1 |
Yaswen, L., N. Diehl, M. Brennan and U. Hochgeschwender. 1999. Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. Nat. Med. 5: 1066-1070.
DOI
ScienceOn
|
2 |
Stapleton, D., E. Woollatt, K. I. Mitchelhill, J. K. Nicholl, C. S. Fernandez, B. J. Michell, L. A. Witters, D. A. Power, G. R. Sutherland and B. E. Kemp. 1997. AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location. FEBS Lett. 409:452-456.
DOI
ScienceOn
|
3 |
Takahashi, K. A. and R. D. Cone. 2005. Fasting induces a large, leptin-dependent increase in the intrinsic action potential frequency of orexigenic arcuate nucleus neuropeptide Y/Agouti-related protein neurons. Endocrinology 146:1043-1047.
DOI
ScienceOn
|
4 |
Toshinai, K., Y. Date, N. Murakami, M. Shimada, M. S. Mondal, T. Shimbara, J. L. Guan, Q. P. Wang, H. Funahashi, T. Sakurai, S. Shioda, S. Matsukura, K. Kangawa and M. Nakazato. 2003. Ghrelin-induced food intake is mediated via the orexin pathway. Endocrinology 144:1506-1512.
DOI
ScienceOn
|
5 |
Tsujii, S., and G. A. Bray. 1989. Acetylation alters the feeding response to MSH and beta-endorphin. Brain Res. Bull. 23: 165-169.
DOI
ScienceOn
|
6 |
Turnley, A. M., D. Stapleton, R. J. Mann, L. A. Witters, B. E. Kemp and P. F. Bartlett. 1999. Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J. Neurochem. 72: 1707-1716.
|
7 |
Xue, B. and B. Kahn. 2006. AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. J. Physiol. 574:73-83.
DOI
ScienceOn
|
8 |
Xu, P., C. J. Denbow, N. Meiri and D. M. Denbow. 2011. Fasting of 3-day-old chickens leads to changes in histone H3 methylation status. Physiol. Behav. 105:276-282.
|
9 |
Xu, P., P. B. Siegel and D. M. Denbow. 2011. Genetic selection for body weight in chickens has altered responses of the brain's AMPK system to food intake regulation effect of ghrelin, but not obestatin. Behav. Brain Res. 221:216-226.
DOI
ScienceOn
|
10 |
Proszkowiec-Weglarz, M. and M. P. Richards. 2009. Expression and activity of the 5'-adenosine monophosphate-activated protein kinase pathway in selected tissues during chicken embryonic development. Poult. Sci. 88:159-178.
DOI
ScienceOn
|
11 |
Richards, M. P., R. W. Rosebrough, C. N. Coon and J. P. Mcmurtry. 2010. Feed intake regulation for the female broiler breeder: In theory and in practice. J. Appl. Poult. Res. 19:182-193.
DOI
|
12 |
Richards, M. P. and M. Proszkowiec-Weglarz. 2007. Mechanisms regulating feed intake, energy expenditure, and body weight in poultry. Poult. Sci. 86:1478-1490.
DOI
|
13 |
Roseberry, A. G., H. Liu, A. C. Jackson, X. Cai and J. M. Friedman. 2004. Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice. Neuron 41:711-722.
DOI
ScienceOn
|
14 |
Saito, E., H. Kaiya, T. Tachibana, S. Tomonaga, D. Denbow, K. Kangawa and M. Furuse. 2005. Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chickens. Regul. Pept. 125:201-208.
DOI
ScienceOn
|
15 |
Scott, J. W., S. A. Hawley, K. A. Green, M. Anis, G. Stewart, G. A. Scullion, D. G. Norman and D. G. Hardie. 2004. CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations. J. Clin. Invest. 113: 274-284.
DOI
ScienceOn
|
16 |
Shaw, R. J., K. A. Lamia, D. Vasquez, S. H. Koo, N. Bardeesy, R. A. DePinho, M. Montminy and L. C. Cantley. 2005. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310:1642-1646.
DOI
ScienceOn
|
17 |
Stapleton, D., K. I. Mitchelhill, G. Gao, J. Widmer, B. J. Michell, T. The, C. M. House, C. S. Fernandez, T. Cox, L. A. Witters and B. E. Kemp. 1996. Mammalian AMP-activated protein kinase subfamily. J. Biol. Chem. 271:611-614.
DOI
|
18 |
Boudeau, J., A. F. Bass, M. Deak, N. A. Morrice, A. Kieloch, M. Schutkowski, A. R. Prescott, H. C. Clevers and D. R. Alessi. 2003. MO25 interact with STRAD enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J. 22:5102-5114.
DOI
ScienceOn
|
19 |
Bass, A. F., J. Boudeau, G. P. Sapkota, L. Smit, R. Medema, N. A. Morrice, D. R. Alessi and H. C. Clevers. 2003. Activation of the tumor suppressor kinase LKB1 by the STE20-like pseudokinase STRAD. EMBO J. 22:3062-3072.
DOI
ScienceOn
|
20 |
Bennett, M., Y. Seo, S. Datta, D. Shin and T. Osborne. 2008. Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver. J. Biol. Chem. 283:15628-15637.
DOI
ScienceOn
|
21 |
Carling, D., M. Sanders and A. Woods. 2008. The regulation of AMP-activated protein kinase by upstream kinases. Int. J. Obes. (Lond). 32:S55-S59.
|
22 |
Cheung, P., I. Salt, S. Davies, D. Hardie and D. Carling.2000. Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding. Biochem. J. 346:659-669.
DOI
|
23 |
Olfert, E. D., B. M. Cross and A. A. McWilliam. 1993. Guide to the care and use of experimental animals. Canadian Council on Animal Care, 1000-151 Slater Street, Ottawa, Ontario K1P 5H3.
|
24 |
Morton, G. J., D. E. Cummings, D. G. Baskin, G. S. Barsh and M. W. Schwartz. 2006. Central nervous system control of food intake and body weight. Nature 443:289-295.
DOI
ScienceOn
|
25 |
Mu, J., J. T. Brozinick, O. Valladares, M. Bucan and M. J. Birnbaum. 2001. A role for AMP-activated protein kinase in contraction-and hypoxia-regulated glucose transport in skeletal muscle. Mol. Cell 7:1085-1094.
DOI
ScienceOn
|
26 |
Musi, N., N. Fujii, M. F. Hirshman, I. Ekberg, S. Fröberg, O. Ljungqvist, A. Thorell and L. J. Goodyear. 2001. AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise. Diabetes 50: 921-927.
DOI
ScienceOn
|
27 |
Nakazato, M., N. Murakami, Y. Date, M. Kojima, H. Matsuo, K. Kangawa and S. Matsukura. 2001. A role for ghrelin in the central regulation of feeding. Nature 409:194-198.
DOI
ScienceOn
|
28 |
Obici, S., Z. Feng, A. Arduini, R. Conti and L. Rossetti. 2003. Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production. Nat. Med. 9: 756-761.
DOI
ScienceOn
|
29 |
Ollmann, M. M., B. D. Wilson, Y. K. Yang, J. A. Kerns, Y. Chen, I. Gantz and G. S. Barsh.1997. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278:135-138.
DOI
ScienceOn
|
30 |
Proszkowiec-Weglarz, M., M. P. Richards, B. D. Humphrey, R. W. Rosebrough and J. P. McMurtry. 2009. AMP-activated protein kinase and carbohydrate response element binding protein: a study of two potential regulatory factors in the hepatic lipogenic program of broiler chickens. Comp. Biochem. Physiol. B. Biochem. Mol. Biol. 154:68-79.
DOI
ScienceOn
|
31 |
Proszkowiec-Weglarz, M., M. P. Richards, R. Ramachandran and J. McMurtry. 2006. Characterization of the AMP-activated protein kinase pathway in chickens. Comp. Biochem. Physiol. B. Biochem. Mol. Biol. 143:92-106.
DOI
ScienceOn
|
32 |
Lopez, M., R. Lage, A. K. Saha, D. Perez-Tilve, M. J. Vazquez, L. Varela, S. Sangiao-Alvarellos, S. Tovar, K. Raghay, S. Rodríguez-Cuenca, R. M. Deoliveira, T. Castaneda, R. Datta, J. Z. Dong, M. Culler, M. W. Sleeman, C. V. Alvarez, R. Gallego, C. J. Lelliott, D. Carling, M. H. Tschop, C. Diéguez and A. Vidal-Puig. 2008. Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. Cell Metab. 7:389-399.
DOI
ScienceOn
|
33 |
Lage, R., C. Dieguez, A. Vidal-Puig and M. Lopez. 2008. AMPK: a metabolic gauge regulating whole-body energy homeostasis. Trends Mol. Med. 14:539-549.
DOI
ScienceOn
|
34 |
Minokoshi, Y., T. Alquier, N. Furukawa, Y. B. Kim, A. Lee, B. Xue, J. Mu, F. Foufelle, P. Ferre, M. J. Birnbaum, B. J. Stuck and B. B. Kahn. 2004. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 428:569-574.
DOI
|
35 |
Lim, C. T., B. Kola and M. Korbonits. 2010. AMPK as a mediator of hormonal signalling. J. Mol. Endocrinol. 44:87-97.
DOI
ScienceOn
|
36 |
Livak, K. J. and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-[Delta][Delta]CT method. Methods 25:402-408.
DOI
ScienceOn
|
37 |
Marsin, A. S., L. Bertrand, M. H. Rider, J. Deprez, C. Beauloye, M. F. Vincent, G. Van den Berghe, D. Carling and L. Hue. 2000. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia. Curr. Biol. 10:1247-1255.
DOI
ScienceOn
|
38 |
Mitchelhill, K. I., D. Stapleton, G. Gao, C. House, B. Michell, F. Katsis, L. A. Witters and B. E. Kemp. 1994. Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase. J. Biol. Chem. 269:2361-2364.
|
39 |
Momcilovic, M., S. P. Hong and M. Carlson. 2006. Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro. J. Biol. Chem. 281:25336-25343.
DOI
ScienceOn
|
40 |
He, W., T. Lam, S. Obici and L. Rossetti. 2006. Molecular disruption of hypothalamic nutrient sensing induces obesity. Nat. Neurosci. 9:227-233.
DOI
ScienceOn
|
41 |
Hong, S. P., F. C. Leiper, A. Woods, D. Carling and M. Carlson. 2003. Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc. Natl. Acad. Sci. USA. 100:8839-8843.
DOI
ScienceOn
|
42 |
Kola, B. 2008. Role of AMP-activated protein kinase in the control of appetite. J. Neuroendocrinol. 20:942-951.
DOI
ScienceOn
|
43 |
Hurley, R., K. A. Anderson, J. M. Franzone, B. E. Kemp, A. R. Means and L. A. Witters. 2005. The /calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases. J. Biol. Chem. 280:29060-29066.
DOI
ScienceOn
|
44 |
Jenne, D. E., H. Reimann, J. Nezu, W. Friedel, S. Loff, R. Jeschke, O. Müller, W. Back and M. Zimmer. 1998. Puetz-Jeghers syndrome is caused by mutation in a novel serine threonine kinase. Nat. Genet. 18:38-43.
DOI
ScienceOn
|
45 |
Khan, M., K. Dodo, K. Yahata, S. Nishimoto, H. Ueda, T. Taneike, T. Kitazawa and Y. Hosaka. 2006. Intracerebroventricular administration of growth hormone releasing peptide-6 (GHRP-6) inhibits food intake, but not food retention of crop and stomach in neonatal chicks. J. Poult. Sci. 43:35-40.
DOI
|
46 |
Kola, B., M. Boscaro, G. A. Rutter, A. B. Grossman and M.Korbonits. 2006. Expanding role of AMPK in endocrinology. Trends Endocrinol. Metab. 17:205-215.
DOI
ScienceOn
|
47 |
Lam, T. K., G. J. Schwartz and L. Rossetti. 2005. Hypothalamic sensing of fatty acids. Nat. Neurosci. 8:579-584.
DOI
ScienceOn
|
48 |
Lane, M. D., Z. Hu, S. H. Cha, Y. Dai, M. Wolfgang and A. Sidhaye. 2005. Role of malonyl-CoA in the hypothalamic control of food intake and energy expenditure. Biochem. Soc. Trans. 33:1063-1067.
DOI
ScienceOn
|
49 |
Dzamko, N., B. J. van Denderen, A. L. Hevener, S. B. Jørgensen, J. Honeyman, S. Galic, Z. P. Chen, M. J. Watt, D. J. Campbell, G. R. Steinberg and B. E. Kemp. 2010. AMPK beta1 deletion reduces appetite, preventing obesity and hepatic insulin resistance. J. Biol. Chem. 285:115-122.
DOI
ScienceOn
|
50 |
Foretz, M., N. Ancellin, F. Andreelli, Y. Saintillan, P. Grondin, A. Kahn, B. Thorens, S. Vaulont and B. Viollet. 2005. Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver. Diabetes 54:1331-1339.
DOI
ScienceOn
|
51 |
Hahn, T., J. Breininger, D. Baskin and M. Schwartz. 1998. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons. Nat. Neurosci. 1:271-272.
DOI
ScienceOn
|
52 |
Hardie, D. and S. Hawley. 2001. AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays 23:1112-1119.
DOI
ScienceOn
|
53 |
Hardie, D. G., J. W. Scott, D. A. Pan and E. R. Hudson. 2003. Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett. 546:113-120.
DOI
ScienceOn
|
54 |
Hawley, S. A., M. Davison, A. Woods, S. P. Davies, R. K. Beri, D. Carling and D. G. Hardie. 1996. Characterization of the AMP-activated protein kinase from rat liver and identification of threonine-172 as the major site at which it phosphorylates AMP-activated protein kinase. J. Biol. Chem. 271:27879-27887.
DOI
ScienceOn
|
55 |
Hawley, S. A., D. A. Pan, K. J. Mustard, L. Ross, J. Bain, A. M. Edelman, B. G. Frenguelli and D. G. Hardie. 2005. Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab. 2:9-19.
DOI
ScienceOn
|
56 |
Hemminki, A., D. Markie, I. Tomlinson, E. Avizienyte, S. Roth, A. Loukola, G. Bignell, W. Warren, M. Aminoff, P. Hoglund, H. Järvinen, P. Kristo, K. Pelin, M. Ridanpaa, R. Salovaara, T. Toro, W. Bodmer, S. Olschwang, A. S. Olsen, M. R. Stratton, A. de la Chapelle and L. A. Aaltonen. 1998. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 391: 184-187.
DOI
ScienceOn
|
57 |
Cowley, M., J. L. Smart, M. Rubinstein, M. G. Cerdán, S. Diano, T. L. Horvath, R. D. Cone and M. L. Low. 2001. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 411:480-484.
DOI
ScienceOn
|
58 |
Claret, M., M. A. Smith, R. L. Batterham, C. Selman, A. I. Choudhury, L. G. Fryer, M. Clements, H. Al-Qassab, H. Heffron, A. W. Xu, J. R. Speakman, G. S. Barsh, B. Viollet, S. Vaulont, M. L. Ashford, D. Carling and D. J. Withers. 2007. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J. Clin. Invest. 117:2325-2336.
DOI
ScienceOn
|
59 |
Close, B., K. Banister, V. Baumans, E. M. Bernoth, N. Bromage, J. Bunyan, W. Erhardt, P. Flecknell, N. Gregory, H. Hackbarth, D. Morton and C. Warwick. 1997. Recommendations for euthanasia of experimental animals: Part 2. DGXT of the European Commission. Lab. Anim. 31:1-32.
DOI
ScienceOn
|
60 |
Corton, J. M., J. G. Gillespie and D. G. Hardie. 1994. Role of the AMP-activated protein kinase in the cellular stress response. Curr. Biol. 4:315-324.
DOI
ScienceOn
|
61 |
da Silva Xavier, G., I. Leclerc, I. P. Salt, B. Doiron, D. G. Hardie, A. Kahn and G. A. Rutter. 2000. Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression. Proc. Natl. Acad. Sci. USA. 97:4023-4028.
DOI
ScienceOn
|
62 |
Date, Y., N. Murakami, K. Toshinai, S. Matsukura, A. Niijima, H. Matsuo, K. Kangawa and M. Nakazato. 2002. The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology 123:1120-1128.
DOI
ScienceOn
|
63 |
Dridi, S., C. Ververken, F. B. Hillgartner, A. Lutgarde, E. Van der Gucht, L. Cnops, E. Decuypere and J. Buyse. 2006. FAS inhibitor cerulenin reduces food intake and melanocortin receptor gene expression without modulating the other (an)orexigenic neuropeptides in chickens. Am. J. Physiol. Regul. Integr. Comp. Physiol. 291:R138-R147.
DOI
ScienceOn
|