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Cytotoxic and Antibacterial Activities of Gossypin  

Chamundeeswari, D. (Sri Ramachandra College of Pharmacy, Sri Ramachandra University)
Sukumar, Ethirajan (Department of Applied Sciences, Higher College of Technology)
Amar, K. (Sri Ramachandra College of Pharmacy, Sri Ramachandra University)
Reddy, N. Brahmananda (Sri Ramachandra College of Pharmacy, Sri Ramachandra University)
Kumar, I. Anil (Sri Ramachandra College of Pharmacy, Sri Ramachandra University)
Chowdry, B.V. (Sri Ramachandra College of Pharmacy, Sri Ramachandra University)
Samatha, K. (Sri Ramachandra College of Pharmacy, Sri Ramachandra University)
Publication Information
Natural Product Sciences / v.13, no.4, 2007 , pp. 300-303 More about this Journal
Abstract
Gossypin, a naturally occurring polyhydroxy flavonoid, when subjected to in vitro cytotoxic screening against vero cell lines exhibited 68.75% inhibition at a concentration of $1000{\mu}g$. When tested against five bacteria and five fungi, the flavone derivative showed a moderate activity against Staphylococcus aureus and Escherichia coli, mild inhibition against Pseudomonas aerugenosa and Salmonella typhi and no activity against any of the tested fungi, in the concentrations studied.
Keywords
Gossypin; cytotoxicity; antibacterial activity;
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