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Polyacetylenes from the Tissue Cultured Adventitious Roots of Panax ginseng C.A. Meyer  

Xu, Guang-Hua (Functional Metabolite Research Center, Korea Research Institute of Bioscience and Biotechnology)
Choo, Soo-Jin (Functional Metabolite Research Center, Korea Research Institute of Bioscience and Biotechnology)
Ryoo, In-Ja (Functional Metabolite Research Center, Korea Research Institute of Bioscience and Biotechnology)
Kim, Young-Hee (Functional Metabolite Research Center, Korea Research Institute of Bioscience and Biotechnology)
Paek, Kee-Yoeup (Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University)
Yoo, Ick-Dong (Functional Metabolite Research Center, Korea Research Institute of Bioscience and Biotechnology)
Publication Information
Natural Product Sciences / v.14, no.3, 2008 , pp. 177-181 More about this Journal
Abstract
Five polyacetylenes, ginsenoyne K (1), (Z)-1-methoxyheptadeca-9-en-4,6-diyne-3-one (2), panaxydol (3), panaxydiol (4), and (E)-heptadeca-8-en-4,6-diyne-3,10-diol (5) were isolated from the adventitious roots of Panax ginseng and their chemical structurFive polyacetylenes, ginsenoyne K (1), (Z)-1-methoxyheptadeca-9-en-4,6-diyne-3-one (2), panaxydol (3), panaxydiol (4), and (E)-heptadeca-8-en-4,6-diyne-3,10-diol (5) were isolated from the adventitious roots of Panax ginseng and their chemical structures were elucidated by interpretation of spectroscopic data. Among the isolated compounds, compounds 2 and 5 were reported for the first time as a natural product. Ginsenoyne K (1) showed dose-dependent inhibitory effect on dopa oxidase activity of tyrosinase.es were elucidated by interpretation of spectroscopic data. Among the isolated compounds, compounds 2 and 5 were reported for the first time as a natural product. Ginsenoyne K (1) showed dose-dependent inhibitory effect on dopa oxidase activity of tyrosinase.
Keywords
Panax ginseng; polyacetylenes; tyrosinase;
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