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http://dx.doi.org/10.5657/fas.2008.11.1.001

Antibacterial Activity of the Phaeophyta Ecklonia stolonifera on Methicillin-resistant Staphylococcus aureus  

Eom, Sung-Hwan (Department of Food Science and Technology, Pukyong National University)
Kang, Min-Seung (Department of Food Science and Technology, Pukyong National University)
Kim, Young-Mog (Department of Food Science and Technology, Pukyong National University)
Publication Information
Fisheries and Aquatic Sciences / v.11, no.1, 2008 , pp. 1-6 More about this Journal
Abstract
In an effort to discover an alternative therapeutic agent against methicillin-resistant Staphylococcus aureus (MRSA), several medicinal plants and seaweeds were evaluated for its antibacterial activity against MRSA. A methanolic extract of the Phaeophyta Ecklonia stolonifera exhibited significant antibacterial activity against MRSA. To perform more detailed investigation on antibacterial activity, the methanol extract of E. stolonifera was further fractionated with organic solvents such as hexane, dimethylchloride, ethyl acetate, and n-butanol. Among them, the hexane fraction showed the strongest antibacterial activity against MRSA strains with MIC from 500 to $600 {\mu}g/mL$. The fraction also exhibited a bactericidal activity against MRSA, indicating that E. stolonifera contains a bactericidal substance against MRSA.
Keywords
Antibiotic resistance; Anti-MRSA activity; Methicillin resistant Staphylococcus aureus; MRSA;
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