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The Olfactory Organ is Activated by a Repelling Pheromone in the Red-spotted Newt Notophthalmus viridescens  

Park, Daesik (Department of Biological Science, Northern Arizona University)
Propper, Catherine R. (Department of Biological Science, Northern Arizona University)
Publication Information
Animal cells and systems / v.6, no.3, 2002 , pp. 233-237 More about this Journal
Abstract
The pheromonal repelling response occurs when a combination of female and male pheromones is found to be less attractive to courting males than are female pheromones alone. This repelling response may act to conserve a courting males’reproductive fitness by minimizing ma1e-male competition within a courting group. Recently, a Pheromonal repelling response was first reported for vertebrates in the red-spotted newt, Notophthalmus viride-scens. A male cloacal pheromone, a ∼33 kDa protein, was identified as a repelling pheromone. In this study, to determine whether both the main olfactory epithelium (MOE) and/or the vomeronasal organ (VNO) are activated by the repelling pheromone, we recorded electrical field potentials from both olfactory epithelia while applying the repelling pheromone. The repelling pheromone induced electrical responses from both olfactory organs, and the magnitude of the response was greater in the VNO than in the MOE. Our results suggest that both the VNO and MOE may be involved in the pheromonal repelling response.
Keywords
Pheromone; Red-spotted newt; Vomeronasal organ; Main olfactory epithelium; Electro-olfactogram; Electro-vomeronasogram;
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Times Cited By KSCI : 1  (Citation Analysis)
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1 Leinders-Zufall T, Lane AP, Puche AC, Ma W, Novotny MV, Shipley MT and Zufall F (2000) Ultrasensitive pheromone detection by mammalian vomeronasal neurons, Nature 405: 792-796   DOI   ScienceOn
2 Park DS (2001) Amphibian Pheromonal Systems and Their Application for the Toxicological Study of Environmental Chemicals, Ph.D. Dissertation, Northern Arizona University, Flagstaff
3 Park DS, Hempleman S C and Propper CR (2001) Endosulfan exposure disrupts pheromonal systems in the red-spotted newt: a mechanism for subtle effects of environmental chemicals, Environ Health Perspect 109: 669-673   DOI
4 Sokal RR and Rohlf FJ (1981) Biometry, W. H. Freeman and Company, New York
5 Cohen-Tannoudji J, Lavenet C, Locatelli A, Tillet Y and Signoret J P (1989) Non-involvement of the accessory olfactory system in the LH response of anoestrous ewes to male odor, J Reprod Fertil 86: 135-144   DOI   ScienceOn
6 Vickers NJ, Christensen TA and Hildebrand JG (1998b) Combinatorial odor discrimination in the brain: attractive and antagonist odor blends are represented in distinct combinations of uniquely identifiable glomeruli, J Comp Neurol 400: 35-56   DOI   ScienceOn
7 Aujard F (1997) Effect of vomeronasal organ removal on male socio-sexual responses to female in a prosimian primate (Microcebus murinus), Physiol Behav 62: 1003-1008   DOI   ScienceOn
8 Beauchamp GK, Martin IG, Wysocki CJ and Wellington JL (1982) Chemoinvestgatory and sexual behavior of male guinea pigs following vomeronasal organ removal, Physiol Behav 29: 329-336   DOI   ScienceOn
9 Clutton-Brock TH and Vincent ACJ (1991) Sexual selection and the potential reproductive rates of males and females, Nature 351: 58-60   DOI   ScienceOn
10 Bijpost SCA, Thomas G and Krujit JP (1985) Olfactory interactions between sexually active males in Adoxophyes orana (F.V.R.) (Lepidoptera: Tortricidae), Behaviour 92: 121-137
11 Halpern M (1987) The organization and function of the vomeronasal system, Annu Rev Neurosci 10: 325-362   DOI   ScienceOn
12 Dorries KM, Adkins-Regan E and Halpern BP (1997) Sensitivity and behavioral responses to the pheromone androstenone are not mediated by the vomeronasal organ in domestic pigs, Brain Behav Evol 49: 53-62   DOI   ScienceOn
13 Dulac C (2000) Sensory coding of pheromone signals in mammals, Curr Opin Neurobiol 10: 511-518   DOI   ScienceOn
14 Johnson RE, Mller-Schwarze D and Sorensen PW (1999) Advances in Chemical Signals in Vertebrates, Kluwer Academic-Plenum Pulishers, New York
15 Lecomte C, Thibout E, Pierre D and Auger J (1998) Transfer, perception, and activity of male pheromon of Acroleptiopsis assectell a with special reference to conspecific male sexual inhibition, J Chem Ecol 24: 655-671   DOI   ScienceOn
16 Pool TB and Dent JN (1977) Neural regulation of product discharge from the hedonic glands of the red-spotted newt, Notophthalmus viridescens, J Exp Zool 201: 203-220   DOI
17 Swann J, Rahaman F, Bijak T and Fiber J (2001) The main olfactory system mediates pheromone-induced for expression in the extended amygdala and preoptic area of the male Syrian hamster, Neuroscience 105: 695-706   DOI   ScienceOn
18 Toyoda F, Kiuyama S, Hayakawa Y, Ichikawa M and Kikuyam S (1999) Olfactory response to a female-attracting pheromonein the newt, Cynops pyrrhogaster In: Johnston RE, Mller-Schwarz D and Sorensen PW (eds), Advances in Chemical Signals in Vertebrates, Kluwer Academic/Plenum Publishers, New York, pp. 55-615
19 Curtis JT, Liu Y and Wang Z (2001) Lesions of the vomeronasal organ disrupt mating-induced pair bonding in female prairie voles (Mcrotus ochrogaster), Brain Res 901: 167-174   DOI   ScienceOn
20 Dawely EM and Bass AH (1989) Chemical access to the vomeronasal organs of aplethodontid salamander, J Morphol 200: 163-174   DOI
21 Johnson RE (2000) Chemical communication and pheromones: the types of chmical signals and the role of the vomero nasal system In: Finger TE, Silver WL and Restre D (eds), The Neurobiology of Taste and Smell, John Wiley and Sons, Inc., New York, pp. 101-127
22 Vickers NJ, Christensen TA and Hildebrand JG (1998a) Intergrating behavior with neurobiology: odor-mediated moth flight and olfactory discrimination by glomerular arrays, Integr Biol 1: 224-230   DOI   ScienceOn
23 Keverne EB (1999) The vomeronasal organ, Science 286: 716-720   DOI   ScienceOn
24 Park DS and Propper CR (2001) Repellent fuction of male pheromone in the red-spotted newt, J Exp Zool 289: 404-408   DOI   ScienceOn
25 Kikuyama S, Toyoda F, Ohmiya Y, Matuda K, Tanaka S and Hayashi H (1995) Soderfrin: a female-attracting peptide pheromone in newt cloacal glands, Science 267: 1643-1645   DOI   ScienceOn
26 Rollmann SM, Houck LD and Feldhoff RC (1999) Proteinaceous pheromone affecting female receptivity in a terrestrial salamander, Science 285: 1907-1909   DOI   ScienceOn
27 Sam M, Vora S, Malnic D, Ma W, Novotny MV and Buck LB (2001) Neuropharmacology: Odorants may arouse instinctive behaviours, Nature 412: 142   DOI   ScienceOn
28 Toyoda F and Kikuyama S (2000) Hormonal influence on the olfactory response to female-attracting pheromone, Sodefrin, in the newt, Cynops pyrrhogaster, Comp Biochem Physiol B 126: 239-245   DOI   ScienceOn
29 Verrell P (1982) The sexual behavior of the red-spotted newt, Notophthalmus viridescens (Amphibia: Urodela: Salamandridae), Anim Behav 30: 1224-1236   DOI