Mangiferin isolated from the rhizome of Anemarrhena asphodeloides inhibits the LPS-induced nitric oxide and prostagladin via the inactivation in inflammatory macrophages |
Shin, Ji-Sun
(College of Pharmacy, Kyung Hee University)
Noh, Young-Su (College of Pharmacy, Kyung Hee University) Kim, Dong-Hyun (College of Pharmacy, Kyung Hee University) Cho, Young-Wuk (College of Medical science, Kyung Hee University) Lee, Kyung-Tae (College of Pharmacy, Kyung Hee University) |
1 | Aritomi, M. and Kawasaki, T., A new xanthone C-glucoside, position isomer of mangiferin, from Anemarrhena asphodeloides bunge. Tetraahedron. Lett. 12, 941-944 (1969) |
2 | Butler, D., Maini, R.N., Feldmann, M., and Brennan, F.M., Blockade of TNF with chimeric anti TNF monoclonal antbody, cA2 reduces (IL-6 and IL-8) release in RANMC culcures: a comparison with IL-1ra. Eur. Cytokine Netw. 6, 225-230 (1995) PUBMED |
3 | Elenkov, I.J. and Chriusos, G.P., Stress hormones, proinflammatory and anti-inflammatory cytokines, and autoimmunity. Ann. NY. Acad. Sci. 966, 290-303 (2002) DOI ScienceOn |
4 | Feldmann, M., Brennan, F.M., and Maini, R.N., Role of cytokines in rheumatoid arthritis. Annu. Rev. Immunol. 14, 397-440 (1996) DOI ScienceOn |
5 | Guha, M. and Mackman, N., LPS induction of gene expression in human monocytes. Cell Signal. 13, 85-94 (2001) DOI ScienceOn |
6 | Librowski, T., Czarnecki, R., Czekai, T., and Marona, H., New xanthone derivatives as potent anti-inflammatory agents. Medicina (Kaunas). 41, 54-58 (2005) PUBMED |
7 | Lin, C.N., Chung, M.I., Liou, S.J., Lee, T.H., and Wang, J.P., Synthesis and Anti inflamm atory Effects of Xanthone Derivatives. J. Pharm. Pharmacol. 48, 532-538 (1996) DOI ScienceOn |
8 | Lin, Y.L. and Lin, J.K., (−)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Mol. Pharmacol. 52, 465-472 (1997) DOI PUBMED |
9 | Molloy, R.G., Mannick, J.A., and Rodrick, M.L., Cytokines, sepsis and immunomodulation. Br. J. Surg. 80, 289-297 (1993) DOI ScienceOn |
10 | Moreira, R.R., Carlos, I.Z., and Vilega, W., Release of intermediate reactive hydrogen peroxide by macrophage cells activated by natural products. Biol. Pharm. Bull. 24, 201-204 (2001) DOI ScienceOn |
11 | Shin, K.M., Kim, I.T., Park, Y.M., Ha, J., Choi, J.W., Park, H.J., Lee, Y.S., and Lee, K.T., Anti-inflammatory effect of caffeic acid methyl ester and its mode of action through the inhibition of prostaglandin E2, nitric oxide and tumor necrosis factor-alpha production. Biochem. Pharmacol. 68, 2327-2336 (2004) DOI ScienceOn |
12 | Simon, L.S., Role of regulation of cyclooxygenase-2 during inflammation. Am. J. Med. 106, 37S-42S (1999) DOI ScienceOn |
13 | Song, Y.S., Park, E.H., Hur, G.M., Ryu, Y.S., Lee, Y.S., Kim, Y.M., and Jin, C., Caffeic acid phenethyl ester inhibits nitric oxides synthase gene expression and enzyme activity. Cancer. Lett. 175, 53-61 (2002) DOI ScienceOn |
14 | Xiong, O., Tezuka, Y., Kaneko, T., Li, H., Tran, L.Q., Hase, K., Namba, T., and Kadota, T., Inhibition of nitric oxide by phenylethanoids in activated macrophages. Eur. J. Pharmacol. 14, 137-144 (2000) |
15 | Vane, J.R., Mitchell, J.A., Appleton, I., Tomlinson, A., Bishop-bailey, D., Croxtall, J., and Willoughby, D.A., Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Pharmacology. 91, 2046-2050 (1994) |
16 | Nemeth, J.F., Hochgesang, G.P. Jr., Marnett, L.J., and Caprioli, R.M., Characterization of the Glycosylation Sites in Cyclooxygenase-2 Using Mass Spectrometry. Biochemistry. 40, 3109-3116 (2001) DOI ScienceOn |
17 | Bredt, D.S. and Snyder, S.H., Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc Natl. Acad. Sci. 87, 682-685 (1990) |
18 | Forman, H.J. and Torres, M., Redox signaling in macrophages. Mol. Aspects. Med. 22, 189-216 (2001) DOI ScienceOn |
19 | Ichiki, H., Miura, T., Kubo, M., Ishihara, E., Komatsu, Y., Tanigawa K., and Okada, M., New antidiabetic compounds, mangiferin and its glucoside. Biol. Pharm. Bull. 21, 1389-1390 (1998) DOI PUBMED ScienceOn |
20 | Chen, Y., Yang, T.J., and Oroxylin, L., A inhibition of lipopolysaccharideinduced iNOS and COX-2 gene expression via suppression of nuclear factor-kappaB activation. Biochem. Pharmacol. 59, 1445-1457 (2000) DOI ScienceOn |
21 | Mannel, D.N. and Echtenacher, B., TNF in the inflammatory response. Chem. Immunol. 74, 141-161 (2000) PUBMED |
22 | Virgili, F., Kobuchi, H., and Packer, L., Procyanidins extracted from Pinus maritima (Pycnogenol): scavengers of free radical species and modulators of nitrogen monoxide metabolism in activated murine RAW264.7 macrophages. Free. Radic. Biol. Med. 24, 1120-1129 (1998) DOI ScienceOn |
23 | Funk, C.D., Funk, L.B., Kennedy, M.E., Pong, A.S., and Fittzgerald, G.A., Human Platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression and gene chromosomal assignment. FASEB J. 5, 2304-2312 (1991) DOI PUBMED |
24 | Hla, T. and Neilson, K., Human Cyclooxygenase-2 cDNA. Proc. Natl. Acad. Sci. U. S. A. 89, 7384-7388 (1992) |
25 | Guha, S., Ghosal, S., and Chattopadhyay, U., Antitumor, immunomodulatory and anti-HIV effect of mangiferin, a naturally occurring glucosylxanthone. Chemotherapy. 42, 443-451 (1996) DOI ScienceOn |
26 | Tsai, S.H., Lin-Shiau, S.Y., and Lin, J.K., Suppression of nitric oxide synthase and the down-regulation of the activation of in macrophages by resveratrol. Br. J. Pharmacol. 112, 673-680 (1999) |
27 | Haworth, C., Brennan, F.M., Chantry, D., Tunner, M., Maini, R. N., and Feldmann, M., Expression of granulocyte-macrophage colonystimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-a. Eur. J. Immunol. 21, 2575-2579 (1991) DOI ScienceOn |
28 | Jang, B.C., Sung, S.H., Park, J.G., Park, J.W., Bae, J.H., Shin, D.H., Park, G.Y., Han, S.B., and Suh, S.I., Glucosamine hydrochloride specifically inhibits COX-2 by preventing COX-2 N-glycosylation and by increasing COX-2 protein turnover in a proteasome-dependent manner. J. Biol. Chem. 282, 27622-27632 (2007) DOI ScienceOn |
29 | Jun, C.D., Choi, B.M., Kim, H.M., and Chung, H.T., Involvement of protein kinase C during taxol-induced activation of murine peritoneal macrophages. J. Immunol. 154, 6541-6547 (1995) PUBMED |
30 | Madan, B., Prasad, A.K., Parmar, V.S., and Ghosh, B., 1,4- dihydroxyxanthone modulates the adhesive property of endothelial cells by inhibiting intercellular adhesion mole cule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin. Bioorg. Med. Chem. 12, 1431-1437 (2004) DOI ScienceOn |
31 | Sanchez, G.M., Re, L., Giuliani, A., Nunez-Selles, A.J., Davison G.P., and Leon-Fernández, O.S., Protective effects of Mangifera indica L. extract, mangiferin and selected antioxidants against TPA-induced biomolecules oxidation and peritoneal macrophage activation in mice. Pharmacol. Res. 42, 565-573 (2000) DOI ScienceOn |
32 | Perkins, D.J. and Kniss, D.A., Blockade of nitric oxide formation downregulates cyclo oxygenase-2 and decreases biosynthesis in macrophages. J. Leukoc. Biol. 65, 792-799 (1999) DOI PUBMED |
33 | Surh, Y.J., Chun, K.S., Cha, H.H., Han, S.S., Keum, Y.S., Park, K.K., and Lee, S.S., Molecular mechanism underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat. Res. 1, 243-268 (2001) |
34 | Lappas, M., Permezel, M., Georgiou, H.M., and Rice, G.E., Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro. Biol Reprod. 67, 668-673 (2002) DOI ScienceOn |
35 | Yamakuni, T., Aoki, K., Nakatani, K., Kondo, N., Oku, H., Ishiguro, K., and Ohizumi, Y., Garcinone B reduces prostaglandin E2 release and NF-kappaB-mediated transcription in C6 rat glioma cells. Neurosci. Lett. 394, 206-210 (2006) DOI ScienceOn |
36 | Leiro, J., Arranz, J.A., Yáñez, M., Ubeira, F.M., Sanmartín, M.L., and Orallo, F., Expression profiles of genes involved in the mouse nuclear factor-kappa B signal transduction pathway are modulated by mangiferin. Int. Immunopharmacol. 4, 763-478 (2004) DOI ScienceOn |
37 | Yoshimi, N., Matsunaga, K., Katayma, M., Yamada, Y., Kuno, T., Qiao, Z., Hara, A., Yamahara, J., and Mori, H., The inhibitory effects of mangiferin, a naturally occurring glucosylxanthone, in bowel carcinogenesis of male F344 rats. Cancer. Lett. 163 163-170 (2001) DOI ScienceOn |
38 | Luceri, C., Caderni, G., Sanna, A., and Dolara, P., Red wine and black tea polyphenols modulate the expression of cycloxygenase-2, inducible nitric oxide synthase and glutathione-related enzymes in azoxymethane-induced f344 rat colon tumors. J. Nutr. 132, 1376-1379 (2002) |
39 | Nathan, C. and Xie, Q.W., Nitric oxide synthase: roles, tolls and control. Cell. 78, 915-918 (1994) DOI ScienceOn |
40 | Hinz B. and Brune K., Cyclooxygenase-2-10 years later. J. Pharmacol. Exp. Ther. 300, 367-375 (2002) DOI ScienceOn |