1 |
Yang L, Cao X, Yan H, and Wood WC (2003) Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy. Cancer Res 63: 6815-6824
|
2 |
Wu G, Chai J, Suber TL, Wu JW, Du C, Wang X, and Shi Y (2000) Structural basis of IAP recognition by Smac/DIABLO. Nature 408: 1008-1012
DOI
ScienceOn
|
3 |
Hu P, Han Z, Couvillon AD, and Exton JH (2004) Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J Biol Chem 279: 49420-49429
DOI
ScienceOn
|
4 |
Hu S and Yang X (2003) Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. J Biol Chem 278: 10055-10060
DOI
ScienceOn
|
5 |
Huang H, Joazeiro CA, Bonfoco E, Kamada S, Leverson JD, and Hunter T (2000) The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro mono-ubiquitination of caspase 3 and 7. J Biol Chem 275: 26661-26664
DOI
|
6 |
Huh JR, Vernooy SY, Yu H, Yan N, Shi Y, Guo M, and Hay BA (2004) Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization. PLoS Biol 2: 43-53
DOI
ScienceOn
|
7 |
Kelino A, Valanne S, Ulvila J, Kallio J, Myllymaki H, Enwald H, Stoven S, Poidevin m, Ueda R, Hultmark D, Lemaitre B, and Ramet M (2005) Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway. EMBO J 24: 3423-3434
DOI
ScienceOn
|
8 |
Hinds MG, Norton RS, Vaux DL, and Day CL (1999) Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat. Nat Struct Biol 6: 648-651
DOI
ScienceOn
|
9 |
Holcik M, Lefebvre C, Yeh C, Chow T, and Korneluk RG (1999) A new internal ribosome entry site motif potentiates XIAP-mediated cytoprotection. Nat Cell Biol 1: 190-192
DOI
ScienceOn
|
10 |
Wang SL, Hawkins CJ, Yoo SJ, Muller HA, and Hay BA (1999) The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Cell 98: 453-463
DOI
ScienceOn
|
11 |
Wilkinson JC, Wilkinson AS, Scott FL, Csomos RA, Salvesen GS, and Duckett CS (2004) Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs): a caspase-independent mechanism for apoptotic inhibition. J Biol Chem 279: 51082-51090
DOI
ScienceOn
|
12 |
Hay BA, Wassarman DA, and Rubin GM (1995) Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death. Cell 83: 1253-1262
DOI
ScienceOn
|
13 |
Harlin H, Reffey SB, Duckett CS, Lindsten T, and Thompson CB (2001) Characterization of XIAP-deficient mice. Mol Cell Biol 21: 3604-3608
DOI
ScienceOn
|
14 |
Hauser H-P, Bardroff M, Pyrowolakis G, and Jentsch S (1998) A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors. J Cell Biol 141: 1415-1422
DOI
|
15 |
Hawkins CJ, Wang SL, and Hay BA (2000) A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1. Proc Natl Acad Sci USA 96: 2885-2890
DOI
|
16 |
Fraser A, James C, Evan G, and Hengartner M (1999) C. elegans inhibitor of apoptosis protein (IAP homologue BIR-1 plays a conserved role in cytokinesis. Curr Biol 9: 292-301
DOI
ScienceOn
|
17 |
Galvan V, Kurakin AV, and Bredesen DE (2004) Interaction of checkpoint kinase 1 and the X-linked inhibitor of apoptosis during mitosis. FEBS Lett 558: 57-62
DOI
ScienceOn
|
18 |
Geisbrecht ER and Montell DJ (2004) A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration. Cell 118: 111-125
DOI
ScienceOn
|
19 |
Wilson R, Goyal L, Ditzel M, Zachariou A, Baker DA, Agapite J, Steller H, and Meier P (2002) The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. Nat Cell Biol 4: 445-450
DOI
ScienceOn
|
20 |
Wang C-Y, Mayo MW, Korneluk RG, Goeddel DV, and Baldwin AS (1998) NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and cIAP1 and cIAP2 to suppress casapse-8 activation. Science 281: 1680-1683
DOI
ScienceOn
|
21 |
Gesellchen V, Kuttenkeuler D, Steckel M, Pelte N, and Boutros M (2005) An RNA interference screen identifies inhibitor of apoptosis protein 2 as a regulator of innate immune signaling in Drosophila. EMBO Rep 6: 979-984
DOI
ScienceOn
|
22 |
Goyal L, McCall K, Agapite J, Hartwieg E, and Steller H (2000) Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function. EMBO J 19: 589-597
DOI
ScienceOn
|
23 |
Hao Y, Sekine K, Kawabata A, Nakamura H, Ishioka T, Ohata H, Katayama R, Hashimoto C, Zhang X, Noda T, Tsuruo T, and Naito M (2004) Apollon ubiquitinates Smac and caspase-9, and has an essential cytoprotection function. Nat Cell Biol 6: 849-860
DOI
ScienceOn
|
24 |
Dohi T, Okada K, Xia F, Wilford CE, Samuel T, Welsh K, Marusawa H, Zou H, Armstrong R, Matsuzawa S, Salvesen GS, Reed JC, and Altieri DC (2004) An IAP-IAP complex inhibits apoptosis. J Biol Chem 279: 34087-34090
DOI
ScienceOn
|
25 |
Du C, Fang M, Li Y, Li L, and Wang X (2000) SMAC, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102: 33-42
DOI
ScienceOn
|
26 |
Deveraux QL, Takahashi R, Salvesen GS, and Reed JC (1997) X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388: 300-304
DOI
ScienceOn
|
27 |
Vischioni B, Giaccone G, Span SW, Kruyt FAE, and Rodriguez JA (2004) Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2. Exp Cell Res 298: 535-548
DOI
ScienceOn
|
28 |
Ekedahl J, Joseph B, Grigoriev MY, Muller M, Magnusson C, Lewensohn R, and Zhivotovsky B (2002) Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells. Exp Cell Res 279: 277-290
DOI
ScienceOn
|
29 |
Crook NE, Clem RJ, and Miller LK (1993) An apoptosis inhibiting baculovirus gene with a zinc finger like motif. J Virol 67: 2168-2174
|
30 |
Davoodi J, Lin L, Kelly J, Liston P, and MacKenzie AE (2004) Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9. J Biol Chem 279: 40622-40628
DOI
ScienceOn
|
31 |
Chu Z-L, McKinsey TA, Liu L, Gentry JJ, Malim MH, and Ballard DW (1997) Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis cIAP2 is under NFkB control. Proc Natl Acad Sci USA 94: 10057-10062
DOI
|
32 |
Conze DB, Albert L, Ferrick DA, Goeddel DV, Yeh W-C, Mak T, and Ashwell JD (2005) Posttranscriptional downregulation of cIAP2 by the ubiquitin protein ligase cIAP1 in vivo. Mol Cell Biol 25: 3348-3356
DOI
ScienceOn
|
33 |
Vucic D, Stennicke HR, Pisabarro MT, Salvesen GS, and Dixit VM (2000) ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas. Curr Biol 10: 1359-1366
DOI
ScienceOn
|
34 |
Vaux DL and Korsmeyer SJ (1999) Cell death in development. Cell 96: 245-254
DOI
ScienceOn
|
35 |
Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE, Moritz RL, Simpson RJ, and Vaux DL (2000) Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102: 43-53
DOI
ScienceOn
|
36 |
Clem RJ and Miller LK (1993) Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus. J Virol 67: 3730-3738
|
37 |
Clemens MJ, Bushell M, Jeffrey IW, Pain VM, and Morley SJ (2000) Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cells. Cell Death Differ 7: 603-615
DOI
|
38 |
Beltrami E, Plescia J, Wilkinson JC, Duckett CS, and Altieri DC (2004) Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis. J Biol Chem 279: 2077-2084
DOI
ScienceOn
|
39 |
Birkey Reffey S, Wurthner JU, Parks WT, Roberts AB, and Duckett CS (2001) X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling. J Biol Chem 276: 26542-26549
DOI
ScienceOn
|
40 |
Burstein E, Ganesh L, Dick RD, van De Sluis B, Wilkinson JC, Klomp LW, Wijmenga C, Brewer GJ, Nabel GJ, and Duckett CS (2004) A novel role for XIAP in copper homeostasis through regulation of MURR1. EMBO J 23: 244-254
DOI
ScienceOn
|
41 |
Bartke T, Pohl C, Pyrowolakis G, and Jentsch S (2004) Dual role of Bruce as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase. Mol Cell 14: 801-811
DOI
ScienceOn
|
42 |
Uren AG, Beiharz T, O'Connell MJ, and Lithgow T (1999) Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division. Proc Natl Acad Sci USA 96: 10170-10175
DOI
|
43 |
Chai J, Shiozaki E, Srinivasula SM, Wu Q, Dataa P, Alnemri ES, and Shi Y (2001) Structural basis of caspase-7 inhibition by XIAP. Cell 104: 769-780
DOI
ScienceOn
|
44 |
Chen Z, Naito M, Hori S, Mashima T, Yamori T, and Tsuruo T (1999) A human IAP-family gene, Apollon, expressed in human brain cancer cells. Biochem Biophys Res Commun 264: 847-854
DOI
ScienceOn
|
45 |
Altieri DC (2003) Survivin, versatile modulation of cell division and apoptosis in cancer. Oncogene 22: 8581-8589
DOI
ScienceOn
|
46 |
Ambrosini G, Adida C, and Altieri DC (1997) A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 3: 917-921
DOI
ScienceOn
|
47 |
Srinivasula SM, Datta P, Kobayashi M, Wu J-W, Fujioka M, Hedge R, Zhang Z, Makattash R, Fernandes-Alnemri T, Shi Y, Jaynes JB, and Alnemri ES (2002) Sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein. Curr Biol 12: 125-130
DOI
ScienceOn
|
48 |
Uren AG, Wong L, Pakusch M, Fowler KJ, Burrows FJ, Vaux DL, and Choo KH (2000) Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr Biol 10: 1319-1328
DOI
ScienceOn
|
49 |
Tenev T, Zachariou A, Wilson R, Paul A, and Meier P (2002) Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1. EMBO J 21: 6118-5129
DOI
ScienceOn
|
50 |
Uren AG, Coulson EJ, and Vaux DL (1998) Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts. Trends Biochem Sci 5: 159-162
DOI
ScienceOn
|
51 |
Ryoo HD, Gorenc T, and Steller H (2004) Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways. Dev Cell 7: 491-501
DOI
ScienceOn
|
52 |
Suzuki Y, Nakabayashi Y, and Takahashi R (2001) Ubiquitin protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proc Natl Acad Sci USA 98: 8662-8667
DOI
ScienceOn
|
53 |
Speliotes EK, Uren A, Vaux D, and Horvitz HR (2000) The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone. Mol Cell 6: 211-223
DOI
ScienceOn
|
54 |
Shin S, Sung BJ, Cho YS, Kim HJ, Ha NC, Hwang JL, Chung CW, Jung YK, and Oh BH (2001) An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7. Biochemistry 40: 1117-1123
DOI
ScienceOn
|
55 |
Silke J, Kratina T, Chu E, Ekert PG, Day CL, Pajusch M, Huang DCS, and Vaux DL (2005) Determination of cell survival by Ring-mediated regulation of inhibitor of apoptosis (IAP) protein abundance. Proc Natl Acad Sci USA 102: 16182-16187
DOI
ScienceOn
|
56 |
Sanna MG, da Silva Correia J, Ducrey O, Lee J, Nomoto K, Schrantz N, Deveraux QL, and Ulevitch RJ (2002) IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition. Mol Cell Biol 22: 1754-1766
DOI
|
57 |
Schimmer AD (2004) Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice. Cancer Res 64: 7183-7190
DOI
ScienceOn
|
58 |
Zimmermann KC, Ricci J-E, Droin NM, and Green DR (2002) The role of ARK in stress-induced apoptosis in Drosophila cells. J Cell Biol 156: 1077-1087
DOI
ScienceOn
|
59 |
Schwerk C and Schulze-Osthoff K (2003) Non-apoptotic functions of caspases in cellular proliferation and differentiation. Biochem Pharmacol 66: 1453-1458
DOI
ScienceOn
|
60 |
Ryoo HD, Bergmann A, Gonen H, Ciechanover A, and Steller H (2002) Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1. Nat Cell Biol 4: 432-438
DOI
ScienceOn
|
61 |
O'Connor DS, Grossman D, Li F, Zhang H, Villa A, Tognin S, Marchisio PC, and Altieri DC (2000) Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc Natl Acad Sci USA 97: 13107-13107
DOI
ScienceOn
|
62 |
Yoo SJ, Huh JR, Muro I, Yu H, Wang L, Wang SL, Feldman RM, Clem RJ, Muller HA, and Hay BA (2002) Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nat Cell Biol 4: 416-24
DOI
ScienceOn
|
63 |
Zhou R, Silverman N, Hong M, Liao DS, Chung Y, Chen ZJ, and Maniatis T (2005) The role of ubiquitination in Drosophila innate immunity. J Biol Chem 280: 34048-34055
DOI
ScienceOn
|
64 |
Samuel T, Okada K, Hyer M, Welsh K, Zapata JM, and Reed JC (2005a) cIAP1 localizes to the nuclear compartment and modulates the cell cycle. Cancer Res 65: 210-218
|
65 |
Samuel T, Welsh K, Lober T, Togo SH, Zapata JM, and Reed JC (2005b) Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of TRAF2 and Smac. J Biol Chem Nov doi: 10.1074/jbc.M509381200: in press
DOI
ScienceOn
|
66 |
Reed JC (2001) The survivin saga goes in vivo. J Clin Invest 108: 965-969
DOI
|
67 |
Yang Y, Fang S, Jensen JP, Wissman AM, and Ashwell JD (2000) Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. Science 288: 874-877
DOI
ScienceOn
|
68 |
Rothe M, Pan M-G, Henzel WJ, Ayres TM, and Goeddel DV (1995) The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83: 1243-1252
DOI
ScienceOn
|
69 |
Roy N, Mahadevan MS, Mclean M, Shutler G, Yaraghi Z, Farahani R, Baird S, Besnerjohnston A, Lefebvre C, and Kang XL (1995) The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 80: 167-178
DOI
ScienceOn
|
70 |
Marusawa H, Matsuzawa S-I, Welsh K, Zou H, Armstrong R, Tamm I, and Reed JC (2003) HBXIP functions as a cofactor of survivin in apoptosis suppression. EMBO J 22: 2729-2740
DOI
ScienceOn
|
71 |
Li X, Yang Y, and Ashwell JD (2002) TNF-RII and cIAP1 mediate ubiquitination and degradation of TRAF2. Nature 416: 345-347
DOI
ScienceOn
|
72 |
Yang QH, Church-Hajduk R, Ren J, Newton ML, and Du C (2003) Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis. Genes Dev 17: 1487-1496
DOI
ScienceOn
|
73 |
Olson MR, Holley CL, Gan EC, Colon-Ramos DA, Kaplan B, and Kornbluth S (2003) Reaper is regulated by IAP-mediated ubiquitination. J Biol Chem 278: 4028-4034
DOI
ScienceOn
|
74 |
Plenchette S, Cathelin S, Rebe C, Launay S, Ladoire S, Sordet O, Ponnelle T, Debili N, Phan T-H, Padua R-A, Dubrez-Daloz L, and Solary E (2004) Translocation of the inhibitor of apoptosis protein cIAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: a nuclear export signal-mediated event. Blood 104: 2035-2043
DOI
ScienceOn
|
75 |
Kuranaga E, Kanuka H, Igaki T, Sawamoto K, Ichijo H, Okano H, and Miura M (2002) Reaper-mediated inhibition of Diap 1-induced DTRAF degradation results in activation of JNK in Drosophila. Nat Cell Biol 4: 705-710
DOI
ScienceOn
|
76 |
Yamaguchi K, Nagai S, Ninomiya-Tsuji J, Nishita M, Tamai K, Irie K, Ueno N, Nishida E, Shibuya H, and Matsumoto K (1999) XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. EMBO J 18: 179-187
DOI
ScienceOn
|
77 |
Levkau B, Garton KJ, Ferri N, Kloke k, Nofer JR, Baba HA, Raines EW, and Breithardt G (2001) XIAP induces cell-cycle arrest and activates nuclear factor-kappaB: new survival pathways diabled by caspase-mediated cleavage during apoptosis of human endothelial cells. Circ Res 88: 282-290
DOI
ScienceOn
|
78 |
Lewis j, Burstein E, Reffey SB, Bratton SB, Roberts AB, and Duckett CS (2004) Uncoupling of the signaling and caspase-inhibitory properties of X-linked inhibitor of apoptosis. J Biol Chem 279: 9023-9029
DOI
ScienceOn
|
79 |
Li F, Ambrosini G, Chu EY, Marchisio PC, and Altieri DC (1998) Cell cycle control of apoptosis and mitotic spindle checkpoint by survivin. Nature 396: 580-584
DOI
ScienceOn
|
80 |
Li T, Ackermann EJ, Bennett CV, Rothermel AL, Plescia J, Tognin S, Villa A, Marchisio PC, and Altieri DC (1999) Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat Cell Biol 1: 461-466
DOI
|
81 |
Liston P, Fong WG, Kelly NL, Toji S, Miyazaki T, Conte D, Tamai K, Craig CG, McBurney MW, and Korneluk RG (2001) Identification of XAF1 as an antagonist of XIAP anticaspase activity. Nat Cell Biol 3: 128-133
DOI
ScienceOn
|
82 |
MacFarlane M, Merrison W, Bratton SB, and Cohen GM (2002) Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro. J Biol Chem 277: 36611-36616
DOI
ScienceOn
|
83 |
Holcik M, Sonenberg N, and Korneluk RG (2000) Internal ribosome initiation of translation and the control of cell death. Trends Genet 16: 469-473
DOI
ScienceOn
|