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http://dx.doi.org/10.5713/ajas.2012.12524

Historical Overview of the Effect of β-Adrenergic Agonists on Beef Cattle Production  

Johnson, Bradley J. (Department of Animal and Food Sciences, Texas Tech University)
Smith, Stephen B. (Department of Animal Science, Texas A&M University)
Chung, Ki Yong (Hanwoo Experiment Station, National Institute of Animal Science, RDA)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.27, no.5, 2014 , pp. 757-766 More about this Journal
Abstract
Postnatal muscle hypertrophy of beef cattle is the result of enhanced myofibrillar protein synthesis and reduced protein turnover. Skeletal muscle hypertrophy has been studied in cattle fed ${\beta}$-adrenergic agonists (${\beta}$-AA), which are receptor-mediated enhancers of protein synthesis and inhibitors of protein degradation. Feeding ${\beta}$-AA to beef cattle increases longissimus muscle cross-sectional area 6% to 40% compared to non-treated cattle. The ${\beta}$-AA have been reported to improve live animal performance, including average daily gain, feed efficiency, hot carcass weight, and dressing percentage. Treatment with ${\beta}$-AA increased mRNA concentration of the ${\beta}_2$ or ${\beta}_1$-adrenergic receptor and myosin heavy chain IIX in bovine skeletal muscle tissue. This review will examine the effects of skeletal muscle and adipose development with ${\beta}$-AA, and will interpret how the use of ${\beta}$-AA affects performance, body composition, and growth in beef cattle.
Keywords
${\beta}$-Adrenergic Agonists; Skeletal Muscle; Beef Cattle;
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