Paralytic shellfish toxins (PSTs) and tetrodotoxin (TTX) of Korean pufferfish |
Lee, Ka Jeong
(Food Safety and Processing Research Division, National Institute of Fisheries Science)
Ha, Kwang Soo (Southeast Sea Fisheries Research Institute, National Institute of Fisheries Science) Jung, Yeoun Joong (Food Safety and Processing Research Division, National Institute of Fisheries Science) Mok, Jong Soo (South Sea Fisheries Research Institute, National Institute of Fisheries Science) Son, Kwang Tae (Food Safety and Processing Research Division, National Institute of Fisheries Science) Lee, Hee Chung (Food Safety and Processing Research Division, National Institute of Fisheries Science) Kim, Ji Hoe (Research and Development Planning Division, National Institute of Fisheries Science) |
1 | AOAC [Association of Official Analytical Chemists] International. Official methods of analysis of AOAC International. 18th ed. Gaithersburg, MD: AOAC International; 2005. |
2 | Kodama M, Ogata T, Noguchi T, Maruyama J, Hashimoto K. Occurrence of saxitoxin and other toxins in the liver of the pufferfish Takifugu pardalis. Toxicon. 1983;21:897-900. DOI |
3 | Lago J, Rodriguez LP, Blanco L, Vieites JM, Cabado AG. Tetrodotoxin, an extremely potent marine neurotoxin: distribution, toxicity, origin and therapeutical uses. Mar Drugs. 2015;13:6384-406. DOI |
4 | Ahmed FE. Seafood safety. Washington, DC: National Academy Press; 1991. |
5 | Alpert AJ. Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds. J Chromatogr A. 1990;499:177-96. DOI |
6 | Bricelj VM, Shumway SE. Paralytic shellfish toxins in bivalve molluscs: occurrence, transfer kinetics, and biotransformation. Rev Fish Sci. 1998;6:315-83. DOI |
7 | Itoi S, Yoshikawa S, Tatsuno R, Suzuki M, Asahina K, Yamamoto S, et al. Difference in the localization of tetrodotoxin between the female and male pufferfish Takifugu niphobles, during spawning. Toxicon. 2012;60:1000-4. DOI |
8 | Abbott JP, Flewelling LJ, Landsberg JH. Saxitoxin monitoring in three species of Florida puffer fish. Harmful Algae. 2009;8:343-8. DOI |
9 | Kao CY. Structure-activity relations of tetrodotoxin, saxitoxin, and analogues. Ann N Y Acad Sci. 1986;479:52-67. DOI |
10 | Jen HC, Lin SJ, Tsai YH, Chen CH, Lin ZC, Hwang DF. Tetrodotoxin poisoning evidenced by solid-phase extraction combining with liquid chromatography-tandem mass spectrometry. J Chromatogr B. 2008;871:95-100. DOI |
11 | Kim JH, Gong QL, Mok JS, Min JG, Lee TS, Park JH. Characteristics of puffer fish poisoning outbreaks in Korea (1991- 2002). J Food Hyg Saf. 2003;18:133-8. |
12 | Mortensen AM. Massive fish mortalities in the Faroe islands caused by a Gonyaulax excavate red tide. In: Anderson DM, White A, Baden DG, editors. Toxic dinoflagellates. New York, NY: Elsevier, 1985. p. 165-70. |
13 | Kim JH, Mok JS, Son KT, Kim JG, Jo MR, Kim PH, et al. Toxicity of the puffer fish, Takifugu xanthopterus (Kkachibok) and Takifugu stictonotus (Kkachilbok) from coastal area of Korea. Korean J Fish Aquac Sci. 2007;40:276-81. |
14 | Kim JH, Son KT, Mok JS, Oh EG, Kim JK, Lee TS. Toxicity of the puffer fish Takifugu porphyreus and Takifugu rubripes from coastal areas of Korea. Korean J Fish Aquac Sci. 2006;39:447-53. |
15 | Luckas B, Hummert C, Oshima Y. Analytical methods for paralytic shellfish poisons. In: Hallegraeff GM, Anderson DM, Cembella AD, editors. Manual on harmful marine microalgae. Paris, France: UNESCO; 2003. |
16 | Nakashima K, Arakawa O, Taniyama S, Nonaka M, Takatani T, Yamamori K, et al. Occurrence of saxitoxins as a major toxin in the ovary of a marine puffer Arothron firmamentum. Toxicon. 2004;43:207-12. DOI |
17 | Sato S, Ogata T, Borja V, Gonzales C, Fukuyo Y, Kodama M. Frequent occurrence of paralytic shellfish poisoning toxins as dominant toxins in marine puffer from tropical water. Toxicon. 2000;38:1101-9. DOI |
18 | Sato S, Ogata T, Kodama M. Trace amounts of saxitoxins in the viscera of chum salmon Oncorhynchus keta. Mar Ecol Prog Ser. 1998;175:295-8. DOI |
19 | Sephton DH, Haya K, Martin JL, LeGresley MM, Page FH. Paralytic shellfish toxins in zooplankton, mussels, lobsters and caged Atlantic salmon, Salmo salar, during a bloom of Alexandrium fundyense off Grand Manan island, in the Bay of Fundy. Harmful Algae. 2007;6:745-58. DOI |
20 | Song KC, Lee KJ, Yu HS, Mok JS, Kim JH, Lim KS, et al. Paralytic shellfish poisoning (PSP) analysis using liquid chromatography-tandem mass spectrometry. Korean J Fish Aquat Sci. 2013;46:154-9. DOI |
21 | Zaman L, Arakawa O, Shimosu A, Onoue Y. Occurrence of paralytic shellfish poison in Bangladeshi freshwater puffers. Toxicon. 1997;35:423-31. DOI |
22 | Kawabata T. Puffer Toxin. In: Ministry of Health and Welfare, editors. The manuals for the methods of food sanitation tests II. Tokyo: Japan Food Hygienic Association; 1978. p.232-40. |
23 | Kim JH, Son KT, Mok JS, Kim JK, Jo MR, Shim KB, et al. Toxicity of puffer fish, Arothron firmamentum (Byeolbok) and Lagocephalus spp. in Korea. Korean J Fish Aquac Sci. 2008;41:309-14. |
24 | Kodama M, Sato S, Sakamoto S, Ogata T. Occurrence of tetrodotoxin in Alexandrium tamarense, a causative dinoflagellate of paralytic shellfish poisoning. Toxicon. 1996;34:1101-5. DOI |
25 | Negri A, Llewellyn L. Comparative analyses by HPLC and the sodium channel and saxiphilin 3H-saxitoxin receptor assays for paralytic shellfish toxins in crustaceans and molluscs from tropical North West Australia. Toxicon. 1998;36:283-98. DOI |
26 | Schantz EJ. Chemistry and biology of saxitoxin and related toxins. Ann N Y Acad Sci. 1986;479:15-23. DOI |
27 | White AW. Sensitivity of marine fishes to toxins from the redtide dinoflagellate Gonyaulax excavate and implications for fish kills. Mar Biol. 1981;65:255-60. DOI |
28 | Jang J, Yotsu-Yamashita M. Distribution of tetrodotoxin, saxitoxin, and their analogs among tissues of the puffer fish Fugu pardalis. Toxicon. 2006;48:980-7. DOI |
29 | Ministry of Food and Drug Safety [MFDS]. Food Code. Chapter 2. Common standards and specifications for general foods; Cheongju, Korea: MFDS; 2021. |
30 | Dell'Aversano C, Hess P, Quilliam MA. Hydrophilic interaction liquid chromatography-mass spectrometry for the analysis of paralytic shellfish poisoning (PSP) toxins. J Chromatogr A. 2005;1081:190-201. DOI |
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