[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5657/fas.2005.8.1.006

New Cyclic Peroxides from a Sponge, Plakortis sp.

Lim Chi Won (Marine Bio21 Center, National Fisheries R&D Institute)
Cha Yong Jun (Department of Food Science and Nutrition, Changwon National University)
Kim Jin Soo (Division of Marine Bioscience Institute of Marine Industry, Gyeongsang National University)

Publication Information

Fisheries and Aquatic Sciences / v.8, no.1, 2005 , pp. 6-9 More about this Journal

Abstract

Two new cyclic peroxides were isolated from an undescribed sponge of the genus Plakortis sp. collected at Discovery Bay, Jamaica. The molecular structures were elucidated by interpreting ID and 2D NMR and HRMS data. The cyclic peroxides, Compound 1 and 2, exhibited significant antimicrobial activity against pathogenic bacteria and fungi with IC $_$ {50} values of 0.9-5.0 $$\mu$ g/mL and 0.7-8.0 $$\mu$ g/mL, respectively.

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Reference

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