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Microbial Transformation of Isoxanthohumol, a Hop Prenylflavonoid  

Kim, Hyun-Jung (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
Kang, Min-Ah (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
Lee, Ik-Soo (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
Publication Information
Natural Product Sciences / v.14, no.4, 2008 , pp. 269-273 More about this Journal
Abstract
Microbial transformation of isoxanthohumol (1), a prenylated flavanone from hops, has resulted in the production of a pair of glucosylated derivatives. The structures of these compounds were elucidated to be (2S)-5-methoxy-8-prenylnaringenin 7-O-${\beta}$-D-glucopyranoside (2) and (2R)-5-methoxy-8-prenylnaringenin 7-O-${\beta}$-Dglucopyranoside (3) based on the spectroscopic analyses.
Keywords
Microbial transformation; hop prenylflavonoid; isoxanthohumol; 5-methoxy-8-prenylnaringenin 7-O-${\beta}$-D-glucopyranoside;
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