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Antioxidant Effects of Plant Extracts on Free Radicals and Lipid Peroxidation  

Na, Min-Kyun (College of Pharmacy, Chungnam National University, Jakwang Research Institute, HanKookSinYak Co., Ltd.)
An, Ren-Bo (Korea Research Institute of Bioscience and Biotechnology, College of Pharmacy, Yanbian University)
Jin, Wen-Yi (College of Pharmacy, Chungnam National University, College of Pharmacy, Yanbian University)
Min, Byung-Sun (Korea Research Institute of Bioscience and Biotechnology)
Yoo, Jae-Kuk (College of Pharmacy, Chungnam National University, Jakwang Research Institute, HanKookSinYak Co., Ltd.)
Kim, Young-Ho (College of Pharmacy, Chungnam National University)
Bae, Ki-Hwan (College of Pharmacy, Chungnam National University)
Publication Information
Natural Product Sciences / v.9, no.4, 2003 , pp. 226-231 More about this Journal
Abstract
Reactive oxygen species damage biomolecules such as lipids, proteins, sugars and DNA, which can not only lead to various disease but also oxidative damage resulting aging. In order to search for antioxidants from plants, the antioxidant effects of the MeOH extracts from 182 plants were evaluated. The results showed that thirteen plant extracts exhibited antioxidant activity (>80%) in DPPH radical assay, seven plant extracts demonstrated antioxidant activity (>40%) in the hydroxyl radical assay and eighteen plant extracts were active (>80%) in the lipid peroxidation assay. In particular, the extracts of Distylium racemosum (Hamamelidaceae), Astilbe koreana (Saxifragaceae), Astilbe chinensis and Euphorbia supina (Euphorbiaceae) were identified as potent principles of antioxidant activity in all the assay systems.
Keywords
Antioxidant; Distylium racemosum; Astilbe koreana; Astilbe chinensis; Euphorbia supina;
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Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By SCOPUS : 14
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