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http://dx.doi.org/10.5713/ajas.2008.70314

Associations between Alu I Polymorphism in the Prolactin Receptor Gene and Reproductive Traits of Slovak Large White, White Meaty and Landrace Pigs  

Omelka, R. (Department of Botany and Genetics, Constantine the Philosopher University)
Martiniakova, M. (Department of Zoology and Anthropology, Constantine the Philosopher University)
Peskovicova, D. (Institute for Animal Breeding, Slovak Agricultural Research Center - Research Institute for Animal Production)
Bauerova, M. (Department of Botany and Genetics, Constantine the Philosopher University)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.21, no.4, 2008 , pp. 484-488 More about this Journal
Abstract
We investigated the effect of the prolactin receptor gene (PRLR) on total number of born (TNB), number of born alive (NBA) and number of weaned (NW) piglets in Large White (LW), White Meaty (WM) and Landrace (L) sows from six Slovak breeding farms. The frequency of A allele was 0.48, 0.49 and 0.47 in LW, WM and L, respectively. We found numerous highly significant effects of PRLR locus on TNB ($p{\leq}0.01$; $p{\leq}0.05$) in all tested breeds. The most marked difference of +$1.31{\pm}0.45pigs/L$ was found between AA and BB genotypes in WM. Within the other breeds the difference between the homozygous genotypes reached up to +$0.94{\pm}0.3$ and +$1.21{\pm}0.19$ pigs per litter in LW and L, respectively. We also identified significant differences between AA and AB genotypes related to TNB in L. Similarly NBA, as well as NW traits were significantly affected ($p{\leq}0.01$; $p{\leq}0.05$) by the genotype just in LW and L. The homozygous genotype AA was favourable in all breeds and traits. Our results showed the possibility of PRLR utilization in marker-assisted selection within breeding programs to increase reproductive traits of pigs in Slovakia.
Keywords
Prolactin Receptor Gene; PRLR; Reproductive Traits; Litter Size; Pigs;
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1 Ormandy, C. J., A. Camus, J. Barra, D. Damotte, B. Lucas, H. Buteau, M. Edery, N. Brousse, C. Babinet, N. Binart and P. A. Kelly. 1997. Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse. Genes Dev. 11:167-178.   DOI   ScienceOn
2 Kelly, P. A., J. Djiane, M. C. Postel-Vinay and M. Edery. 1991. The prolactin/growth hormone receptor family. Endocr. Rev. 12:235-251.   DOI   ScienceOn
3 Kmiec, M. and A. Terman. 2006. Associations between the prolactin receptor gene polymorphism and reproductive traits of boars. J. Appl. Genet. 47:139-141.   DOI   ScienceOn
4 Lin, C. L., S. Ponsuksili, E. Tholen, D. G. Jennen, K. Schellander and K. Wimmers. 2006. Candidate gene markers for sperm quality and fertility of boar. Anim. Reprod. Sci. 92:349-363.   DOI   ScienceOn
5 Xiong, Y., S. Zhang, C. Den, S. Xiao, J. Xu, Y. Xia, X. Liu, C. Wang and S. Sun. 2004. FSHR gene mutation and its effect on litter size in pigs. Asian-Aust. J. Anim. Sci. 17:179-182.   과학기술학회마을   DOI
6 Xu, N. Y., S. Q. Zhang and S. H. Peng. 2003. Investigation on the distribution and their effects on reproduction traits of three major genes in Jinhua pigs. Yi Chuan Xue Bao. 30:1090-1096.
7 Rothschild, M. F., A. L. Vincent, K. Tuggle, G. Evans, T. H. Short, O. I. Southwood, R. Wales and G. S. Plastow. 1998. A mutation in the prolactin receptor gene is associated with increased litter size in pigs. Anim. Genet. 29:69.
8 Drogemuller, C., H. Hamann, J. Krieter, U. Presuhn, J. Wallenburg and O. Distl. 2000. Candidate gene markers connected to litter size in German pigs. 27th Int. Conf. Anim. Genet., Minneapolis. 26.
9 Huang, S. Y., H. L. Song, E. C. Lin, W. C. Lee, J. C. Chiang and H. L. Tsou. 2006. Association of polymorphisms in epidermal growth factor, prostaglandin-endoperoxide synthase 2 and prolactin receptor genes with semen quality in duroc boars. Asian-Aust. J. Anim. Sci. 19:793-798.   과학기술학회마을   DOI
10 Korwin-Kossakowska, A., M. Kamyczek, D. Cieslak, M. Pierzchala and J. Kuryl. 2003. Candidate gene markers for reproductive traits in polish 990 pig line. J. Anim. Breed. Genet. 120:181-191.   DOI   ScienceOn
11 Omelka, R., M. Bauerova, J. Mlynek, B. Buchova, D. Peskovicova and J. Bulla. 2005. Effects of the oestrogen receptor (ESR) gene on reproductive traits of Large White, White Meaty and Landrace pigs. Czech J. Anim. Sci. 50:249-253.
12 Putnova, L., A. Knoll, J. Dvorak and S. Cepica. 2002. A new HpaII PCR-RFLP within the porcine prolactin receptor (PRLR) gene and study of its effect on litter size and number of teats. J. Anim. Breed. Genet. 119:57-63.   DOI   ScienceOn
13 Linville, R. C., D. Pomp, R. K. Johnson and M. F. Rothschild. 2001. Candidate gene analysis for loci affecting litter size and ovulation rate in swine. J. Anim. Sci. 79:60-67   DOI
14 Niu, B. Y., Y. Z. Xiong, S. W. Jiang, F. E. Li, C. Y. Deng, S. H. Ding, W. H. Guo, M. G. Lei, R. Zheng, B. Zuo, D. Q. Xu and J. L. Li. 2006. Oviduct-specific glycoprotein 1 locus is associated with litter size and weight of ovaries in pigs. Asian- Aust. J. Anim. Sci. 19:632-637.   과학기술학회마을   DOI
15 Drogemuller, C., H. Hamann and O. Distl. 2001. Candidate gene markers for litter size in different German pig lines. J. Anim. Sci. 79:2565-2570.   DOI
16 Isler, B. J., K. M. Irvin, M. F. Rothschild and G. J. Evans. 2000. Association between prolactin receptor gene and reproductive components in swine. 27th Int. Conf. Anim. Genet., Minneapolis. 67.
17 Alonso, V., B. A. A. Santana, W. Pirage Jr., L. R. Goulart, H. Diniz, M. F. Machaim and G. S. N. Borges. 2003. Effect of prolactin receptor gene on the qantitative characteristics of economic interest on pigs. Braz. J. Vet. Res. Anim. Sci. 40:366-372.   DOI
18 van Rens, B. T. and T. van der Lende. 2002. Litter size and piglet traits of gilts with different prolactin receptor genotypes. Theriogenol. 57:883-893.   DOI   ScienceOn
19 Chvojkova, Z. and S. Hraska. 2008. Changes in reproductive traits of large white pigs after the estrogen receptor gene-based selection in Slovakia: preliminary results. Asian-Aust. J. Anim. Sci. 21:320-324.   과학기술학회마을   DOI
20 van Rens, B. T., G. J. Evans and T. van der Lende. 2003. Components of litter size in gilts with different prolactin receptor genotypes. Theriogenol. 59:915-926.   DOI   ScienceOn
21 Vincent, A. L., L. Wang, C. K. Tuggle, A. Robic and M. F. Rothschild. 1997. Prolactin receptor maps to pig chromosome 16. Mamm. Genome. 8:793-794.   DOI
22 Vincent, A. L., G. Evans, T. H. Short, O. I. Southwood, G. S. Plastow, C. K. Tuggle and M. F. Rothschild. 1998. The prolactin receptor gene is associated with increased litter size in pigs. Proceedings 6th World Cong. Genet, App. Liv. Prod., Armidale. 27:15-18.
23 Southwood, O. I., T. H. Short, G. S. Plastow and M. F. Rothschild. 1999. A genetic marker for litter size in Landrace-based pig lines. EAAP, Zurich. 5:1.
24 Terman, A. 2005. Effect of the polymorphism of prolactin receptor (PRLR) and leptin (LEP) genes on litter size in Polish pigs. J. Anim. Breed. Genet. 122:400-404.   DOI   ScienceOn
25 $SAS^{\circledR}$ v 8.2. SAS Institute Inc., Cary, USA, 2002.
26 Omelka, R., D. Peskovicova, M. Martiniakova, M. Bauer and M. Bauerova. 2006. Effect of the estrogen receptor (ESR) and ryanodine receptor (RYR1) genes on reproductive traits of Slovak Large White, White Meaty and Landrace pigs. Arch. Tierz. 49:357-362.