1 |
Janssens, S., Schotsaert, M., Karnik, R., Balasubramaniam, V., Dejosez, M., Meissner, A., García-Sastre, A., and Zwaka, T.P. (2018). Zika virus alters DNA methylation of neural genes in an organoid model of the developing human brain. mSystems 3, e00219-e00217.
|
2 |
Jo, J., Xiao, Y., Sun, A.X., Cukuroglu, E., Tran, H.D., Göke, J., Tan, Z.Y., Saw, T.Y., Tan, C.P., Lokman, H., et al. (2016). Midbrain-like organoids from human pluripotent stem cells contain functional dopaminergic and neuromelanin-producing neurons. Cell Stem Cell 19, 248-257.
DOI
|
3 |
Karzbrun, E., Kshirsagar, A., Cohen, S.R., Hanna, J.H., and Reiner, O. (2018). Human brain organoids on a chip reveal the physics of folding. Nat. Phys. 14, 515-522.
DOI
|
4 |
Karzbrun, E., Reiner, O., Karzbrun, E., and Reiner, O. (2019). Brain organoids-a bottom-up approach for studying human neurodevelopment. Bioengineering (Basel) 6, E9.
DOI
|
5 |
Kim, H., Park, H.J., Choi, H., Chang, Y., Park, H., Shin, J., Kim, J., Lengner, C.J., Lee, Y.K., and Kim, J. (2019a). Modeling G2019S-LRRK2 sporadic Parkinson's disease in 3D midbrain organoids. Stem Cell Reports 12, 518-531.
DOI
|
6 |
Kim, J., Koo, B.K., and Yoon, K.J. (2019b). Modeling host-virus interactions in viral infectious diseases using stem-cell-derived systems and CRISPR/Cas9 technology. Viruses 11, E124.
DOI
|
7 |
Thomson, J.A., Itskovitz-Eldor, J., Shapiro, S.S., Waknitz, M.A., Swiergiel, J.J., Marshall, V.S., and Jones, J.M. (1998). Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147.
DOI
|
8 |
Trujillo, C.A., Gao, R., Negraes, P.D., Gu, J., Buchanan, J., Preissl, S., Wang, A., Wu, W., Haddad, G.G., Chaim, I.A., et al. (2019). Complex oscillatory waves emerging from cortical organoids model early human brain network development. Cell Stem Cell 25, 1-12.
DOI
|
9 |
Tung, T.C. and Kü, S.H. (1944). Experimental studies on the development of the pronephric duct in anuran embryos. J. Anat. 78, 52-57.
|
10 |
Valiente, M. and Marin, O. (2010). Neuronal migration mechanisms in development and disease. Curr. Opin. Neurobiol. 20, 68-78.
DOI
|
11 |
Shi, Y., Kirwan, P., Smith, J., Robinson, H.P.C., and Livesey, F.J. (2012). Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat. Neurosci. 15, 477-486, S1.
DOI
|
12 |
Li, Y., Muffat, J., Omer, A., Bosch, I., Lancaster, M.A., Sur, M., Gehrke, L., Knoblich, J.A., and Jaenisch, R. (2017). Induction of expansion and folding in human cerebral organoids. Cell Stem Cell 20, 385-396.e3.
DOI
|
13 |
Kopper, O., de Witte, C.J., Lohmussaar, K., Valle-Inclan, J.E., Hami, N., Kester, L., Balgobind, A.V., Korving, J., Proost, N., Begthel, H., et al. (2019). An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity. Nat. Med. 25, 838-849.
DOI
|
14 |
van de Wetering, M., Francies, H.E., Francis, J.M., Bounova, G., Iorio, F., Pronk, A., van Houdt, W., van Gorp, J., Taylor-Weiner, A., Kester, L., et al. (2015). Prospective derivation of a living organoid biobank of colorectal cancer patients. Cell 161, 933-945.
DOI
|
15 |
Velasco, S., Kedaigle, A.J., Simmons, S.K., Nash, A., Rocha, M., Quadrato, G., Paulsen, B., Nguyen, L., Adiconis, X., Regev, A., et al. (2019). Individual brain organoids reproducibly form cell diversity of the human cerebral cortex. Nature 570, 523-527.
DOI
|
16 |
Kriegstein, A.R. and Noctor, S.C. (2004). Patterns of neuronal migration in the embryonic cortex. Trends Neurosci. 27, 392-399.
DOI
|
17 |
Lancaster, M.A. and Knoblich, J.A. (2014). Organogenesis in a dish: modeling development and disease using organoid technologies. Science 345, 1247125.
DOI
|
18 |
Lancaster, M.A., Renner, M., Martin, C.A., Wenzel, D., Bicknell, L.S., Hurles, M.E., Homfray, T., Penninger, J.M., Jackson, A.P., and Knoblich, J.A. (2013). Cerebral organoids model human brain development and microcephaly. Nature 501, 373-379.
DOI
|
19 |
Levitt, P. and Veenstra-VanderWeele, J. (2015). Neurodevelopment and the origins of brain disorders. Neuropsychopharmacology 40, 1-3.
DOI
|
20 |
Lin, Y.T., Seo, J., Gao, F., Feldman, H.M., Wen, H.L., Penney, J., Cam, H.P., Gjoneska, E., Raja, W.K., Cheng, J., et al. (2018). APOE4 causes widespread molecular and cellular alterations associated with Alzheimer's disease phenotypes in human iPSC-derived brain cell types. Neuron 98, 1141-1154.e7.
DOI
|
21 |
Linkous, A., Balamatsias, D., Snuderl, M., Pisapia, D., Liston, C., and Correspondence, H.A.F. (2019). Modeling patient-derived glioblastoma with cerebral organoids. Cell Rep. 26, 3203-3211.e5.
DOI
|
22 |
Lui, J.H., Hansen, D.V., and Kriegstein, A.R. (2011). Development and evolution of the human neocortex. Cell 146, 18-36.
DOI
|
23 |
Werner, S., Vu, H.T., and Rink, J.C. (2017). Self-organization in development, regeneration and organoids. Curr. Opin. Cell Biol. 44, 102-109.
DOI
|
24 |
Vijayavenkataraman, S., Yan, W.C., Lu, W.F., Wang, C.H., and Fuh, J.Y.H. (2018). 3D bioprinting of tissues and organs for regenerative medicine. Adv. Drug Deliv. Rev. 132, 296-332.
DOI
|
25 |
Wang, P., Mokhtari, R., Pedrosa, E., Kirschenbaum, M., Bayrak, C., Zheng, D., and Lachman, H.M. (2017). CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells. Mol. Autism 8, 11.
DOI
|
26 |
Watanabe, M., Buth, J.E., Vishlaghi, N., de la Torre-Ubieta, L., Taxidis, J., Khakh, B.S., Coppola, G., Pearson, C.A., Yamauchi, K., Gong, D., et al. (2017). Self-organized cerebral organoids with human-specific features predict effective drugs to combat Zika virus infection. Cell Rep. 21, 517-532.
DOI
|
27 |
Wilson, H.V. (1907). On some phenomena of coalescence and regeneration in sponges. J. Exp. Zool. 5, 245-258.
DOI
|
28 |
Wimmer, R.A., Leopoldi, A., Aichinger, M., Wick, N., Hantusch, B., Novatchkova, M., Taubenschmid, J., Hammerle, M., Esk, C., Bagley, J.A., et al. (2019). Human blood vessel organoids as a model of diabetic vasculopathy. Nature 565, 505-510.
DOI
|
29 |
Madhavan, M., Nevin, Z.S., Shick, H.E., Garrison, E., Clarkson-Paredes, C., Karl, M., Clayton, B.L.L., Factor, D.C., Allan, K.C., and Barbar, L. (2018). Induction of myelinating oligodendrocytes in human cortical spheroids. Nat. Methods 15, 700-706.
DOI
|
30 |
Xia, Y., Sancho-Martinez, I., Nivet, E., Rodriguez Esteban, C., Campistol, J.M., and Izpisua Belmonte, J.C. (2014). The generation of kidney organoids by differentiation of human pluripotent cells to ureteric bud progenitor-like cells. Nat. Protoc. 9, 2693-2704.
DOI
|
31 |
Mansour, A.A., Gonçalves, J.T., Bloyd, C.W., Li, H., Fernandes, S., Quang, D., Johnston, S., Parylak, S.L., Jin, X., and Gage, F.H. (2018). An in vivo model of functional and vascularized human brain organoids. Nat. Biotechnol. 36, 432-441.
DOI
|
32 |
Mariani, J., Coppola, G., Zhang, P., Abyzov, A., Provini, L., Tomasini, L., Amenduni, M., Szekely, A., Palejev, D., Wilson, M., et al. (2015). FOXG1-dependent dysregulation of GABA/Glutamate neuron differentiation in autism spectrum disorders. Cell 162, 375-390.
DOI
|
33 |
Martin, G.R. (1981). Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. U. S. A. 78, 7634-7638.
DOI
|
34 |
Marton, R.M., Miura, Y., Sloan, S.A., Li, Q., Revah, O., Levy, R.J., Huguenard, J.R., and Pasca, S.P. (2019). Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures. Nat. Neurosci. 22, 484-491.
DOI
|
35 |
Mitchell, K.J. (2011). The genetics of neurodevelopmental disease. Curr. Opin. Neurobiol. 21, 197-203.
DOI
|
36 |
Mlakar, J., Korva, M., Tul, N., Popović, M., Poljsak-Prijatelj, M., Mraz, J., Kolenc, M., Resman Rus, K., Vesnaver Vipotnik, T., Fabjan Vodusek, V., et al. (2016). Zika virus associated with microcephaly. N. Engl. J. Med. 374, 951-958.
DOI
|
37 |
Muguruma, K., Nishiyama, A., Kawakami, H., Hashimoto, K., and Sasai, Y. (2015). Self-organization of polarized cerebellar tissue in 3D culture of human pluripotent stem cells. Cell Rep. 10, 537-550.
DOI
|
38 |
Yan, H.H.N., Siu, H.C., Law, S., Ho, S.L., Yue, S.S.K., Tsui, W.Y., Chan, D., Chan, A.S., Ma, S., Lam, K.O., et al. (2018). A comprehensive human gastric cancer organoid biobank captures tumor subtype heterogeneity and enables therapeutic screening. Cell Stem Cell 23, 882-897.e11.
DOI
|
39 |
Xu, M., Lee, E.M., Wen, Z., Cheng, Y., Huang, W.K., Qian, X., Tcw, J., Kouznetsova, J., Ogden, S.C., Hammack, C., et al. (2016). Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen. Nat. Med. 22, 1101-1107.
DOI
|
40 |
Yamanaka, S. (2012). Induced pluripotent stem cells: past, present, and future. Cell Stem Cell 10, 678-684.
DOI
|
41 |
Yin, X., Mead, B.E., Safaee, H., Langer, R., Karp, J.M., and Levy, O. (2016). Engineering stem cell organoids. Cell Stem Cell 18, 25-38.
DOI
|
42 |
Yoon, K.J., Nguyen, H.N., Ursini, G., Zhang, F., Kim, N.S., Wen, Z., Makri, G., Nauen, D., Shin, J.H., Park, Y., et al. (2014). Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity. Cell Stem Cell 15, 79-91.
DOI
|
43 |
Yoon, K.J., Ringeling, F.R., Vissers, C., Jacob, F., Pokrass, M., Jimenez-Cyrus, D., Su, Y., Kim, N.S., Zhu, Y., Zheng, L., et al. (2017a). Temporal control of mammalian cortical neurogenesis by m(6)A methylation. Cell 171, 877-889.e17.
DOI
|
44 |
Yoon, K.J., Song, G., Qian, X., Pan, J., Xu, D., Rho, H.S., Kim, N.S., Habela, C., Zheng, L., Jacob, F., et al. (2017b). Zika-virus-encoded NS2A disrupts mammalian cortical neurogenesis by degrading adherens junction proteins. Cell Stem Cell 21, 349-358.e6.
DOI
|
45 |
Charras, G. and Yap, A.S. (2018). Tensile forces and mechanotransduction at cell-cell junctions. Curr. Biol. 28, R445-R457.
DOI
|
46 |
Murphy, S.V. and Atala, A. (2014). 3D bioprinting of tissues and organs. Nat. Biotechnol. 32, 773-785.
DOI
|
47 |
Bian, S., Repic, M., Guo, Z., Kavirayani, A., Burkard, T., Bagley, J.A., Krauditsch, C., and Knoblich, J.A. (2018). Genetically engineered cerebral organoids model brain tumor formation. Nat. Methods 15, 631-639.
DOI
|
48 |
Birey, F., Andersen, J., Makinson, C.D., Islam, S., Wei, W., Huber, N., Fan, H.C., Metzler, K.R.C., Panagiotakos, G., Thom, N., et al. (2017). Assembly of functionally integrated human forebrain spheroids. Nature 545, 54-59.
DOI
|
49 |
Buchanan, M. (2018). Organoids of intelligence. Nat. Phys. 14, 634.
DOI
|
50 |
Camp, J.G., Badsha, F., Florio, M., Kanton, S., Gerber, T., Wilsch-Brauninger, M., Lewitus, E., Sykes, A., Hevers, W., Lancaster, M., et al. (2015). Human cerebral organoids recapitulate gene expression programs of fetal neocortex development. Proc. Natl. Acad. Sci. U. S. A. 112, 15672-15677.
DOI
|
51 |
Choi, Y.H. and Kim, J.K. (2019). Dissecting cellular heterogeneity using single-cell RNA sequencing. Mol. Cells 42, 189-199.
DOI
|
52 |
Cugola, F.R., Fernandes, I.R., Russo, F.B., Freitas, B.C., Dias, J.L.M., Guimarães, K.P., Benazzato, C., Almeida, N., Pignatari, G.C., Romero, S., et al. (2016). The Brazilian Zika virus strain causes birth defects in experimental models. Nature 534, 267-271.
DOI
|
53 |
Park, S.E., Georgescu, A., and Huh, D. (2019). Organoids-on-a-chip. Science 364, 960-965.
DOI
|
54 |
Ogawa, J., Pao, G.M., Shokhirev, M.N., and Verma, I.M. (2018). Glioblastoma model using human cerebral organoids. Cell Rep. 23, 1220-1229.
DOI
|
55 |
Oh, Y. and Jang, J. (2019). Directed differentiation of pluripotent stem cells by transcription factors. Mol. Cells 42, 200-209.
DOI
|
56 |
Ormel, P.R., Vieira de Sa, R., van Bodegraven, E.J., Karst, H., Harschnitz, O., Sneeboer, M.A.M., Johansen, L.E., van Dijk, R.E., Scheefhals, N., Berdenis van Berlekom, A., et al. (2018). Microglia innately develop within cerebral organoids. Nat. Commun. 9, 4167.
DOI
|
57 |
Pasca, A.M., Park, J.Y., Shin, H.W., Qi, Q., Revah, O., Krasnoff, R., O'Hara, R., Willsey, A.J., Palmer, T.D., and Pasca, S.P. (2019). Human 3D cellular model of hypoxic brain injury of prematurity. Nat. Med. 25, 784-791.
DOI
|
58 |
Pasca, A.M., Sloan, S.A., Clarke, L.E., Tian, Y., Makinson, C.D., Huber, N., Kim, C.H., Park, J.Y., O'Rourke, N.A., Nguyen, K.D., et al. (2015). Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Nat. Methods 12, 671-678.
DOI
|
59 |
Plummer, S., Wallace, S., Ball, G., Lloyd, R., Schiapparelli, P., Quinones-Hinojosa, A., Hartung, T., and Pamies, D. (2019). A human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine. Sci. Rep. 9, 1407.
DOI
|
60 |
Qian, X., Jacob, F., Song, M.M., Nguyen, H.N., Song, H., and Ming, G.l. (2018). Generation of human brain region-specific organoids using a miniaturized spinning bioreactor. Nat. Protoc. 13, 565-580.
DOI
|
61 |
Zhang, S.C., Wernig, M., Duncan, I.D., Brustle, O., and Thomson, J.A. (2001). In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat. Biotechnol. 19, 1129-1133.
DOI
|
62 |
Yoon, S.J., Elahi, L.S., Pasca, A.M., Marton, R.M., Gordon, A., Revah, O., Miura, Y., Walczak, E.M., Holdgate, G.M., Fan, H.C., et al. (2019). Reliability of human cortical organoid generation. Nat. Methods 16, 75-78.
DOI
|
63 |
Yu, J., Vodyanik, M.A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J.L., Tian, S., Nie, J., Jonsdottir, G.A., Ruotti, V., Stewart, R., et al. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920.
DOI
|
64 |
Yuan, L., Huang, X.Y., Liu, Z.Y., Zhang, F., Zhu, X.L., Yu, J.Y., Ji, X., Xu, Y.P., Li, G., Li, C., et al. (2017). A single mutation in the prM protein of Zika virus contributes to fetal microcephaly. Science 358, 933-936.
DOI
|
65 |
Zhong, X., Gutierrez, C., Xue, T., Hampton, C., Vergara, M.N., Cao, L.H., Peters, A., Park, T.S., Zambidis, E.T., Meyer, J.S., et al. (2014). Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs. Nat. Commun. 5, 4047.
DOI
|
66 |
Zhou, T., Tan, L., Cederquist, G.Y., Fan, Y., Hartley, B.J., Mukherjee, S., Tomishima, M., Brennand, K.J., Zhang, Q., Schwartz, R.E., et al. (2017). Highcontent screening in hPSC-neural progenitors identifies drug candidates that inhibit Zika virus infection in fetal-like organoids and adult brain. Cell Stem Cell 21, 274-283.e5.
DOI
|
67 |
Qian, X., Nguyen, H.N., Song, M.M., Hadiono, C., Ogden, S.C., Hammack, C., Yao, B., Hamersky, G.R., Jacob, F., Zhong, C., et al. (2016). Brain-regionspecific organoids using mini-bioreactors for modeling ZIKV exposure. Cell 165, 1238-1254.
DOI
|
68 |
Czerniecki, S.M., Cruz, N.M., Harder, J.L., Menon, R., Annis, J., Otto, E.A., Gulieva, R.E., Islas, L.V., Kim, Y.K., Tran, L.M., et al. (2018). Highthroughput screening enhances kidney organoid differentiation from human pluripotent stem cells and enables automated multidimensional phenotyping. Cell Stem Cell 22, 929-940.e4.
DOI
|
69 |
Dang, J., Tiwari, S.K., Lichinchi, G., Qin, Y., Patil, V.S., Eroshkin, A.M., and Rana, T.M. (2016). Zika virus depletes neural progenitors in human cerebral organoids through activation of the innate immune receptor TLR3. Cell Stem Cell 19, 258-265.
DOI
|
70 |
Dawson, T.M., Ko, H.S., and Dawson, V.L. (2010). Genetic animal models of Parkinson's disease. Neuron 66, 646-661.
DOI
|
71 |
Raja, W.K., Mungenast, A.E., Lin, Y.T., Ko, T., Abdurrob, F., Seo, J., and Tsai, L.H. (2016). Self-organizing 3D human neural tissue derived from induced pluripotent stem cells recapitulate Alzheimer's disease phenotypes. PLoS One 11, 1-18.
|
72 |
Zwilling, E. (1960). Some aspects of differentiation: disaggregation and reaggregation of early chick embryos. Natl. Cancer Inst. Monogr. 2, 19-39.
|
73 |
Eiraku, M., Takata, N., Ishibashi, H., Kawada, M., Sakakura, E., Okuda, S., Sekiguchi, K., Adachi, T., and Sasai, Y. (2011). Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 472, 51-56.
DOI
|
74 |
Eiraku, M., Watanabe, K., Matsuo-Takasaki, M., Kawada, M., Yonemura, S., Matsumura, M., Wataya, T., Nishiyama, A., Muguruma, K., and Sasai, Y. (2008). Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell 3, 519-532.
DOI
|
75 |
Gabriel, E., Ramani, A., Karow, U., Gottardo, M., Natarajan, K., Gooi, L.M., Goranci-Buzhala, G., Krut, O., Peters, F., Nikolic, M., et al. (2017). Recent Zika virus isolates induce premature differentiation of neural progenitors in human brain organoids. Cell Stem Cell 20, 397-406.e5.
DOI
|
76 |
Garcez, P.P., Loiola, E.C., Madeiro da Costa, R., Higa, L.M., Trindade, P., Delvecchio, R., Nascimento, J.M., Brindeiro, R., Tanuri, A., and Rehen, S.K. (2016). Zika virus impairs growth in human neurospheres and brain organoids. Science 352, 816-818.
DOI
|
77 |
Qian, X., Song, H., and Ming, G.L. (2019). Brain organoids: advances, applications and challenges. Development 146, dev166074.
|
78 |
Quadrato, G., Nguyen, T., Macosko, E.Z., Sherwood, J.L., Min Yang, S., Berger, D.R., Maria, N., Scholvin, J., Goldman, M., Kinney, J.P., et al. (2017). Cell diversity and network dynamics in photosensitive human brain organoids. Nature 545, 48-53.
DOI
|
79 |
Raslan, A.A. and Kee, Y. (2013). Tackling neurodegenerative diseases: animal models of Alzheimer's disease and Parkinson's disease. Genes Genom. 35, 425-440.
DOI
|
80 |
Sachs, N., de Ligt, J., Kopper, O., Gogola, E., Bounova, G., Weeber, F., Balgobind, A.V., Wind, K., Gracanin, A., Begthel, H., et al. (2018). A living biobank of breast cancer organoids captures disease heterogeneity. Cell 172, 373-386.e10.
DOI
|
81 |
Schafer, S.T., Paquola, A.C.M., Stern, S., Gosselin, D., Ku, M., Pena, M., Kuret, T.J.M., Liyanage, M., Mansour, A.A., Jaeger, B.N., et al. (2019). Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons. Nat. Neurosci. 22, 243-255.
DOI
|
82 |
Calvet, G., Aguiar, R.S., Melo, A.S.O., Sampaio, S.A., de Filippis, I., Fabri, A., Araujo, E.S.M., de Sequeira, P.C., de Mendonça, M.C.L., de Oliveira, L., et al. (2016). Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study. Lancet Infect. Dis. 16, 653-660.
DOI
|
83 |
Gaspard, N., Bouschet, T., Hourez, R., Dimidschstein, J., Naeije, G., Van den Ameele, J., Espuny-Camacho, I., Herpoel, A., Passante, L., and Schiffmann, S.N. (2008). An intrinsic mechanism of corticogenesis from embryonic stem cells. Nature 455, 351-357.
DOI
|
84 |
Grebenyuk, S. and Ranga, A. (2019). Engineering organoid vascularization. Front. Bioeng. Biotechnol. 7, 39.
DOI
|
85 |
Heymann, D.L., Hodgson, A., Sall, A.A., Freedman, D.O., Staples, J.E., Althabe, F., Baruah, K., Mahmud, G., Kandun, N., Vasconcelos, P.F., et al. (2016). Zika virus and microcephaly: why is this situation a PHEIC? Lancet 387, 719-721.
DOI
|
86 |
Hockemeyer, D. and Jaenisch, R. (2016). Induced pluripotent stem cells meet genome editing. Cell Stem Cell 18, 573-586.
DOI
|
87 |
Sakaguchi, H., Kadoshima, T., Soen, M., Narii, N., Ishida, Y., Ohgushi, M., Takahashi, J., Eiraku, M., and Sasai, Y. (2015). Generation of functional hippocampal neurons from self-organizing human embryonic stem cellderived dorsomedial telencephalic tissue. Nat. Commun. 6, 8896.
DOI
|
88 |
Sato, T., Vries, R.G., Snippert, H.J., van de Wetering, M., Barker, N., Stange, D.E., van Es, J.H., Abo, A., Kujala, P., Peters, P.J., et al. (2009). Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459, 262-265.
DOI
|
89 |
Hubert, C.G., Rivera, M., Spangler, L.C., Wu, Q., Mack, S.C., Prager, B.C., Couce, M., McLendon, R.E., Sloan, A.E., and Rich, J.N. (2016). A threedimensional organoid culture system derived from human glioblastomas recapitulates the hypoxic gradients and cancer stem cell heterogeneity of tumors found in vivo. Cancer Res. 76, 2465-2477.
DOI
|
90 |
Homem, C.C.F., Repic, M., and Knoblich, J.A. (2015). Proliferation control in neural stem and progenitor cells. Nat. Rev. Neurosci. 16, 647-659.
DOI
|
91 |
Tao, Y. and Zhang, S.C. (2016). Neural subtype specification from human pluripotent stem cells. Cell Stem Cell 19, 573-586.
DOI
|
92 |
Sloan, S.A., Darmanis, S., Huber, N., Khan, T.A., Birey, F., Caneda, C., Reimer, R., Quake, S.R., Barres, B.A., and Paşca, S.P. (2017). Human astrocyte maturation captured in 3D cerebral cortical spheroids derived from pluripotent stem cells. Neuron 95, 779-790.e6.
DOI
|
93 |
Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872.
DOI
|
94 |
Takahashi, K. and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
DOI
|