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Trisoxazole Macrolide from a Marine Sponge Sarcotragus Species  

Liu, Yong-Hong (College of Pharmacy, Pusan National University)
Shinde, Pramod B. (College of Pharmacy, Pusan National University)
Hong, Jong-Ki (Hazardous Substance Research Team, Korea Basic Science Institute)
Lee, Chong-O. (Pharmaceutical Screening Center, Korea Research Institute of Chemical Technology)
Im, Kwang-Sik (College of Pharmacy, Pusan National University)
Jung, Jee-H. (College of Pharmacy, Pusan National University)
Publication Information
Natural Product Sciences / v.11, no.1, 2005 , pp. 50-53 More about this Journal
Abstract
Bioassay-directed fractionation of the lipophilic extract of a marine sponge Sarcotragus sp. led to the isolation of a known trisoxazole containing macrolide, mycalolide B (1). Its structure was identified by NMR and MS analyses. This is the first report on the isolation of macrolide from a sponge of the genus Sarcotragus (Order: Dictyoceratida).
Keywords
Sarcotragus; macrolide; mycalolide B; sponge; spectroscopy;
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