Browse > Article

A New Cyclitol Derivative from a Sponge Stelletta Species  

Zhao, Qingchun (College of Pharmacy, Pusan National University, Shenyang Northern Hospital)
Liu, Yong-Hong (College of Pharmacy, Pusan National University)
Hong, Jong-Ki (Korea Basic Science Institute)
Lee, Chong-O. (Korea Research Institute of Chemical Technology)
Park, Jong-Hee (College of Pharmacy, Pusan National University)
Lee, Dong-Seok (Department of Biomedical Science and Engineering, Inje University)
Jung, Jee-H. (College of Pharmacy, Pusan National University)
Publication Information
Natural Product Sciences / v.9, no.1, 2003 , pp. 18-21 More about this Journal
Abstract
Guided by the brine shrimp lethality assay, a new (4) and three known cyclitol derivatives (1-3) were isolated from the marine sponge Stelletta sp. Norsarcotride A (4) showed significant cytotoxicity against a small panel of five human tumor cell lines.
Keywords
Stelletta sp.; cyclitol derivative; cytotoxicity; marine sponge;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By SCOPUS : 3
연도 인용수 순위
1 Costantino, V., Fattorusso, E., and Mangoni, A., The stereochemistry of crasserides. J. Nat. Prod. 57, 1726-1730 (1994)   DOI   ScienceOn
2 Liu, Y., Lee, C.-O., Hong, J., and Jung, J. H., Cyclitol derivatives from the sponge Sarcotragus species. Bull. Korean Chem. Soc. 23, 1467-1469 (2002)   DOI
3 Shin, J., Seo, Y., Cho, K. W., Rho, J.-R., and Sim, C. J., Stellettamide B, a new indolizidine alkaloid from a sponge of the genus Stelleta. J. Nat. Prod. 60, 611-613 (1997)   DOI   ScienceOn
4 Tsukamoto, S., Yamashita, T., Matsunaga, S., and Fusetani, N., Bistellettadines A and B: two bioactive dimeric stellettadines from a marine sponge Stelletta sp. J. Org. Chem. 64, 3794-3795 (1999a)   DOI   ScienceOn
5 Tsukamoto, S., Kato, H., Hirota, H., and Fusetaui, N., Stellettadine A: a new acylated bisguanidium alkaloid which induces larval metamorphosis in ascidians from a marine sponge Stelletta sp. Tetrahedron Lett. 37, 5555-5556 (1996)   DOI   ScienceOn
6 Ryu, G., Matsunaga, S., and Fusetani, N., Globostellatic acids A-D, new cytotoxic isomalabricane triterpenes from the marine sponge Stelletta globostellata. J. Nat. Prod. 59, 512-514 (1996)   DOI   ScienceOn
7 Kobayashi, J., Zeng, C. M., and Ishibashi, M., Keruffaride, a new all-cis cyclopentanepentol-containing metabolite from the Okinawan marine sponge Luffariella sp. J. Chem. Soc., Chem. Commun. 79-81 (1993)
8 Miyamoto, T., Kodama, K., Aramaki, Y., Higuchi, R., and Van Soest, R, W, M., Orostanal, a novel abeo-sterol inducing apoptosis in leukemia cell from a marine sponge, Stelletta hiwasaensis. Tetrahedron Lett. 42, 6349-6351 (2002)   DOI   ScienceOn
9 McCabe, T., Clardy, J., Minale, L., Pizza, C., Zollo, F., and Riccio, R., A triterpenoid pigment with the isomalabricane skeleton from the marine sponge Stelletta sp. Tetrahedron Lett. 23, 3307-3310 (1982)   DOI   ScienceOn
10 McCormick. J. L.. McKee. T. C., Cardellina. J. H., Leid. M., and Boyd, M. R., Cytotoxic triterpenes from a marine sponge, Stelleta sp. J. Nat. Prod. 59, 1047-1050 (1996)   DOI   ScienceOn
11 Li, H., Matsunaga, S., and Fusetani, N., Bioactive marine metabolites. 62. A new 9,11-secosterol, stellettasterol from a marine sponge Stelletta sp. Experientia 50, 771-773 (1994)   DOI   ScienceOn
12 Guerriero, A., Debitus, C., and Pietra, F., On the first marine stigmastane sterols and sterones having a 24,25-double bond. Isolation from the sponge Stelletta sp. of deep coral sea. Helv. Chim. Acta 74, 487-494 (1991)
13 Oku, N., Matsunaga, S., Wada, S. I., Watabe, S., and Fusetani, N., New isomalabricane triterpenes from the marine sponge Stelletta globostellata that induce morphological changes in rat fibroblasts. J. Nat. Prod. 63, 205-209 (2000)   DOI   ScienceOn
14 Costantino, V., Fattorusso, E., Imperatore, C., and Mangoni, A., Glycolipids from sponges. 11. Isocrasserides, novel glycolipids with five-membered cyclitol widely distributed in marine sponges. J. Nat. Prod. 65, 883-886 (2002)   DOI   ScienceOn
15 Su, J. Y., Meng, Y. H., Zeng, L. M., Fu, X., and Schmitz, F. J., Stellettin A, a new triterpenoid pigment from the marine sponge Stelletta tenuis. J. Nat. Prod. 57, 1450-1451 (1994)   DOI   ScienceOn
16 Hirota, H., Matsunaga, S., and Fusetani N., Bioactive marine metabolites. 32. Stellettamide A, an antifungal alkaloid from a marine sponge of the genus Stelletta. Tetrahedron Lett. 31, 4163-4164 (1990)   DOI   ScienceOn
17 Yan, S. J., Su, J. Y., Zhang, G. W., Wang, Y. H., and Li, H., Ketosterols from Stelletta tenuis. Zhongshan Daxue Xuebao 40, 54-57 (2001)
18 Matsunaga, S., Yamashita, T., Tsukamoto, S., and Fusetani, N., Three new antibacterial alkaloids from a marine sponge Stelletta species. J. Nat. Prod. 62, 1202-1204 (1999)   DOI   ScienceOn
19 Zhao, Q., Lee, S.-Y., Hong, J., Lee, C.-O., Im, K. S., Sim, C. J., Lee, D. S., and Jung, J. H., New acetylenic acids from the marine sponge Stelletta species. J. Nat. Prod. (2003a), in press
20 Ishibashi, M., Zeng, C. M., and Kobayashi, J., Keruffaride: structure revision and isolation from plural genera of Okinawan marine sponges. J. Nat. Prod. 56, 1856-1860 (1993)   DOI
21 Nozawa, D., Takikawa, H., and Mori, K., Synthesis and absolute configuration of stellettadine A: a marine alkaloid that induces larval metamorphosis in ascidians. Bioorg. Med. Chem. Lett. 11, 1481-1483 (2001)   DOI   ScienceOn
22 Tsukamoto, S., Yamashita, T., Matsunage, S., and Fusetani, N., Bioactive marine metabolites. 89. Stellettazole A: an antibacterial guanidinoimidazole alkaloid from a marine sponge Stelletta sp. Tetrahedron Lett. 40, 737-738 (1999b)   DOI   ScienceOn
23 Bergquist, P., Lawson, M. P., Lavis, A., and Cambie, R. C., Fatty acid composition and the classification of the Porifera. Biochem. Syst. Ecol. 12, 63-84 (1984)   DOI   ScienceOn
24 Fusetani, N., Asai, N., Matsunaga, S., Honda, K., and Yasumuro, K., Bioactive marine metabolites. 59. Cyclostellettamines A-F, pyridine alkaloids which inhibit binding of methylquinuclidinyl benzilate (QNB) to muscarinic acetylcholine receptors, from the marine sponge, Stelletta maxima. Tetrahedron Lett. 35, 3967-3970 (1994)   DOI   ScienceOn
25 Kim, D-K., Lim, Y. J, Kim, J. S., Park, J. H., Kim, N. D., Im, K. S., Hong, J., and Jung, J. H., A cyclitol derivative as a replication inhibitor from the marine sponge Petrosia sp. J. Nat. Prod. 62, 773-776 (1999)   DOI   ScienceOn
26 Costantino, V., Fattorusso, E., and Mangoni, A., Isolation of five membered cyclitol glycolipids, crasserides: unique glycerides from the sponge Pseudoceratina crassa. J. Org. Chem. 58, 186-191(1993)   DOI