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The Effect of Dietary Phytate Content on Iron Absorption and Status in Young Korean Women  

Kim, Ji-Hye (Department of Food and Nutrition, Seoul National University)
Li, Sun-Hee (Department of Food and Nutrition, Seoul National University)
Joung, Hyo-Jee (Department of Public Health, Graduate School of Public Health, Seoul National University)
Paik, Hee-Young (Department of Food and Nutrition, Seoul National University)
Publication Information
International Journal of Human Ecology / v.4, no.1, 2003 , pp. 35-44 More about this Journal
Abstract
This study investigated the effects of dietary phyate reduction on the apparent absorption and biochemical parameters of iron status in young Korean women. Fourteen healthy, young women consumed low and high phytate diets for ten days of each experimental period. Duplicate diet samples, a fasting blood sample on day 9, and complete fecal samples for five consecutive days starting from day 5 of each diet period were collected. The iron content of diet and fecal samples were analyzed to calculate apparent absorption. Serum samples were analyzed for iron, ferritin, transferrin receptor and TIBC; transferrin saturation was also calculated. The apparent absorption of iron tended to increase in the low phytate period (32.51%) compared to the high phytate period (17.91%), but the difference was not significant (p=0.06). Serum ferritin decreased and serum transferrin receptor increased significantly during the low phytate diet although the mean values were within the normal range. Serum iron and transferrin saturation did not change significantly. In conclusion, the results indicated that reducing dietary phytate for ten days negatively affected iron nutritional parameters, but it moderately and positively affected apparent iron absorption in young Korean women. Further research on the long-term effects of a low phytate diet with an adequate iron content for vows Korean women is necessary.
Keywords
dietary phytate; iron absorption; iron status;
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1 Bach, S. B., Hansen, M., Bukhave K, Jensen, M., Sorensen, S. S., Kristensen, L., Purslow, P., Skibsted, L. H., Sandstrom, B. (2003a). Nonheme-iron absorption from phytate-rich meal is increased by the addition of small amount of porkmeat. Am J Clin Nutr 77, 173-179
2 Cook, J. D., Skikne, B. S., Baynes, R D. (1994). Iron drficiency.: The global perspectives. Advan Exp Med Biol 358(1), 211-218
3 Hallberg, L., Rossander, L., Skanberg, A. B. (1987). Phytates and the inhibitory effect of branon iron absorption in man. Am J Clin Nutr 45, 988-996
4 Harland, B. F. and Oberleas, D. (1986). Anion-exchange method for determination of phytate in foods: Collaborative study. Journal of Association of Official Analytical Chemists 69(4), 667-670
5 Joung, H.J., Nam, G.Y., Yoon, S.,Lee, J., Shim, J. E. and Paik, H.Y., (2003) Bioavailable zinc intake of Korean adults in relation to phytate content of Korean foods. Manuscript submitted for publication
6 Korean Nutrition Society (2000). Food composition table. In Recommended dietary allowance(pp266-463). The Korean Nutrition Society
7 Lee, K., Kim, E., Kim, M.(1997). Iron nutritional status of female students in Kangnung National University. Kor J Community Nutr 2(1), 23-32
8 Gillooly, M., Bothwell, T. H., Charlton, R. W. (1984). Factors affecting the absorption of iron from cereals. Br J. Nutr 51,37-46   DOI   ScienceOn
9 Ministry of health and Welfare.(1999) 1998 National Health and Nutritional Examination survey report about health status of women. pp 115-116
10 Bach, S. B., Hansen, M., Bukhave, K, Jensen, M., Sorensen, S. S., Kristensen, L., Purslow, P., Skibsted, L. H., Sandstrom, B. (2003b). Increasing the cooking temperature of meat does not affect iron absorption from a phytate rich meal inwomen. J. Nutr 133, 94-97
11 Manary, M. J., Hots, C., Krebs, N. F, Gibson, R. S., Westcott, J. E., Broadhead, R L.(2002). Zinc homeostasis in Malawian children consuming a high phytate, Maze-based diet. Am J Clin Nutr 75, 1057-1061
12 Huddle, J.M., Gibson, R S., Cullian, T. R (1998). Is zinc a limiting nutrient in the diets of rural pregnant Malawian women? Br J Nutr 79, 257-265
13 Lee, J., Joung, H., Li, S., Paik, H. Y .(2003). Strategies to reduce phytate content in the Korean diet. Manuscript submitted for publication
14 Graf, E., Eaton, J. W. (1993). Suppression of colonic cancer by dietary phytic acid. Nutr Cancer 19, 11-19   DOI
15 Hurrell, R. E., Reddy, M. B., Juillerat, M., Cook, J. D. (2003). Degradation of phytic acid in cereal porridges improves iron absorption by human subjects. Am J Clin Nutr 77, 1213-9
16 Sauberlich, H. E. (1999). Assessment of nutritional status. pp 343-369. CRC Press
17 Hong, S. M., Kim, E. Z., Kim, S. R. (1999). A study on iron status and anemia of female college students of Ulsan city. J Korean Soc Food Sci Nutr 28(5), 1151-1157
18 West, C, E. (1996). Strategies to control nutritional anemia. Am J Clin Nutr 64, 789-790
19 Allen, L. H. (2001). Biological mechanism that might underlie iron's effects on fetal growth and preterm birth. J Nutr 131, 581s-589s
20 Hurrell, R E, Reddy, M. B., Burri, J., Cook, J. D. (2000). An evaluation of EDTA compounds for iron fortification of cereal-based foods. Br J Nutr 84, 903-10
21 Tumlaund. J. R, Durkin, N., Costa, E, Margen, S. (1986). Stable isotope studies of zinc absorption and retention in youngmen and elderly men. J. Nutr 116, 1239-1247
22 Morris, E. R, Ellis, R. (1989). Usefulness of the dietary phytic acid/zinc molar ratio as an index of zinc bioavailability to rats and humans. Biol Trace Elem Res 19, 107-117   DOI
23 Krebs, N. F. (2000). Overview of zinc absorption and excretion in the human gastrointestinal tract. J Nutr 130, 1374S-1377S
24 Kotsaki-Kovatsi, V. P., Kovatsi, L., Koehler-Samouilidou, G., Karavanis, M., Bacoyanni, E. (2001). Influence of inositolhexaphosphoric acid (phytic acid) on the copper distribution in tissues and the excretion of copper in rats. J Trace Elem Med Biol 14(4), 193-7   DOI   ScienceOn
25 Pallauf, J., Pippig, S., Most, E., Rimbach, G. (1999). Supplemental sodium phytate and microbial phytase influence iron availability in growing rats. J Trace Elements Med Biol 13, 134-140
26 Cosgrove, D. J. (1966). The chemistry and biochemistry of inositol phosphate. Rev Pure Appl Chem 16, 209-224
27 Hurrell, R E, Juillerat, M.A., Reddy, M.B., Lynch, S. R, Dassenko, S. A., Cook, J. D. (1992). Soy protein, phytate and iron absorption in man. Am J Clin Nutr 56, 573-578
28 Kye, S. H., Paik, H. Y. (1993). Iron nutriture and related dietary factors in apparently healthy young Korean women (2):Analysis of iron in major food items and assessment of intake and availability if dietary iron. Kor J Nutr 26(6), 703-714