Effects of Graded Levels of Isomaltooligosaccharides on the Performance, Immune Function and Intestinal Status of Weaned Pigs |
Wang, X.X.
(State Key Laboratory of Animal Nutrition, China Agricultural University)
Song, P.X. (State Key Laboratory of Animal Nutrition, China Agricultural University) Wu, H. (State Key Laboratory of Animal Nutrition, China Agricultural University) Xue, J.X. (State Key Laboratory of Animal Nutrition, China Agricultural University) Zhong, X. (State Key Laboratory of Animal Nutrition, China Agricultural University) Zhang, L.Y. (State Key Laboratory of Animal Nutrition, China Agricultural University) |
1 | Wang, H. F., P. S. Lim, M. D. Kao, E. C. Chan, L. C. Lin, and N. P. Wang. 2001. Use of isomalto-oligosaccharide in the treatment of lipid profiles and constipation in hemodialysis patients. J. Ren. Nutr. 11:73-79. DOI |
2 | Wang, S., H. Zhu, C. Lu, Z. Kang, Y. Luo, L. Feng, and X. Lu. 2012. Fermented milk supplemented with probiotics and prebiotics can effectively alter the intestinal microbiota and immunity of host animals. J. Dairy Sci. 95:4813-4822. DOI |
3 | Watanabe, T., M. Watanabe, and K. Seiji. 2002. Prophylactic or ameliorating agent for immunological dysfunction, prophylactic or ameliorating agent for microbism, tumor immunological enhancer and prophylactic or ameliorating agent for in vivo various dysfunctions and functional food comprising alpha-1,6-bonded chain glucose oligomer as active ingredient. Japanese Patent, JP 2002161039. |
4 | Yen, C. H., Y. H. Tseng, Y. W. Kuo, M. C. Lee, and H. L. Chen. 2011. Long-term supplementation of isomaltooligosaccharides improved colonic microflora profile, bowel function, and blood cholesterol levels in constipated elderly people: a placebo-controlled, diet-controlled trial. Nutrition 27:445-450. DOI |
5 | Zhang, W. F., D. F. Li, W. Q. Lu, and G. F. Yi. 2003. Effects of isomalto-oligosaccharides on broiler performance and intestinal microflora. Poult. Sci. 82:657-663. DOI |
6 | Zhang, Q., B. Tan, K. Mai, W. Zhang, H. Ma, Q. Ai, X. Wang, and Z. Liufu. 2011. Dietary administration of Bacillus (B. licheniformis and B. subtilis) and isomaltooligosaccharide influences the intestinal microflora, immunological parameters and resistance against Vibrio alginolyticus in shrimp, Penaeus japonicus (Decapoda: Penaeidae). Aquac. Res. 42:943-952. DOI |
7 | Zhao, X., L. Li, Q. Luo, M. Ye, G. Luo, and Z. Kuang. 2015. Effects of mulberry (Morus alba L.) leaf polysaccharides on growth performance, diarrhea, blood parameters, and gut microbiota of early-weanling pigs. Livest. Sci. 177:88-94. DOI |
8 | Brocker, C., D. Thompson, A. Matsumoto, D. W. Nebert, and V. Vasiliou. 2010. Evolutionary divergence and functions of the human interleukin (IL) gene family. Hum. Genomics 5:30-55. DOI |
9 | Al-Banna, N. A., D. Pavlovic, M. Grundling, J. Zhou, M. Kelly, S. Whynot, O. Hung, B. Johnston, T. B. Issekutz, H. Kern, V. Cerny, and Ch. Lehmann. 2013. Impact of antibiotics on the microcirculation in local and systemic inflammation. Clin. Hemorheol. Microcirc. 53:155-169. |
10 | AOAC. 2000. Official Methods of Analysis. 17th edn. Association of Official Analytical Chemists, Gaithersburg, MD, USA. |
11 | Chen, H. L., Y. H. Lu, J. J. Lin, and L. Y. Ko. 2001. Effects of isomalto-oligosaccharides on bowel functions and indicators of nutritional status in constipated elderly men. J. Am. Coll. Nutr. 20:44-49. DOI |
12 | Delzenne, N. M. 2003. Oligosaccharides: state of the art. Proc. Nutr. Soc. 62:177-182. DOI |
13 | Goffin, D., N. Delzenne, C. Blecker, E. Hanon, C. Deroanne, and M. Paquot. 2001. Will isomalto-oligosaccharides, a wellestablished functional food in Asia, break through the European and American market? The status of knowledge on these prebiotics. Crit. Rev. Food Sci. Nutr. 51:394-409. |
14 | Hayashi, S., T. Hinotani, Y. Takasaki, and K. Imada. 1994. The enzymatic reaction for the production of panose and isomaltose by glucosyltransferase from Aureobasidium. Lett. Appl. Microbiol. 19:247-248. DOI |
15 | Kaneko, T., T. Matsukubo, T. Yatake, Y. Muramatsu, and Y. Takaesu. 1995a. Evaluation of acidogenicity of commercial isomaltooligosaccharides mixture and its hydrogenated derivative by measurement of pH response under human dental plaque. Biosci. Biotechnol. Biochem. 59:372-377. DOI |
16 | Kohmoto, T., K. Tsuji, T. Kaneko, M. Shiota, F. Fukui, H. Takaku, Y. Nakagawa, T. Ichikawa, and S. Kobayash. 1992. Metabolism of 13C-Isomaltooligosaccharides in healthy men. Biosci. Biotechnol. Biochem. 56:937-940. DOI |
17 | Kaneko, T., A. Yokoyama, and M. Suzuki. 1995b. Digestibility characteristics of isomaltooligosaccharides in comparison with several saccharides using the rat jejunum loop method. Biosci. Biotechnol. Biochem. 59:1190-1194. DOI |
18 | Ketabi, A., L. A. Dieleman, and M. G. Ganzle. 2011. Influence of isomalto-oligosaccharides on intestinal microbiota in rats. J. Appl. Microbiol. 110:1297-1306. DOI |
19 | Kik, M. J., J. Huisman, A. F. van der Poel, and J. M. Mouwen. 1990. Pathologic changes of the small intestinal mucosa of pigs after feeding Phaseolus vulgaris beans. Vet. Pathol. 27:329-334. DOI |
20 | Li, J., B. Tan, and K. Mai. 2009a. Dietary probiotic Bacillus OJ and isomaltooligosaccharides influence the intestine microbial populations, immune responses and resistance to white spot syndrome virus in shrimp (Litopenaeus vannamei). Aquaculture 291:35-40. DOI |
21 | Li, Y. J., G. Y. Zhao, W. Du, and T. J. Zhang. 2009b. Effect of dietary isomaltooligosaccharides on nutrient digestibility and concentration of glucose, insulin, cholesterol and triglycerides in serum of growing pigs. Anim. Feed Sci. Technol. 151:312- 315. DOI |
22 | Li, M., W. L. Liu, G. Y. Zhao, L. M. Yu, Y. H. Wu, Y. F. Wu, Z. Q. Pan, and Z. H. Shen. 2010. Effect of different oligosaccharides on immunity and production performance of piglets. Anim. Husb. Feed Sci. Z2:9-11. |
23 | Litman, G. W., J. P. Rast, M. J. Shamblott, R. N. Haire, M. Hulst, W. Roess, R. T. Litman, K. R. Hinds-Frey, A. Zilch, and C. T. Amemiya. 1993. Phylogenetic diversification of immunoglobulin genes and the antibody repertoire. Mol. Biol. Evol. 10:60-72. |
24 | Rehman, H., W. Vahjen, A. Kohl-Parisini, A. Ijaz, and J. Zentek. 2009. Influence of fermentable carbohydrates on the intestinal bacteria and enteropathogens in broilers. Worlds Poult. Sci. J. 65:75-90. DOI |
25 | Marquardt, R. R., L. Z. Jin, J. W. Kim, L. Fang, A. A. Frohlich, and S. K. Baidoo. 1999. Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia coli K88+ infection in neonatal and early-weaned piglets. FEMS Immunol. Med. Microbiol. 23:283-288. DOI |
26 | Mizubuchi, H., T. Yajima, N. Aoi, T. Tomita, and Y. Yoshikai. 2005. Isomalto-oligosaccharides polarize Th1-like responses in intestinal and systemic immunity in mice. J. Nutr. 135:2857- 2861. DOI |
27 | National Research Council. 1998. Nutrient Requirements of Swine. 10th Ed. National Academy Press, Washington, DC, USA. |
28 | Sung, H. Y., H. J. Jeong, and Y. S. Choi. 2004. Effects of fructans and isomaltooligosaccharide on large bowel mass and plasma and fecal immunoglobulin A in rat. Nutr. Sci. 7:196-200. |
29 | Thiex, N. J., H. Manson, S. Andersson, and J. A. Persson. 2002. Determination of crude protein in animal feed, forage, grain, and oilseeds by using block digestion with a copper catalyst and steam distillation into boric acid: collaborative study. J. AOAC Int. 85:309-317. |
30 | Thitaram, S. N., C. H. Chung, D. F. Day, A. Hinton Jr, J. S. Bailey, and G. R. Siragusa. 2005. Isomaltooligosaccharide increases cecal Bifidobacterium population in young broiler chickens. Poult. Sci. 84:998-1003. DOI |
31 | Vetere, A., A. Gamini, C. Campa, and S. Paoletti. 2000. Regiospecific transglycolytic synthesis and structural characterization of 6-O-alpha-glucopyranosyl-glucopyranose (isomaltose). Biochem. Biophys. Res. Commun. 274:99-104. DOI |
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