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http://dx.doi.org/10.5657/fas.2002.5.2.097

Fungicidal Activity of Substance Purified from Marine Fungus Metabolites against Pyricularia oryzae  

Byun Hee-Guk (Department of Chemistry, Pukyong National University)
Kim Se-Kwon (Department of Chemistry, Pukyong National University)
Publication Information
Fisheries and Aquatic Sciences / v.5, no.2, 2002 , pp. 97-102 More about this Journal
Abstract
Pyricularia oryzae (P. oryzae), the cause of rice blast, is one of the most important fungal pathogens of rice. Seventy strains of marine fungi were isolated from marine algae, and it was measured antifungal activity against P. oryzae. Metabolites of marine fungus A-248 which isolated from marine algae showed strong antifungal activity against P. oryzae. The antifungal substance from the metabolites of marine fungus A-248 was extracted with ethylacetate, and then purified by preparative TLC and reverse-phase HPLC. The minimum inhibitory concentration (MIC) value was $0.18\mu g/mL$ for the antifungal activity of the substance purified from A-248 metabolites. The purified substance was similar to antifungal activity of rhizoxin, which is a commercial antifungal agent.
Keywords
Marine algae; Marine fungus; Pyricularia oryzae; Antifungal substances;
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