[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5657/fas.2002.5.1.032

Apoptosis in CHSE-214 Chinook Salmon Embryo Cells Infected with Hirame Rhabdovirus (HIRRV)

Sung Han-Gi (Department of Biology, Pusan National University)
Kim Yeong-Jin (Department of Fish Pathology, Yosu National University)
Jung Sung-Ju (Department of Fish Pathology, Yosu National University)
Choi Won-Chul (Department of Biology, Pusan National University)
Jung Tae-Sung (Lab of Fish & Shellfish Disease, College of Veterinary Gyeongsang National University)
Choi Tae-Jin (Department of Microbiology, Pukyong National University)
Oh Myung-Joo (Department of Fish Pathology, Yosu National University)

Publication Information

Fisheries and Aquatic Sciences / v.5, no.1, 2002 , pp. 32-35 More about this Journal

Abstract

In this study, we investigated the mechanism of cell death in rhabdovirus-infected cells, chinook salmon embryonic cell line (CHSE-2l4) infected with hirame rhabdovirus (HIRRV). Studies using light microscopy, fluorescence microscopy, TUNEL method, electron microscopy, and agarose gel electrophoresis revealed changes in the cell morphology and DNA fragmentation indicative of apoptosis in early infection. It was observed that HIRRV induced apoptosis as well as necrosis in infected cells.

Keywords

Apoptosis; Hirame rhabdovirus; HIRRV; CHSE-2l4 cell;

Citations & Related Records

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