Browse > Article
http://dx.doi.org/10.14348/molcells.2021.0263

No Time to Die, Born to Be Killers: Survival Is Accompanied by Exhaustion after an Endless Battle  

Diederich, Sarah (BK21 Four Program, College of Pharmacy, Seoul National University)
Chung, Yeonseok (BK21 Four Program, College of Pharmacy, Seoul National University)
Keywords
Citations & Related Records
연도 인용수 순위
  • Reference
1 Abdel-Hakeem, M.S., Manne, S., Beltra, J.C., Stelekati, E., Chen, Z., Nzingha, K., Ali, M.A., Johnson, J.L., Giles, J.R., Mathew, D., et al. (2021). Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation. Nat. Immunol. 22, 1008-1019.   DOI
2 Khan, O., Giles, J.R., McDonald, S., Manne, S., Ngiow, S.F., Patel, K.P., Werner, M.T., Huang, A.C., Alexander, K.A., Wu, J.E., et al. (2019). TOX transcriptionally and epigenetically programs CD8(+) T cell exhaustion. Nature 571, 211-218.   DOI
3 Alfei, F., Kanev, K., Hofmann, M., Wu, M., Ghoneim, H.E., Roelli, P., Utzschneider, D.T., von Hoesslin, M., Cullen, J.G., Fan, Y., et al. (2019). TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection. Nature 571, 265-269.   DOI
4 Beltra, J.C., Manne, S., Abdel-Hakeem, M.S., Kurachi, M., Giles, J.R., Chen, Z., Casella, V., Ngiow, S.F., Khan, O., Huang, Y.J., et al. (2020). Developmental relationships of four exhausted CD8(+) T cell subsets reveals underlying transcriptional and epigenetic landscape control mechanisms. Immunity 52, 825-841.e8.   DOI
5 Yao, C., Sun, H.W., Lacey, N.E., Ji, Y., Moseman, E.A., Shih, H.Y., Heuston, E.F., Kirby, M., Anderson, S., Cheng, J., et al. (2019). Single-cell RNA-seq reveals TOX as a key regulator of CD8(+) T cell persistence in chronic infection. Nat. Immunol. 20, 890-901.   DOI
6 Kim, B.S., Kuen, D.S., Koh, C.H., Kim, H.D., Chang, S.H., Kim, S., Jeon, Y.K., Park, Y.J., Choi, G., Kim, J., et al. (2021). Type 17 immunity promotes the exhaustion of CD8(+) T cells in cancer. J. Immunother. Cancer 9, e002603.   DOI