Browse > Article
http://dx.doi.org/10.5713/ajas.2005.1379

A Study on Effect of Carrying FecB Gene on Body Weight in Garole and Garole×Malpura Sheep  

Kolte, A.P. (Animal Biotechnology Section and Division of Animal Genetics and Breeding Central Sheep and Wool Research Institute)
Mishra, A.K. (Animal Biotechnology Section and Division of Animal Genetics and Breeding Central Sheep and Wool Research Institute)
Kumar, S. (Animal Biotechnology Section and Division of Animal Genetics and Breeding Central Sheep and Wool Research Institute)
Arora, A.L. (Animal Biotechnology Section and Division of Animal Genetics and Breeding Central Sheep and Wool Research Institute)
Singh, V.K. (Animal Biotechnology Section and Division of Animal Genetics and Breeding Central Sheep and Wool Research Institute)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.18, no.10, 2005 , pp. 1379-1382 More about this Journal
Abstract
High prolificacy in Garole sheep is due to existence of FecB mutation in an autosomal gene, bone morphogenetic protein receptor. The mutation enhances ovulation rate and in turn litter size in Garole sheep. Garole sires were crossed with non-prolific Malpura ewes with the aim to introduce prolificacy into Garole${\times}$Malpura (G${\times}$M) crosses through FecB introgression programme. In the present study, the effect of carrying booroola allele on litter size and live body weight was analyzed. The average litter size at birth was found to be 1.87 and 1.48 in the Garole and the G${\times}$M crosses, respectively. At weaning, 6-month, 9-month and 12-month of age, body weights were not affected by the presence of booroola allele (p>0.05); however, a significant effect (p<0.05) was found on body weight at birth in G${\times}$M crosses. In Garole sheep, no significant effect of FecB was observed on live weights in any age group. The interaction between the genetic group and the FecB genotype was also found to be non-significant.
Keywords
Garole; Garole${\times}$Malpura; Litter Size; Body Weight; FecB Gene;
Citations & Related Records

Times Cited By Web Of Science : 6  (Related Records In Web of Science)
Times Cited By SCOPUS : 7
연도 인용수 순위
1 Elsen, J. M., L. Bodin and J. Thimonier. 1990. Major genes for reproduction in sheep. Second international Booroola workshop. Toulous, France, July 16-18.
2 Fabre, S., A. Pierre, C. Pisselet, P. Mulsant, F. Lecerf, J. Pohl, P. Monget and D. Monniaux. 2003. The Booroola mutation in sheep is associated with an alteration of the bone morphogenetic protein receptor-IB functionality. J. Endocrinol. 177:435-44.   DOI   ScienceOn
3 Sharma, R. C., A. L. Arora, A. K. Mishra, S. Kumar and V. K. Singh. 2004. Breeding prolific Garole with Malpura sheep for increased reproductive efficiency in semi-arid tropics of India. Asian-Aust. J. Anim. Sci. 17:737-742.
4 Sharma, R. C., A. L. Arora, H. K. Narula and R. N. Singh. 1999. Characteristics of Garole sheep in India, Anim. Genet. Reso. Inform. 26:57-64.
5 Willingham, T. D., D. W. Waldron and P. V. Thompson. 2002. Effect of $Fec^B$ allele on birth weight and post-weaning production traits of Rambouillet-Booroola cross wethers. Sheep and Goat, Wool and Mohair CPR 1-6.
6 Smith, P. O. W. S., N. L. Hudson, L. Shaw, D. A. Heath, L. Condell and K. P. Phillips McNatty. 1993. Effects of the Booroola gene (FecB) on body weight, ovarian development and hormone concentarations during fetal life. J. Reprod. Fertil. 98:41-54.
7 Bose, S. and D. N. Moitra. 1995. Bengal breed of sheep in the Sunderbans. Asian Livestock pp. 16-17.
8 Kleeman, D. O., R. W. Ponzoni, J. E. Stafford and R. J. Grimson. 1985. Growth and carcass characters of South Australian Merino and its crosses with the Booroola and Trangie fertility Merino. Aust. J. Expt. Agri. 25:750-757.
9 Visscher, A. H., M. Dijkstra, E. A. Lord, R. Suss, H. J. Rosler, K. Heylen and R. F. Veerkamp. 2000. Maternal and lamb carrier effects of the Booroola gene on food intake, growth and carcass quality of male lambs. Anim. Sci. 71:209-217.
10 Walling, G. A., K. G. Dodds, S. M. Galloway, A. E. Beattie, E. A. Lord, J. M. Lumsden, G. W. Montgomery and J. C. McEwan. 2000. The consequences of carrying the Booroola fecundity (FecB) gene on sheep live weight. Proceed. Br. Soc. Anim. Sci. p. 43.
11 Nimbkar, C., P. M. Ghalsasi, J. F. Maddox, V. C. Pardeshi, M. N. Sainani, V. Gupta and S. W. Walkden-Brown. 2003. Expression of FecB gene in Garole and Crossbred ewes in Maharastra, India. Proceedings of the fifteenth conference of AAABG, Melbourne, Australia. pp. 111-114.
12 Sharma, R. C., A. L. Arora and B. U. Khan. 2001. Garole: A prolific sheep of India. Central Sheep and Wool Research Institute, Avikanagar, Rajasthan-304501.
13 Mishra, A. K., A. L. Arora, S. Kumar, R. C. Sharma and V. K. Singh. 2005. Malpura: A mutton type sheep breed. Central Sheep and Wool Research Institute, Avikanagar, Rajasthan-304501.
14 Wilson, T., X. Y. Wu, J. L. Juengel, I. K. Ross, J. M. Lumsden, E. A. Lord, K. G. Dodds, G. A. Walling, J. C. McEwan, A. R. O’Connell, K. P. McNatty and G. W. Montgomery. 2001. Highly prolific booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulose cells. Biol. Reprod. 64:1225-1235.
15 Davis, G. H., S. M. Galloway, K. I. Ross, M. S. Gregan, J. Ward, V. B. Nimbkar, M. P. Ghalsasi, C. Nimbkar, D. G. Gray, Subandryo, I. Inounu, B. Tiesnamuiti, E. Martyniuk, E. Eythorsdottir, P. Mulsant, F. Lecerf, P. J. Hanrahan, E. G. Bradford and T. Wilson. 2002. DNA tests in prolific sheep from eight countries provide new evidence on origin of the Booroola (FecB) mutation. Biol. Reprod. 66:1869-1874.
16 Ghalsasi, P. M. and B. V. Nimbkar. 1993. The Garole-Microsheep of Bengal, India. Anim. Genet. Reso. Inform. 12:73-79.
17 Bose, S., R. Dutta Gupta and D. N. Moitra. 1999. Reproductive performance of Bengal sheep in Sunderbans. Indian J. Anim. Prod. Mgmt. 15:157-160.
18 Montgomery, G. W., K. P. McNatty and G. H. Davis. 1992. Physiology and molecular genetics of mutations that increase ovulation rate in sheep. Endocrine Reviews. 13:309-320.