Dietary Supplementation with Acanthopanax senticosus Extract Modulates Gut Microflora in Weaned Piglets
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Yin, Fugui
(Laboratory of Animal Nutrition and Human Health and Key Laboratory of Subtropical Agro-ecology, Institute of Subtropical Agriculture, the Chinese Academy of Sciences)
Yin, Yulong (Laboratory of Animal Nutrition and Human Health and Key Laboratory of Subtropical Agro-ecology, Institute of Subtropical Agriculture, the Chinese Academy of Sciences) Kong, Xiangfeng (Laboratory of Animal Nutrition and Human Health and Key Laboratory of Subtropical Agro-ecology, Institute of Subtropical Agriculture, the Chinese Academy of Sciences) Liu, Yulan (Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University) He, Qinghua (Laboratory of Animal Nutrition and Human Health and Key Laboratory of Subtropical Agro-ecology, Institute of Subtropical Agriculture, the Chinese Academy of Sciences) Li, Tiejun (Laboratory of Animal Nutrition and Human Health and Key Laboratory of Subtropical Agro-ecology, Institute of Subtropical Agriculture, the Chinese Academy of Sciences) Huang, Ruilin (Laboratory of Animal Nutrition and Human Health and Key Laboratory of Subtropical Agro-ecology, Institute of Subtropical Agriculture, the Chinese Academy of Sciences) Hou, Yongqing (Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University) Shu, Xugang (Guangzhou Tanke Industry Co. Ltd.) Tan, Liangxi (Guang An Biological Technique Company) Chen, Lixiang (Guang An Biological Technique Company) Gong, Jianhua (Guelph Food Research, Agriculture and Agri-Food Canada) Kim, Sung Woo (Department of Animal Science, North Carolina State University) Wu, Guoyao (Department of Animal Science, Texas A&M University) |
1 | Yang, Y. X., Y. G Kim, J. D. Lohakare, J. H. Yun, J. K. Lee, M. S. Kwon, J. I. Park, J. Y. Choi and B. J. Chae. 2007b. Comparative efficacy of different soy protein sources on growth performance, nutrient digestibility and intestinal morphology in weaned pigs. Asian-Aust. J. Anim. Sci. 20:775-767. 과학기술학회마을 DOI |
2 | Gong, J. H., R. J. Forster, H. Yu, J. R. Chambers, P. M. Sabour, R. Wheatcroft and S. Chen. 2002b. Diversity and phylogenetic analysis of bacteria in the mucosa of chicken ceca and comparision with bacteria in the cecal lumen. FEMS Microbiol. Lett. 208(1): 1-7. DOI ScienceOn |
3 | Grandlic, C. J., I. Geib, R. Pilon and T. R. Sandrin. 2006. Lead pollution in a large, prairie-pothole lake (Rush Lake, WI, USA): Effects on abundance and community structure of indigenous sediment bacteria. Environ. Pollut. 144: 119-126. DOI ScienceOn |
4 | Fan, M. Z., T. J. Li, Y. L. Yin, R. J. Fang, Z. Y. Tang, Z. P. Hou, R. L. Huang, Z. Y. Deng, H. Y. Zhong, R. G. Zhang, J. Zhang, B. Wang and H. Schulze. 2005. Effect of phytase supplementation with two levels of phosphorus diets on ile al and faecal digestibilities of nutrients and phosphorus, cal cium, nitrogen and energy balances in growing pigs. Anim. Sci. 81:67-75. |
5 | Frydendahl, K. 2002. Prevalence of serogroups and virulence genes in Escherichia coli associated with postweaning diarrhea and edema disease in pigs and a comparison of diagnostic approaches. Vet. Microbiol. 85: 169-182. DOI ScienceOn |
6 | Gillan, D. C., A. G. Speksnijder, G. Zwart and C. de Ridder. 1998. Genetic diversity in the biofilm covering Montacuta ferruginosa (Mollusca, Bivalvia) as evaluated by denaturing gradient gel electrophoresis analysis and cloning of PCR-amplified gene fragments coding for 16S rRNA. Appl. Environ. Microb.64:3464-3472. |
7 | Zhu, W. Y., B. A. Williams and A. Akkermans. 2000. Development of the microbial community in weaning piglets. Reprod. Nutr. Develop. 40:180-186. |
8 | Zhou, J., B. C. Wang and Y. Wang. 2005. Determination and evaluation of saccharides content in extract of herb a spirodelae seu lenmae polysaccharides. J. Chongqing Univ. (Natural Science Edition) 28: 111-114. |
9 | Yoon, T. J., Y. C. Yoo and S. W. Lee. 2004. Anti-metastatic activity of acanthopanax senticosus extract and its possible immunological mechanism of action. J. Ethnopharmacol. 93(23):247-253. DOI ScienceOn |
10 | Deng, Ze-Yuan, Jin-Wu Zhang, Guo-Yao Wu, Yulong Yin, Zheng Ruan, Tie-Jun Li, Wu-Ying Chu, Xiang-Feng Kong, You-Ming Zhang, Ya-Wei Fan, Rong Liu, Rui-Lin Huang. 2007. Dietary supplementation with polysaccharides from Semen cassiae enhances immunoglobulin production and interleukin gene expression in early-weaned piglets. Journal of the Science of Food and Agriculture. 87: 1868-1873. DOI ScienceOn |
11 | Dong, G. Z. and J. R. Pluske. 2007. The low feed intake in newly-weaned pigs: problems and possible Solutions. Asian-Aust. J. Anim. Sci. 20:440-445. 과학기술학회마을 DOI |
12 | AOAC. 2003. Official Methods of Analysis, 17th Edition. Association of Official Analytical Chemists, Arlington, VA. |
13 | Apajalahti, J. and M. R. Bedford. 1998. Nutritrion effects on the micro flora of the GI tract. Proc. 19th Western Nutrition Conference, Department of animal and poultry science, University of Saskatchewan, Saskatoon, Canada. pp. 60-68. |
14 | Bent, S., L. Xu, L. Y. Lui, M. Nevitt, E. Schneider, G. Tian, S. Guo and S. Cummings. 2003. A randomized controlled trial of a Chinese herbal remedy to increase energy, memory, sexual function, and quality of life in elderly adults in Beijing. Am. J. Med. 115(6):441-447. DOI ScienceOn |
15 | Yin,Y.-L., Z. R. Tang, Z. H. Sun, Z. Q. Liu, T. J. Li, R. L. Huang, Z. Ruan, Z. Y. Deng, B. Gao, L. X. Chen, G. Y. Wu and S. W. Kim. 2008. Effect of Galacto-mannan-oligosaccharides or chitosan supplementation on cytoimmunity and humoral immunity response in early-weaned piglets. Aust. J. Anim. Sci. 21:723-731. DOI |
16 | Blecha, F. and B. Charley. 1990. Rationale for using immunopotentiators in domestic food animals. Immunomodulation in domestic food animals (Ed. F. Blecha and B. Charley). Academic Press, San Diego, CA. pp. 3-19. |
17 | Gong, J. H., R. J. Forster, H. Yu, J. R. Chambers, R. Wheatcroft, P. M. Sabour and S. Chen. 2002a. Molecular analysis of bacterial populations in the ileum of broiler chickens and comparison with bacteria in the cecum. FEMS Microbiol. Ecol. 41:171-179. DOI ScienceOn |
18 | Cai, S. F., H. Y. Jiang and Y. P. Ou. 2000. Study on organic acid content in different processed products of fructus crataegi. Chinese Traditional Patent Med. 22(12):841-842. |
19 | Wang, S., Y. T. Jia and Y. Y. Sun. 1996. Study on quantitive determination of flavonoids in the flavonoids of the composite Chinese material medica preparations. WCJ-PS. 11 (2):95-96. |
20 | Yao Kang, Yu-Long Yin, Wuyin Chu, Zhiqiang Liu, Dun Deng, Tiejun Li, Ruilin Huang, Jianshe Zhang, Bie Tan, Wence Wang and Guoyao Wu. 2008. Dietary arginine supplementation increases mTOR signaling activity in skeletal muscle of neonatal pigs. J. Nutr. 138:867-872. DOI |
21 | Hana, S. B., Y. D. Yoona, H. J. Alma, H. S. Leeb, C. W. Leea, W. K. Yoona, S. K. Parka and H. M. Kima. 2003. Toll-like receptor-mediated activation of B cells and macrophages by polysaccharide isolated from cell culture of Acanthopanax senticosus. International Immunopharmacology 3: 1301-1312. DOI ScienceOn |
22 | Kong, X. F., G. Y. Wu, Y. L. Yin, H. J. Liu, F. G. Yin, T. J. Li, R. L. Huang, P. Kang, F. F. Xing, M. Z. Fan, C. B. Yang and Q. H. He. 2007a. Dietary supplementation with Chinese herbal ultrafine powder enhances cellular and humorl immunity in early-weaned piglets. Livest. Sci. 108:94-98. DOI ScienceOn |
23 | Hou Zheu-Ping, Yu-Long Yin, Rui-Lin Huang, Tie-Jun Li, Rongqing Hou, Yulan Liu, Xin Wu, Zhiqiang Liu, Wence Wang, Hua Xiong, Guo-yao Wu and Liang-xi Tan. 2008. Rice protein concentrate partially replaces dried whey in the diet for early-weaned piglets and improves their growth performance. J. Sci. Food Agric. 88:1187-1193. DOI ScienceOn |
24 | Huang, R. L., Y. L. Yin, M. X. Li, G. Y. Wu, T. J. Li, L. L. Li and Y. M. Guo. 2007. Dietary oligochitosan supplementation enhances immune status of broilers. J. Sci. Food Agr. 87:153-159. DOI ScienceOn |
25 | Huang, X. L., J. Y. Zhu and H. Hu. 1998. Function of acanthopanax senticosides in enhancing the immunity of mice. Journal of Sichuan Teachers College (Natural Science) 19(2): 201-203 |
26 | Kong, X. F., G. Y. Wu, Y. P. Liao, Z. P. Hou, H. J. Liu, F. G. Yin, T. J. Li, R. L. Huang, Y. M. Zhang and Y. L. Yin. 2007b. Effects of Chinese herbal ultra-fine powder as a dietary additive on growth performance, serum metabolites and intestinal health in early-weaned piglets. Livest. Sci. 108:272-275. DOI ScienceOn |
27 | Kong, X. F., Y. L. Yin, G. Y. Wu, Y. Q. Hou, H. J. Liu, F. G. Yin, T. J. Li, R. L. Huang, Z. Ruan, H. Xiong, Z. Y. Deng, M. Y. Xie, Y P. Liao, L. X. Chen and S. W. Kim. 2007c. Dietary supplementation with acanthopanax senticosus extract modulates cellular and humoral immunities in weaned piglets. Asian-Aust. J. Anim. Sci. 20:1453-1461. DOI |
28 | Li T.-J., Q.-Z. Dai, Y-L. Yin, J. Zhanga, R.-L. Huanga, Z. Ruana, Z. Denga and M. Xie. 2008. Dietary starch sources affect net portal appearance of amino acids and glucose in growing pigs. Anim.2:723-729. |
29 | McGlone, J. and W. Pond. 2003. In Pig Production: biological principles and applications. Delmar Learning, Inc., Clifton Park., NY |
30 | Li, X. L. and A. G. Zhou. 2007. Preparation of polysaccharides from acanthopanax senticosus and its inhibition against irradiation-induced injury of rat. Carbohydrate Polymers 67: 219-226. DOI ScienceOn |
31 | King, R. H., J. L. Dividich and F. R. Dunshea. 1999. Lactation and neonatal growth. A quantitative biology of the pig (Ed. I. Kyriazakis), CABI publishing, CAB International, Wallingford, UK. pp. 155-180 |
32 | Lee, S., D. S. Shin and K. B. Oh. 2003. Antibacterial compounds from the leaves of acanthopanax senticosus. Arch. Pharm. Res. 26(1):40-42. DOI ScienceOn |
33 | Li, M. Y., G. H. Zhou, X. L. Xu, C. B. Li and W. Y. Zhu. 2006. Changes of bacterial diversity and main flora in chilled pork during storage using PCR-DGGE. Food Microbiol. 23:607-611. DOI ScienceOn |
34 | Han, K. N., I. K. Kwon, J. D. Lohakare, S. Heo and B. J. Chae. 2007. Chito-oligosaccharides as an alternative to antimicrobials in improving performance, digestibility and microbial ecology of the gut in weanling pigs. Asian-Aust. J. Anim. Sci. 20:556-561 과학기술학회마을 DOI |
35 | Han, S. B., Y. D. Yoon and H. J. Ahn. 2003. Toll-like receptormediated activation of B cells and macrophages by polysaccharide isolated from cell culture of acanthopanax senticosus. Int. Immunopharmacol. 3(9):1301-1312. DOI ScienceOn |
36 | Parente, E., M. Martuscelli, F. Gardini, S. Grieco, M. A. Crudelel and G. Suzzi. 2001. Evolution of microbial populations and biogenic amine production in dry sausages produced in Southern Italy. J. Appl. Microbiol. 90: 882-891. DOI ScienceOn |
37 | Simpson, J. M., V. J. McCracken, H. R. Gaskin and R. I. Mackie. 2000. Denaturing gradient gel electrophoresis analysis of 16S ribosomal DNA amplicons to monitor changes in faecal bacterial populations of weaning pigs after introduction of Lactobacillus reuteri strain MM53. Appl. Environ. Microb. 66: 4705-4714. DOI ScienceOn |
38 | Suau, A., R. Bonnet, M. Sutren, J. Godon, G. Gibson, M. Collins and J. Dore. 1999. Direct analysis of genes encoding 16S rRNA from complex commnnities reveals many novel molecular species within the human gut. Appl. Environ. Microb. 65:4799-4807. |
39 | Nubel, U., B. Engelen, A. Felske, J. Snaidr, A. Wieshuber, R. I. Amann, W. Ludwig and H. Backhaus. 1996. Sequence heterogeneities of genes encoding 16S rRNAs in Paenibacillus polymyxa detected by temperature gradient gel electrophoresis. J. Bacteriol. 178:5636-5643. DOI |
40 | Peng, Z. and C. Y. Bang. 2006. Small molecule micro arrays for drug residue detection in foodstuffs. J. Agric. Food Chem. 54: 6978-6983. DOI ScienceOn |
41 | Muyzer, G. and K. Smalla. 1998. Application of denaturing gradient gel electrophoresis (DGGE) and temperature gradient gel electrophoresis (TGGE) in microbial ecology. Antonie Van. Leeuwenhoek 73:127-141. DOI ScienceOn |
42 | Nabuurs, M. J. A. 1995. Microbiological, structural and functional changes of the small intestine of pigs at weaning. Pig News Inform. 16:93-97. |
43 | NRC. 1998. Nutrient Requirements of Swine. 10th ed. Natl. Acad. Press. Washington, DC. |
44 | Wu, G. Y, S. A. Meier and D. A. Knabe. 1996. Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. J. Nutr. 126:2578-2584. DOI |
45 | Liang, L. J., Y. Cai and S. L. Liang. 2006. Experimental research of extract of acathopancix senticosides in anti-tumor action. Lishizhen Medicine and Materia Medica Research 17(7): 1187-1188. |
46 | Wang, Z., J. Lin and Z. Zhang. 2003. In vivo anti-inflammatory and antinociceptive effects of liriodendrin isolated from the stem bark of acanthopanax senticosus. Zhong Yao Cai. 26: 603-606. |
47 | Wu, G. Y, D. A. Knabe and S. W. Kim. 2004. Arginine nutrition in neonatal pigs. J. Nutr. 134:2783-2390. DOI |
48 | Touchette, K. J., J. A. Carroll, G. L. Allee, R. L. Matteri, C. J. Dyer, L. A. Beausang and M. E. Zannelli. 2002. Effect of spray-dried plasma and lipopolysaccharide exposure on weaned pigs: J. Effects on the immune axis of weaned pigs. J. Anim. Sci. 80: 494-501. DOI |
49 | Walter, J., G. W. Tannock, A. Tilsala-Timisjarvi. S. Rodtong, D. M. Loach, K. Munro and T. Alatossava. 2000. Detection and identification of gastrointestinal lactobacillus species by using denaturing gradient gel electrophoresis and species-specific PCR primers. Appl. Environ. Microb. 66:297-303. DOI ScienceOn |
50 | Wang Junjun, Lixiang Chen, Peng Li, Xilong Li, Huaijun Zhou, Fenglai Wang, Defa Li, Yulong Yin and Guoyao Wu. 2008. Gene expression is altered in piglet small intestine by weaning and dietary glutamine supplementation. J. Nutr. 138: 1025-1032. DOI |
51 | Tang, Zhi-Ru, Yu-Long Yin, Charles M. Nyachoti, Rui-Lin Huang, TieJun Li, Chengbo Yang, Xiao-jian Yang, Joshua Gong, Jiang Peng, De-Sheng Qi, Jian-Jun Xing, Zhi-Hong Sun and Ming Z. Fan. 2005. Effect of dietary supplementation of chitosan and galacto-mannan-oligosaccharide on serum parameters and the insulin-like growth factor-I mRNA expression in early-weaned piglets. Domestic Animal Endocrinology 28:430-441. DOI ScienceOn |
52 | Yin, F. G., Y. L. Liu, Y. L. Yin, X. F. Kong, R. L. Huang, T. J. Li, G. Y. Wu and Yongqing Hou. 2008. Dietary supplementation with Astragalus polysaccharide enhances ileal digestibilities and serum concentrations of amino acids in early weaned piglets. Amino Acids.DOI 10.1007/s00726-008-0142-6 DOI |
53 | Simpson, J. M., V. J. McCracken, B. A. White, H. R. Gaskins and R. I. Mackie. 1999. Application of denaturant gradient gel electrophoresis for the analysis of the porcine gastrointestinal microbiota. J. Microbiol. Meth. 36:167-179. DOI ScienceOn |
54 | Yi, J. M., S. H. Hong, J. H. Kim, H. K. Kim, H. J. Song and H. M. Kim. 2002. Effect of acanthopanax senticosus stem on mast cell-dependent anaphylaxis. J. Ethnopharmacol. 79:347-352. DOI ScienceOn |
55 | Zcetendal, E. G, A. D. L. Akkermans and W. M. de Vos. 1998. Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl. Environ. Microbiol. 64: 3854-3859. |
56 |
Yin, Y.-L, S. K. Baidoo, H. Schulze and P. H. Simmins. 2001. Effect of supplementing diets containing hulless barley varieties having different levels of non-starch polysaccharides with |
57 | Yang, H., A. Li, Y. L. Yin, T. J. Li, Z. R. Wang, G. Wu, R. L. Huang, X. F. Kong, C. B. Yang, P. Kang, J. Deng, S. X. Wang, B. Tan, Q. Hu, F. F. Xing, X. Wu, Q. H. He, K. Yao, Z. Liu, Z. R. Tang, F. G. Yin, Z. Y Deng, M. Y Xie and M. Z. Fan. 2007a. True phosphorus digestibility and endogenous phosphorus outputs associated with brown rice for weanling pigs measured by the simple linear regression analysis technique forweanling pigs. Anim. 1:213-220. DOI ScienceOn |
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