryophyllene oxide (1), bornyl acetate (2), nerolidol (3), spathulenol (4), (-)-borneol (5), (+)-5-endohydroxycamphor (6), vanillic acid (7), protocatechuic acid methyl ester (8), betulabuside A (9), (1R,4S,6R)-6-hydroxyfenchan-2-one-6-O-$\beta$-D-glucopyranoside (10), (1S,4R,6S)-6-hydroxybornan-2-one-6-O-$\beta$-D-glucopyranoside (11), (1R,2S,4S,5R)-angelicoidenol 2-O-$\beta$-D-glucopyranoside (12), 1-O-vanilloyl-$\beta$-D-glucopyranoside (13), and quercetin-3-rhamnopyranoside (14). Compounds 6-14 were isolated for the first time from this plant source. Compounds 3 and 4 exhibited moderate cytotoxicity against four human cancer cell lines in vitro using a SRB bioassay.
Keywords
Amomum xanthioides; Zingiberaceae; Monoterpenes; Sesquiterpenes; Cytotoxicity;
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