Browse > Article
http://dx.doi.org/10.5713/ajas.2011.11007

Dietary Tea Catechin Inclusion Changes Plasma Biochemical Parameters, Hormone Concentrations and Glutathione Redox Status in Goats  

Zhong, Rongzhen (Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of Sciences)
Xiao, Wenjun (National Engineering Center of Botanical Functional Ingredients Utilization, Hunan Agricultural University)
Ren, Guopu (Department of Food Science and Engineering, Central South University of Forestry and Technology)
Zhou, Daowei (Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences)
Tan, Chuanyan (Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of Sciences)
Tan, Zhiliang (Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of Sciences)
Han, Xuefeng (Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of Sciences)
Tang, Shaoxun (Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of Sciences)
Zhou, Chuanshe (Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of Sciences)
Wang, Min (Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of Sciences)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.24, no.12, 2011 , pp. 1681-1689 More about this Journal
Abstract
The beneficial effects of tea catechins (TCs) are related not only to their antioxidant potential but also to the improvement of animal meat quality. In this study, we assessed the effects of dietary TC supplementation on plasma biochemical parameters, hormone responses, and glutathione redox status in goats. Forty Liuyang goats were randomly divided into four equal groups (10 animals/group) that were assigned to four experimental diets with TC supplementation at 4 levels (0, 2,000, 3,000 or 4,000 mg TC/kg DM feed). After a 60-day feeding trial, all goats were slaughtered and sampled. Dietary TC treatment had no significant effect on blood biochemical parameters, however, low-density lipoprotein cholesterol (p<0.001), triglyceride (p<0.01), plasma urea nitrogen (p<0.01), and glucose (p<0.001) decreased and total protein (p<0.01) and albumin (p<0.05) increased with the feeding time extension, and day 20 was the turning point for most of changes. Interactions were found in glutathione (p<0.001) and the ratio of reduced and oxidized glutathione (p<0.05) in whole blood between treatment and feeding time. Oxidized glutathione in blood was reduced (p<0.05) by 2,000 mg TC/kg feed supplementation, and a similar result was observed in longissimus dorsi muscle. Though plasma glutathione peroxidase (p<0.01) and glutathione reductase (p<0.05) activities were affected by treatment and feeding time interactions, and glutathione S-transferases activity increased with feeding day extension, no changed values appeared in longissimus dorsi muscle. In conclusion, dietary TC supplementation affected the concentrations of some blood metabolites and accelerated GSH depletion in the blood of goats. In terms of less high-density lipoprotein cholesterol, the highest insulin and IGF-I concentrations, the highest ratio of reduced and oxidized glutathione in plasma, the dosage of 2,000 mg TC/kg feed might be desirable for growing goats to prevent glutathione depletion and keep normal physiological metabolism.
Keywords
Plasma; Tea; Catechin; Biochemical and Hormone Parameters; Glutathione Redox; Goats;
Citations & Related Records

Times Cited By Web Of Science : 0  (Related Records In Web of Science)
Times Cited By SCOPUS : 0
연도 인용수 순위
  • Reference
1 Zelko, I. N., T. J. Mariani and R. J. Folz. 2002. Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution and expression. Free Radical Bio. Med. 33:337-349.   DOI   ScienceOn
2 Raederstoff, D. G., M. F. Schlachter, V. Elste and P. Weber. 2003. Effect of EGCG on lipid absorption and plasma lipid levels in rats. J. Nutr. Biochem. 14:326-332.   DOI   ScienceOn
3 Riesmersma, R. A., C. A. Rice-Evans, R. M. Tyrrell, M. N. Clifford and M. E. J. Lean. 2001. Tea flavonoids and cardiovascular health. Q. J. Med. 94:177-182.   DOI   ScienceOn
4 Rosenblat, M., N. Volkova, R. Coleman, Y. Almagor and M. Aviram. 2008. Antiatherogenicity of extra virgin olive oil and its enrichment with green tea polyphenols in the atherosclerotic apolipoprotein-E-deficient mice: enhanced macrophage cholesterol efflux. J. Nutr. Biochem. 19:514-523.   DOI   ScienceOn
5 Sabu, M. C., K. Smitha and R. Kuttan. 2002. Anti-diabetic activity of green tea polyphenols and their role in reducing oxidative stress in experimental diabetes. J. Ethnopharmacol. 83:1009-1016.
6 Samiec, P. S., C. Drews-Botsch, E. W. Flagg, J. C. Kurtz, P. Jr. Sternberg, R. L. Reed and D. P. Jones. 1998. Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes. Free Radic. Biol. Med. 24:699-704.   DOI   ScienceOn
7 Sgorlon, S., G. Stradaioli, B. Stefanon, G. Altimer and R. Della-Loggia. 2005. Dietary grape polyphenols modulate oxidative stress in ageing rabbits. In Proceedings of 16th Nat. Congr. Aspa, Torino, Italy. Ital. J. Anim. Sci. 4:541-543.
8 Shirai, N. and H. Suzuki. 2003. Effects of simultaneous docosahexaenoic acid and catechin intakes on the plasma and liver lipids in low- and high-fat diet fed mice. Nutr. Res. 23:959-969.   DOI   ScienceOn
9 Statistical Analysis System. 2002: User's guide: statistics. Version 9.1 Edition. SAS Inc., Cary, NC, USA.
10 Steinberg, D. and J. L. Witztum. 2002. Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis? Circulation 105:2107-2011.   DOI   ScienceOn
11 Meister, A. and M. E. Anderson. 1983. Glutathione. Annu. Rev. Biochem. 52:711-760.   DOI   ScienceOn
12 Minka, N. S., J. O. Ayo, A. K. B. Sackey and A. B. Adelaiye. 2009. Assessment and scoring of stresses imposed on goats during handling, loading, road transportation and unloading, and the effect of pretreatment with ascorbic acid. Livest. Sci. 125:275-282.   DOI   ScienceOn
13 Na, H. K. and Y. J. Surh. 2008. Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG. Food Chem. Toxicol. 46:1271-1278.   DOI   ScienceOn
14 Navarro, J., E. Obrador, J. A. Pellicer, M. Asensi, J. Vina and J. M. E. Strela. 1997. Blood glutathione as an index of radiation-induced oxidative stress in mice and humans. Free Radic. Biol. Med. 22:1203-1209.   DOI   ScienceOn
15 Nonaka, G., O. Kawakami and I. Nishioka. 1983. Tannins and related compounds. XV. A new class of dimeric flavan-3-ol gallates, theasineneins A and B, and proanthocyanidin gallates from green tea leaf. Chem. Pharm. Bull. 31:3906-3910.   DOI
16 Nordberg, J. and E. S. J. Arner. 2001. Reactive oxygen species, antioxidant and the mammalian thioredoxin system. Free Radic. Biol. Med. 31:1287-1312.   DOI   ScienceOn
17 NRC. 1981. Nurient requirements of goats: Angora, dairy and meat goats in temperate and tropical countries. Washington DC: National Academy Press.
18 Jones, D. P. 2006. Redefining oxidative stress. Antioxid. Redox Sign. 8:1865-1879.   DOI   ScienceOn
19 Pantke, U., T. Volk, M. Smutzler, W. J. Kox, N. Sitte and T. Grune. 1999. Oxidized proteins as a marker of oxidative stress during coronary heart surgery. Free Radic. Biol. Med. 27:1080-1086.   DOI   ScienceOn
20 Periasamy, S., E. S. Kuruvimalai and S. S. Chennam. 2007. Attenuation of 4-Nitroquinoline 1-oxide induced in vitro lipid oxidation by green tea polyphenols. Life Sci. 80:1080-1086.   DOI   ScienceOn
21 Kannan, G., K. E. Saker, T. H. Terrill, B. Kouakou, S. Galipalli and S. Gelaye. 2007. Effect of seaweed extract supplementation in goats exposed to simulated preslaughter stress. Small Rumin. Res. 73:221-227.   DOI   ScienceOn
22 Khan, S. A., P. Priyamvada, N. A. Arivarasu, S. Khan and A. N. K. Yusufi. 2007. Influence of green tea on enzymes of carbohydrate metabolism, antioxidant defense, and plasma membrane in rat tissues. Nutr. 23:687-695.   DOI   ScienceOn
23 Li, X., C. E. Cobb, K. E. Hill, R. F. Burk and J. M. May. 2001. Mitochondrial uptake and recycling of ascorbic acid. Arch. Biochem. Biophys. 87:143-153.
24 Littell, R. C., G. A. Milliken, W. W. Stroup and R. D. Wolfinger. 1996. SAS system for mixed models. SAS Inst. Inc., Cary, NC.
25 Liu, K., T. E. Cuddy and G. N. Pierce. 1992. Oxidative status of lipoproteins in coronary disease patients. Am. Heart J. 123:285-290.   DOI   ScienceOn
26 Liu, Z., L. P. Ma, B. Zhou and Z. L. Liu. 2000. Antioxidative effects of green tea polyphenols on free radical initiated and photosensitized oxidation of human low density lipoprotein. Chem. Phys. Lipids 106:53-63.   DOI   ScienceOn
27 Glatzle, D., J. P. Vuilleumier, F. Weber and K. Decker. 1974. Glutathione reductase test with whole blood, a convenient procedure for the assessment of the riboflavin status in human. Experientia 30:665-667.   DOI   ScienceOn
28 Lowry, O. H., N. J. Rosenbrough, A. L. Farr and R. J. Randall. 1951. Protein measurement with the folin phenol reagent. J. Biol. Chem. 134:265-275.
29 Malet, P. F. 1985. Animal models of gallstone formation. In Gallstones (Ed. S. Cohen and R. D. Soloway). New York: Edinburgh7 Churchill and Livingstone, 309-333.
30 Mason, L. M., S. A. Hogan, A. Lynch, P. G. O'Sullivan and J. P. Kerry. 2005. Effects of restricted feeding and antioxidant supplementation on pig performance and quality characteristics of longissimus dorsi muscle from Landrace and Duroc pigs. Meat Sci. 70:307-317.   DOI   ScienceOn
31 Granado-Serrano, A. B., M. A. Martín, L. Goya, L. Bravo and S. Ramos. 2009. Time-course regulation of survival pathways by epicatechin on HepG2 cells. J. Nutr. Biochem. 20:115-124.   DOI   ScienceOn
32 Habig, W. H., M. J. Pabseit and W. B. Jakoby. 1974. Glutathione transferase. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249:7130-7139.
33 Hara, Y. 2001. Lipid lowering effects. Green tea. New York: Marcel Dekker, 112-128.
34 Hashim, M. S., S. Lincy, V. Remya, M. Teena and L. Anila. 2005. Effect of polyphenolic compounds from Coriandrum sativum on $H_2O_2-induced$ oxidative stress in human lymphocytes. Food Chem. 92:653-660.   DOI   ScienceOn
35 He, Y. and F. Shahidi. 1997. Antioxidant activity of green tea and its catechins in a fish meat model system. J. Agric. Food Chem. 45:4262-4266.   DOI   ScienceOn
36 Ikeda, I., Y. Imasato, E. Sasaki, M. Nakayama, H. Nagao, T. Takeo, F. Yayabe and M. Sugano. 1992. Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. Biochim. Biophys. Acta. 1127:141-146.   DOI   ScienceOn
37 Henry, J. P. 1984. Stephens-Larson P: Reduction of chronic psychosocial hypertension in mice by decaffeinated tea. Hypertension 6:437-444.   DOI
38 Hsu, C. S., W. C. Chiu and S. L. Yeh. 2003. Effects of soy isoflavone supplementation on plasma glucose, lipids, and antioxidant enzyme activities in streptozotocin-induced diabetic rats. Nutr. Res. 23:67-75.   DOI   ScienceOn
39 Hultberg, M. and B. Hultberg. 2006. The effect of different antioxidants on glutathione turnover in human cell lines and their interaction with hydrogen peroxide. Chem. Biol. Interact. 163:192-198   DOI   ScienceOn
40 Chou, F. P., Y. C. Chu, J. D. Hsu, H. C. Chiang and C. J. Wang. 2000. Specific induction of glutathione S-transferase GSTM2 subunit expression by epigallocatechin gallate in rat liver. Biochem. Pharmacol. 60:643-650.   DOI   ScienceOn
41 Cnubben, N. H. P., I. M. C. M. Rietjens, H. Wortelboer, J. V. Zanden and P. J. V. Bladeren. 2001. The interplay of glutathione-related processes in antioxidant defense. Environ. Toxicol. Pharmacol. 10:141-152.   DOI   ScienceOn
42 Cooper, A. J. L. and B. S. Kristal. 1997. Multiple roles of glutathione in the central nervous system. Biol. Chem. 378:793-802.
43 Coruh, N., S. A. G. Celep, F. Ozgokce and M. İscan. 2007. Antioxidant capacities of Gundelia tournefortii L. extracts and inhibition on glutathione-S-transferase activity. Food Chem. 100:1249-1253.   DOI   ScienceOn
44 Galati, G. and P. J. O'Brien. 2004. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radic. Biol. Med. 37:287-303   DOI   ScienceOn
45 Cotgreave, I. A. and R. G. Gerdes. 1998. Recent trends in glutathione biochemistry-glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation? Biochem. Biophys. Res. Commun. 242:1-9.   DOI   ScienceOn
46 Das, S. K. and D. M. Vasudevan. 2005. Biochemical diagnosis of alcoholism. Indian J. Clin. Biochem. 20:35-42
47 Fielding, J. F. and P. E. Fielding. 1995. Molecular physiology of reverse cholesterol transport. J. Lipid Res. 36:211-228.
48 Galipalli, S., K. M. Gadiyaram, B. Kouakou, T. H. Terrill and G. Kannan. 2004. Physiological responses to preslaughter transportation stress in Tasco-supplemented Boer goats. SA J. Anim. Sc. 34:92-94.
49 Anthony, M. S., T. B. Clarkson and J. K. Williams. 1998. Effects of soy isoflavones on atherosclerosis: potential mechanism. Am. J. Clin. Nutr. 68:1390S-1393S.
50 Aurousseau, B. 2002. Oxygen radicals in farm animals. Physiological effects and consequences on animal products. Prod. Anim. 15:67-82.
51 Cereser, C., J. Guichard, J. Drai, E. Bannier, I. Garcia, S. Boget, P. Parvaz and A. Revol. 2001. Quantitation of reduced and total glutathione at the femtomole level by high-performance liquid chromatography with fluorescence detection: application to red blood cells and cultured fibroblasts. J. Chromatogr. B, Biomed. Sci. Appl. 752:123-132.   DOI   ScienceOn
52 Chai, Y. C., S. S. Ashraf, K. Rokutan, R. B. Jr. Johnston and J. A. Thomas. 1994. S-thiolation of individual human neutrophil proteins including actin by stimulation of the respiratory burst: evidence against a role for glutathione disulfide. Arch. Biochem. Biophys. 310:273-281.   DOI   ScienceOn
53 Chang, C. K., C. Y. Tsai, L. S. Lin, S. B. Lou, S. S. Liao and J. T. Cheng. 1997. Change of superoxide dismutase (SOD) mRNA and activity in response to hypoxic stress in cultured Wistar rat glioma cells. Neurosci. Lett. 232:115-118.   DOI   ScienceOn
54 Tang, J., C. Faustman, S. Lee and T. A. Hoagland. 2003. Effect of glutathione on oxymyoglobin oxidation. J. Agric. Food Chem. 51:1691-1695.   DOI   ScienceOn
55 Zhang, K. and N. P. Das. 1994. Inhibitory effects of plant polyphenols on rat liver glutathione S-transferases. Biochem. Pharmacol. 47:2063-2068.   DOI   ScienceOn
56 Zhang, K., E. B. Yang, W. Y. Tang, K. P. Wong and P. Mack. 1997. Inhibition of glutathione reductase by plant polyphenols. Biochem. Pharmacol. 54:1047-1053.   DOI   ScienceOn
57 Zhong, R. Z., C. Y. Tan, X. F. Han, S. X. Tang, Z. L. Tan and B. Zeng. 2009. Effect of dietary tea catechins supplementation in goats on the quality of meat kept under refrigeration. Small Rumin. Res. 87:122-125.   DOI   ScienceOn
58 Tachibana, H., K. Koga, Y. Fujimura and K. Yamada. 2004. A receptor for green tea polyphenol EGCG. Nat. Struct. Mol. Biol. 11:380-381.   DOI   ScienceOn
59 Tan, C. Y., R. Z. Zhong, Z. L. Tan, X. F. Han, S. X. Tang, W. J. Xiao, Z. H. Sun and M. Wang. 2010. Dietary inclusion of tea catechins changes fatty acid composition of muscle in goats. Lipids, DOI:10.1007/S11745-010-3477-1.   DOI
60 Tang, S. Z., S. Y. Ou, X. S. Huang, W. Li, J. P. Kerry and D. J. Buckley. 2006. Effects of added tea catechins on color stability and lipid oxidation in minced beef patties held under aerobic and modified atmospheric packaging conditions. J. Food Eng. 77:248-253.   DOI   ScienceOn
61 Tzeng, W. F., T. J. Chiou, C. P. Wang, J. L. Lee and Y. H. Chen. 1994. Cellular thiols as a determinant of responsiveness to menadione in cardiomyocytes. J. Mol. Cell. Cardiol. 26:889-897.   DOI   ScienceOn
62 Vinson, J. A., Y. A. Dabbagh, M. M. Serry and J. Jang. 1995. Plant flavonoids, especially tea flavonols, are powerful antioxidants using an in vitro oxidation model for heart disease. J. Agri. Food Chem. 43:2800-2802.   DOI
63 Winterbourn, C. C. and D. Metodiewa. 1994. The reaction of superoxide with reduced glutathione. Arch. Biochem. Biophys. 314:284-290.   DOI   ScienceOn
64 Yang, C. S., X. Wang, G. Lu and S. C. Picinich. 2009. Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat. Rev. Cancer. 9:429-439.   DOI   ScienceOn