Browse > Article
http://dx.doi.org/10.5713/ajas.2008.70692

Effects of Chromium Picolinate Supplementation on Growth Hormone Secretion and Pituitary mRNA Expression in Finishing Pigs  

Wang, M.Q. (Animal Science College of Zhejiang University, Key Laboratory of Molecular Animal Nutrition Ministry of Education)
He, Y.D. (Animal Science College of Zhejiang University, Key Laboratory of Molecular Animal Nutrition Ministry of Education)
Xu, Z.R. (Animal Science College of Zhejiang University, Key Laboratory of Molecular Animal Nutrition Ministry of Education)
Li, W.F. (Animal Science College of Zhejiang University, Key Laboratory of Molecular Animal Nutrition Ministry of Education)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.21, no.7, 2008 , pp. 1033-1037 More about this Journal
Abstract
The purpose of the present study was to investigate the effects of chromium picolinate (CrPic) on growth hormone (GH) secretion and pituitary GH mRNA expression in finishing pigs. Forty eight crossbred pigs with an initial body weight of 65.57 kg (SD = 1.05) were blocked by body weight and randomly assigned to two treatments with three replicates. Each group was fed the diet supplemented with or without $200{\mu}g/kg$ chromium from CrPic for 40 days. The results showed that average daily gain of pigs was increased by 9.84% (p<0.05), and longissimus muscle area was increased by 17.29% (p<0.05) with the supplementation of CrPic. The results of GH dynamic secretion showed that supplemental CrPic increased the mean level and peak value of GH by 36.58% (p<0.05) and 26.60% (p<0.05), respectively, while there was no significant effect on basal value, peak amplitude and peak duration. Pituitary mRNA expression of GH was not significantly influenced by supplemental CrPic. These results indicated that CrPic increased pigs GH secretion without change of pituitary GH mRNA expression.
Keywords
Chromium Picolinate; Pigs; Growth Hormone;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 2  (Related Records In Web of Science)
Times Cited By SCOPUS : 2
연도 인용수 순위
1 Roginski, E. E. and W. Mertz. 1969. Effects of chromium (III) supplementation on glucose and amino acid metabolism in rats fed a low protein diet. J. Nutr. 97:525-530.   DOI
2 Merriam, G. R. and K. W. Wachter. 1982. Algorithms for the study of episodic hormone secretion. Am. J. Physiol. Endocrinol. Metab. 243:E310-E318.   DOI
3 Wang, M. Q. and Z. R. Xu. 2004. Effect of chromium nanoparticle on growth performance, carcass characteristics, pork quality and tissue chromium in finishing pigs. Asian-Aust. J. Anim. Sci. 17:1118-1122.   과학기술학회마을   DOI
4 Wang, M. Q., Z. R. Xu, L.Y. Zha and M. D. Lindemann. 2007. Effects of chromium nanocomposite supplementation on blood metabolites, endocrine parameters and immune traits in finishing pigs. Anim. Feed Sci. Technol. 139:69-80.   DOI   ScienceOn
5 SAS (Statistical Analysis System Inc.). 1989. SAS/STAT User's Guide. Version 6. SAS Institute Inc., Cary, NC.
6 Okada, S., H. Tsukada and H. Ohba. 1984. Enhancement of nuclear RNA synthesis by chromium (III) in regenerating rat liver. J. Inorg. Biochem. 21:113-124.   DOI   ScienceOn
7 Schram, E., S. Moore and E. W. Bigwood. 1954. Chromatographic determination of cystine as cystic acid. Biochem. J. 57:33-37.   DOI
8 Shelton, J. L., R. L. Payne, S. L. Johnston, T. D. Bidner, L. L. Southern, R. L. Odgaard and T. G. Page. 2003. Effect of chromium propionate on growth, carcass traits, pork quality, and plasma metabolites in growing-finishing pigs. J. Anim. Sci. 81:2515-2524.   DOI
9 Okada, S., M. Taniyama and H. Ohba. 1982. Mode of enhancement in ribonucleic acid synthesis directed by chromium (III)-bound deoxyribonucleic acid. J. Inorg. Biochem. 17:41-49.   DOI   ScienceOn
10 Okada, S., H. Tsukada and M. Tezuka. 1989. Effect of chromium (III) on nucleolar RNA synthesis. Biol. Trace Elem. Res. 21:35-39.   DOI
11 Page, T. G., L. L. Southern, T. L. Ward and D. L. Jr. Thompson. 1993. Effect of chromium picolinate on growth and serum and carcass traits of growing-finishing pigs. J. Anim. Sci. 71:656-662.   DOI
12 National Research Council (NRC). 1997. The role of chromium in animal nutrition. National Academy Press, Washington, DC. p. 80.
13 National Research Council (NRC). 1998. Nutrient Requirements of Swine, 10th edn. National Academy Press, Washington, DC.
14 Okada, S., M. Susuki and H. Ohba. 1983. Enhancement of ribonucleic acid synthesis by chromium (III) in mouse liver. J. Inorg. Biochem. 19:95-103.   DOI   ScienceOn
15 Xi, G., Z. R. Xu, S. H. Wu and S. J. Chen. 2001. Effect of chromium picolinate on growth performance, carcass characteristics, serum metabolites and metabolism of lipid in pigs. Asian-Aust. J. Anim. Sci. 14:258-264.   DOI
16 Lien, T. F., K. H. Yang and K. J. Lin. 2005. Effects of chromium propionate supplementation on growth performance, serum traits and immune in weaned pigs. Asian-Aust. J. Anim. Sci. 18:403-409.   과학기술학회마을   DOI
17 Lindemann, M. D., C. M. Wood, A. F. Harper, E. T. Kornegay and R. A. Anderson. 1995. Dietary chromium picolinate additions improve gain:feed and carcass characteristics in growingfinishing pigs and increase litter size in reproducing sows. J. Anim. Sci. 73:457-465.   DOI
18 Matthews, J. O., A. D. Higbie, L. L. Southern, D. F. Coombs, T. D. Bidner and R. L. Odgaard. 2003. Effect of chromium propionate and metabolizable energy on growth, carcass traits, andpork quality of growing-finishing pigs. J. Anim. Sci. 81:191-196.   DOI
19 Ward, T. L., L. L. Southern and R. A. Anderson. 1995. Effect of dietary chromium source on growth, carcass characteristics, and plasma metabolite and hormone concentrations in growing-finishing swine. J. Anim. Sci. 73(Suppl.):189(Abstr.).
20 Steele, N. C., T. G. Althen and L. T. Frobish. 1977. Biological activity of glucose tolerance factoring swine. J. Anim. Sci. 45:1341-1345.   DOI
21 Boleman, S. L., S. J. Boleman, T. D. Bidner, L. L. Southern, T. L. Ward, J. E. Pontif and M. M. Pike. 1995. Effect of chromium picolinate on growth, body composition, and tissue accretion in pigs. J. Anim. Sci. 73:2033-2042.   DOI
22 Bunting, L. D., J. M. Fernandez, D. L. Jr. Thompson and L. L. Southern. 1994. Influence of chromium picolinate on glucose usage and metabolic criteria in growing Holstein calves. J. Anim. Sci. 72:1591-1599.   DOI
23 AOAC. 1995. Official Methods of Analysis. 16th ed. Assoc. Off. Anal. Chem. Arlington, VA.
24 Evock-Clover, C. M., M. M. Polansky, R. A. Anderson and N. C. Steele. 1993. Dietary chromium supplementation with or without somatotropin treatment alters serum hormones and metabolites in growing pigs without affecting growth performance. J. Nutr. 123:1504-1512.   DOI
25 Guan, X., J. J. Matte, P. R. Ku, J. L. Snow, J. L. Burton and N. L. Trottier. 2000. High chromium yeast supplementation improves glucose tolerance in pigs by decreasing hepatic extraction of insulin. J. Nutr. 130:1274-1279.   DOI
26 Anderson, R. A. 1987. Chromium. In: Trace elements in human and animal nutrition (5th Ed.) (Ed. W. Mertz). p. 225. Academic Press, San Diego, CA.
27 Barb, C. R., R. R. Kraeling and G. B. Rampacek. 2002. Metabolic regulation of the neuroendocrine axis in pigs. Reprod. Suppl. 59:203-217.
28 Mooney, K. W. and G. L. Cromwell. 1995. Effects of dietary chromium picolinate supplementation on growth, carcass characteristics, and accretion rates of carcass tissues in growing-finishing swine. J. Anim. Sci. 73:3351-3357.   DOI
29 Mooney, K. W. and G. L. Cromwell. 1996. Effects of chromium picolinate on growth performance and tissue accretion in pigs with different lean gain potential. J. Anim. Sci. 74 (Suppl.): 65 (Abstr.).
30 Mooney, K. W. and G. L. Cromwell. 1997. Efficacy of chromium picolinate and chromium chloride as potential modifiers in swine. J. Anim. Sci. 75:2661-2671.   DOI