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Indicator-free DNA Chip Array Using an Electrochemical System  

Park, Yong-Sung (School of Electrical, Electronic and Information Engineering, Wonkwang University)
Kwon, Young-Soo (Div. of Electrical, Electronic and Computer Eng., Dong-A University)
Park, Dae-Hee (School of Electrical, Electronic and Information Engineering, Wonkwang University)
Publication Information
KIEE International Transactions on Electrophysics and Applications / v.4C, no.4, 2004 , pp. 133-136 More about this Journal
Abstract
This research aims to develop a DNA chip array without an indicator. We fabricated a microelectrode array through photolithography technology. Several DNA probes were immobilized on an electrode. Then, target DNA was hybridized and measured electrochemically. Cyclic-voltammograms (CVs) showed a difference between the DNA probe and mismatched DNA in an anodic peak. This indicator-free DNA chip resulted in a sequence-specific detection of the target DNA.
Keywords
DNA probe; Hybridization; Indicator-free DNA chip; Immobilization; Target DNA;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
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