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http://dx.doi.org/10.5713/ajas.2011.11164

Effect of Corticosterone on Hypothalamic Corticotropin-releasing Hormone Expression in Broiler Chicks (Gallus gallus domesticus) Fed a High Energy Diet  

Song, Zhigang (College of Animal Science and Technology, Shandong Agricultural University)
Yuan, Lei (College of Animal Science and Technology, Shandong Agricultural University)
Jiao, Hongchao (College of Animal Science and Technology, Shandong Agricultural University)
Lin, Hai (College of Animal Science and Technology, Shandong Agricultural University)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.24, no.12, 2011 , pp. 1736-1743 More about this Journal
Abstract
This paper reports the peripheral and central effect of corticosterone on feed intake and hypothalamic corticotropinreleasing hormone (CRH) gene expression in chicks fed a high energy diet. Three experiments were conducted: corticosterone was supplemented to the feed (30 mg/kg diet), injected subcutaneously (s.c., 4 mg/kg body weight) or intracerebroventricularly (i.c.v., 4 ng). The results showed that dietary corticosterone significantly increased feed intake. The s.c. corticosterone administration increased feed intake within 1 to 3 h and at 1 to 5 h after the injection. The i.c.v. corticosterone administration increased feed intake within 1 h after the injection, but not at 1 to 3 h. Dietary supplementation and s.c. injection of corticosterone decreased the CRH gene expression in the hypothalamus. Therefore, peripheral corticosterone exerted a decreased effect on hypothalamic CRH mRNA levels, and corticosterone had a stimulating effect on feed intake in broiler chicks fed a high energy diet.
Keywords
Broiler Chicks; Corticosterone; Corticotropin-releasing Hormone; Feed Intake;
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