1 |
Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, Goldstein JL, and Brown MS (2002) Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 110: 489-500
DOI
ScienceOn
|
2 |
Wang X, Briggs MR, Hua X, Yokoyama C, Goldstein JL, and Brown MS (1993) Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization. J Biol Chem 268: 14497-14504
|
3 |
Wang X, Sato R, Brown MS, Hua X, and Goldstein JL (1994) SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 77: 53-62
DOI
ScienceOn
|
4 |
Yabe D, Brown MS, and Goldstein JL (2002) Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins. Proc Natl Acad Sci USA 99: 12753-12758
DOI
ScienceOn
|
5 |
Yabe D, Komuro R, Liang G, Goldstein JL, and Brown MS (2003) Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis. Proc Natl Acad Sci USA 100: 3155-3160
DOI
ScienceOn
|
6 |
Tontonoz P, Kim JB, Graves RA, and Spiegelman BM (1993) ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol Cell Biol 13: 4753-4759
DOI
|
7 |
Tuteja R and Tuteja N (2000) Ku autoantigen: a multifunctional DNA-binding protein. Crit Rev Biochem Mol Biol 35: 1-33
DOI
ScienceOn
|
8 |
Wang G, Caltin GT, Stevens JL, and Berk AJ (2001) Characterization of mediator complexes from Hela cell nuclear extract. Mol Cell Biol 21: 4604-4613
DOI
ScienceOn
|
9 |
Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, and Goldstein JL (1997a) Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest 99: 846-854
DOI
ScienceOn
|
10 |
Shimano H, Shimomura I, Hammer RE, Herz J, Goldstein JL, Brown MS, and Horton JD (1997b) Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. J Clin Invest 100: 2115-2124
DOI
ScienceOn
|
11 |
Shimomura I, Shimano H, Korn BS, Bashmakov Y, and Horton JD (1998a) Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biogenesis in transgenic mouse liver. J Biol Chem 273: 35299-35306
DOI
ScienceOn
|
12 |
Shimomura I, Hammer RE, Richardson JA, Ikemoto S, Bashmakov Y, Goldstein JL, and Brown MS (1998b) Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. Genes Dev 12: 3182-3194
DOI
ScienceOn
|
13 |
Rachez C, Lemon BD, Suldan Z, Bromleigh V, Gamble M, Naar AM, Erdjument-Bromage H, Tempst P, and Freedman LP (1999) Ligand-dependent activation by nuclear receptors requires the DRIP complex. Nature 398: 824-828
DOI
ScienceOn
|
14 |
Sanchez HB, Yieh L, and Osborne TF (1995) Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene. J Biol Chem 270: 1161-1169
DOI
ScienceOn
|
15 |
Sato R, Yang J, Wang X, Evans MJ, Ho YK, Goldstein JL, and Brown MS (1994) Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1). J Biol Chem 269: 17267-17273
|
16 |
Quinn JB and Farira AR (1991) Autoimmune antigen Ku is enriched on oligonucleotide columns distinct from those containing the octamer binding protein DNA consensus sequence. FEBS Lett 286: 225-228
DOI
ScienceOn
|
17 |
Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, and Brown MS (2002) Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J Biol Chem 277: 9520-9528
DOI
ScienceOn
|
18 |
Naar AM, Beaurang PA, Robinson KM, Oliner JD, Avizonis D, Scheek S, Zwicker J, Kadonaga JT, and Tjian R (1998) Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro. Genes Dev 12: 3020-3031
DOI
ScienceOn
|
19 |
Naar AM, Beaurang PA, Zhou S, Abraham S, Solomon W, and Tjian R (1999) Composite co-activator ARC mediates chromatin-directed transcriptional activation. Nature 398: 828-832
DOI
ScienceOn
|
20 |
Magana MM, Koo SH, Towle HC, and Osborne TF (2000) Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase. J Biol Chem 275: 4726-4733
DOI
ScienceOn
|
21 |
Lim JW, Kim H, and Kim KH (2004) The Ku antigen-recombination signal-binding protein J{ } complex binds to the nuclear factor-{ }B p50 promoter and acts as a positive regulator of p50 expression in human gastric cancer cells. J Biol Chem 279: 231-237
DOI
ScienceOn
|
22 |
Lopez JM, Bennette MK, Sanchez HB, Rosenfeld JM, and Osborne TE (1996) Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid. Proc Natl Acad Sci USA 93: 1049-1053
DOI
ScienceOn
|
23 |
Magana MM and Osborne TF (1996) Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter. J Biol Chem 271: 32689-32694
DOI
ScienceOn
|
24 |
Ito M, Yuan C, Okano HJ, Darnell RB, and Roeder RG (2000) Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. Mol Cell 5: 683-693
DOI
ScienceOn
|
25 |
Knuth MW, Gunderson SI, Thompson NE, Strasheim LA, and Burgess RR (1990) Purification and characterization of proximal sequence element-binding protein I, a transcription activating protein related to Ku and TREF that binds the proximal sequence element of the human U1 promoter. J Biol Chem 265: 17911-17920
|
26 |
Lee YS, Lee HH, Park J, Yoo EJ, Glackin CA, Choi YI, Jeon SH, Seong RH, Park SD, and Kim JB (2003) Twist2, a novel ADD1/SREBP1c interacting protein, represses the transcriptional activity of ADD1/SREBP1c. Nucleic Acids Res 31: 7165-7174
DOI
ScienceOn
|
27 |
Lees-Miller SP, Chen YR, and Anderson CW (1990) Human cells contain a DNA-activated protein kinase that phosphorylates Simian virus 40 T antigen, mouse p53, and the human Ku autoantigen. Mol Cell Biol 10: 6472-6481
DOI
|
28 |
Kim D, Ouyang H, Yang SH, Nussenzweig A, Burgman P, and Li GC (1995) A constitutive heat shock element-binding factor is immunologically identical to the Ku autoantigen. J Biol Chem 270: 15277-15284
DOI
ScienceOn
|
29 |
Kim JB and Spiegelman BM (1996) ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev 10: 1096-1107
DOI
ScienceOn
|
30 |
Kim JB, Wright HM, Wright M, and Spiegelman BM (1998a) ADD1/SREBP1 activates PPARg through the production of endogenous ligand. Proc Natl Acad Sci USA 95: 4333-4337
DOI
ScienceOn
|
31 |
Hua X, Nohturfft A, Goldstein JL, and Brown MS (1996) Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein. Cell 87: 415-426
DOI
ScienceOn
|
32 |
Kim JB, Sarraf P, Wright M, Yao KM, Mueller E, Solanes G, Lowell BB, and Spiegelman BM (1998b) Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J Clin Invest 101: 1-9
DOI
ScienceOn
|
33 |
Gottlieb TM and Jackson SP (1993) The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72: 131-142
DOI
ScienceOn
|
34 |
Horton JD, Goldstein JL, and Brown MS (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109: 1125-1131
DOI
|
35 |
Inoue J, Kumagai H, Terada T, Maeda M, Shimizu M, and Sato R (2001) Proteolytic activation of SREBPs during adipocyte differentiation. Biochem Biophys Res Commun 283: 1157-1161
DOI
ScienceOn
|
36 |
Dooley KA, Millinder S, and Osborne TF (1998) Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase gene through a direct interaction between sterol regulatory element binding protein and the trimeric CCAAT-binding factor/nuclear factor Y. J Biol Chem 273: 1349-1356
DOI
ScienceOn
|
37 |
Dvir A, Peterson SR, Kunth MW, Lu H, and Dyan WS (1992) Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II. Proc Natl Acad Sci USA 89: 11920-11924
DOI
ScienceOn
|
38 |
Falzon M, Fewell JW, and Kuff EL (1993) EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single to double-strand transitions in DNA. J Biol Chem 268: 10546-10552
|
39 |
Giffin W, Torrance H, Rodda DJ, Prefontaine GG, Pope L, and Hache RJG (1996) Sequence-specific DNA binding by Ku autoantigen and its effects on transcription. Nature 380: 265-268
DOI
ScienceOn
|
40 |
Falzon M and Kuff EL (1989) Isolation and characterization of a protein fracion that binds to enhancer core sequences in intracisternal A particle long terminal repeats. J Biol Chem 264: 21915-21922
|
41 |
Dignam JD, Martin PL, Shastry BS, and Roeder RG (1983a) Eukaryotic gene transcription with purified components. Methods Enzymol 101: 582-598
DOI
|
42 |
Dignam JD, Lebovitz RM, and Roeder RG (1983b) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acid Res 11: 1475-1489
DOI
ScienceOn
|
43 |
Brown MS and Goldstein JL (1999) A proteolytic pathway that controls the cholesterol content of membranes, cells and blood. Proc Natl Acad Sci USA 96: 11041-11048
DOI
|
44 |
deVries E, Driel WV, Bergsma WG, Arnberg AC, and van der Vliet PC (1989) Hela nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA forming a regular DNA multimeric protein complex. J Mol Biol 208: 65-78
DOI
|
45 |
Bene H, Lasky D, and Ntambi JM (2001) Cloning and characterization of the human stearyl-CoA desaturase gene promoter: transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol. Biochem Biophys Res Commun 284: 1194-1198
DOI
ScienceOn
|
46 |
Briggs MR, Yokoyama C, Wang X, Brown MS, and Goldstein JL (1993) Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence. J Biol Chem 268: 14490-14496
|