1 |
Miskinyte, G., Gr, M., Monni, E., Lam, M., Bengzon, J., Lindvall, O., Ahlenius, H., and Id, Z.K. (2018). Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers. PLoS One 13, e0204688.
DOI
|
2 |
Miyazaki, S., Yamato, E., and Miyazaki, J.I. (2004). Regulated expression of pdx-1 promotes in vitro differentiation of insulinproducing cells from embryonic stem cells. Diabetes 53, 1030-1037.
DOI
|
3 |
Nishiyama, A., Xin, L., Sharov, A.A., Thomas, M., Mowrer, G., Meyers, E., Piao, Y., Mehta, S., Yee, S., Nakatake, Y., et al. (2009). Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5, 420-433.
DOI
|
4 |
Osafune, K., Caron, L., Borowiak, M., Martinez, R.J., Fitz-Gerald, C.S., Sato, Y., Cowan, C.A., Chien, K.R., and Melton, D.A. (2008). Marked differences in differentiation propensity among human embryonic stem cell lines. Nat. Biotechnol. 26, 313-315.
DOI
|
5 |
Ozasa, S., Kimura, S., Ito, K., Ueno, H., Ikezawa, M., Matsukura, M., Yoshioka, K., Araki, K., Yamamura, K. ich, Abe, K., et al. (2007). Efficient conversion of ES cells into myogenic lineage using the geneinducible system. Biochem. Biophys. Res. Commun. 357, 957-963.
DOI
|
6 |
Pang, Z.P., Yang, N., Vierbuchen, T., Ostermeier, A., Fuentes, D.R., Yang, T.Q., Citri, A., Sebastiano, V., Marro, S., Südhof, T.C., et al. (2011). Induction of human neuronal cells by defined transcription factors. Nature 476, 220-223.
DOI
|
7 |
Raikwar, S.P., and Zavazava, N. (2012). PDX1-engineered embryonic stem cell-derived insulin producing cells regulate hyperglycemia in diabetic mice. Transplant. Res. 9, 277.
|
8 |
Walczak, M.P., Drozd, A.M., Stoczynska-Fidelus, E., Rieske, P., and Grzela, D.P. (2016). Directed differentiation of human iPSC into insulin producing cells is improved by induced expression of PDX1 and NKX6.1 factors in IPC progenitors. J. Transl. Med. 14, 341.
DOI
|
9 |
Weintraub, H., Tapscott, S.J., Davis, R.L., Thayer, M.J., Adam, M.A., Lassar, A.B., and Miller, A.D. (1989). Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc. Natl. Acad. Sci. 86, 5434-5438.
DOI
|
10 |
Wichterle, H., Lieberam, I., Porter, J.A., and Jessell, T.M. (2002). Directed differentiation of embryonic stem cells into motor neurons. Cell 110, 385-397.
DOI
|
11 |
Wonders, C., and Anderson, S.A. (2005). Cortical interneurons and their origins. Neuroscientist 11, 199-205.
DOI
|
12 |
Kim, K., Zhao, R., Doi, A., Ng, K., Unternaehrer, J., Cahan, P., Hongguang, H., Loh, Y.H., Aryee, M.J., Lensch, M.W., et al. (2011). Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat. Biotechnol. 29, 1117-1119.
DOI
|
13 |
Ionta, V., Liang, W., Kim, E.H., Rafie, R., Giacomello, A., Marban, E., and Cho, H.C. (2015). SHOX2 overexpression favors differentiation of embryonic stem cells into cardiac pacemaker cells, improving biological pacing ability. Stem Cell Reports 4, 129-142.
DOI
|
14 |
Jin, Y., Liu, Y., Li, Z., Santostefano, K., Shi, J., Zhang, X., Wu, D., Cheng, Z., Wu, W., Terada, N., et al. (2018). Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery. PLoS One 13, e0194895.
DOI
|
15 |
Kajiwara, M., Aoi, T., Okita, K., Takahashi, R., Inoue, H., Takayama, N., Endo, H., Eto, K., Toguchida, J., Uemoto, S., et al. (2012). Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells. Proc. Natl. Acad. Sci. USA 109, 12538-12543.
DOI
|
16 |
Yamamizu, K., Piao, Y., Sharov, A.A., Zsiros, V., Yu, H., Nakazawa, K., Schlessinger, D., and Ko, M.S.H. (2013). Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports 1, 545-559.
DOI
|
17 |
Wu, H., Xu, J., Pang, Z.P., Ge, W., Kim, K.J., Blanchi, B., Chen, C., Sudhof, T.C., and Sun, Y.E. (2007). Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc. Natl. Acad. Sci. 104, 13821-13826.
DOI
|
18 |
Xie, W., Schultz, M.D., Lister, R., Hou, Z., Rajagopal, N., Ray, P., Whitaker, J.W., Tian, S., Hawkins, R.D., Leung, D., et al. (2013). Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell 153, 1134-1148.
DOI
|
19 |
Xue, Y., Zhan, X., Sun, S., Karuppagounder, S.S., Xia, S., Dawson, V.L., Dawson, T.M., Laterra, J., Zhang, J., and Ying, M. (2018). Synthetic mRNAs drive highly efficient iPS cell differentiation to dopaminergic neurons. Stem Cells Transl. Med. 8, 112-123.
DOI
|
20 |
Koyanagi-Aoi, M., Ohnuki, M., Takahashi, K., Okita, K., Noma, H., Sawamura, Y., Teramoto, I., Narita, M., Sato, Y., Ichisaka, T., et al. (2013). Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells. Proc. Natl. Acad. Sci. USA 110, 20569-20574.
DOI
|
21 |
Kubo, A., Kim, Y.H., Irion, S., Kasuda, S., Takeuchi, M., Ohashi, K., Iwano, M., Dohi, Y., Saito, Y., Snodgrass, R., et al. (2010). The homeobox gene Hex regulates hepatocyte differentiation from embryonic stem cell-derived endoderm. Hepatology 51, 633-641.
DOI
|
22 |
Kubo, A., Stull, R., Takeuchi, M., Bonham, K., Gouon-Evans, V., Sho, M., Iwano, M., Saito, Y., Keller, G., and Snodgrass, R. (2011). Pdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm population. PLoS One 6, e24058.
DOI
|
23 |
Takayama, K., Inamura, M., Kawabata, K., Katayama, K., Higuchi, M., Tashiro, K., Nonaka, A., Sakurai, F., Hayakawa, T., Kusuda Furue, M., et al. (2012a). Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4 transduction. Mol. Ther. 20, 127-137.
DOI
|
24 |
Shiroi, A., Ueda, S., Ouji, Y., Saito, K., Moriya, K., Sugie, Y., Fukui, H., Ishizaka, S., and Yoshikawa, M. (2005). Differentiation of embryonic stem cells into insulin-producing cells promoted by Nkx2.2 gene transfer. World J. Gastroenterol. 11, 4161-4166.
DOI
|
25 |
Akiyama, T., Wakabayashi, S., Soma, A., Sato, S., Nakatake, Y., Oda, M., Murakami, M., Sakota, M., Chikazawa-Nohtomi, N., Ko, S.B.H., et al. (2016). Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells. Development 143, 3674-3685.
DOI
|
26 |
Albini, S., Coutinho, P., Malecova, B., Giordani, L., Savchenko, A., Forcales, S.V., and Puri, P.L. (2013). Epigenetic reprogramming of human embryonic stem cells into skeletal muscle cells and generation of contractile myospheres. Cell Rep. 3, 661-670.
DOI
|
27 |
Sun, A.X., Yuan, Q., Tan, S., Xiao, Y., Wang, D., Khoo, A.T.T., Sani, L., Tran, H.D., Kim, P., Chiew, Y.S., et al. (2016). Direct induction and functional maturation of forebrain GABAergic neurons from human pluripotent stem cells. Cell Rep. 16, 1942-1953.
DOI
|
28 |
Tabar, V., and Studer, L. (2014). Pluripotent stem cells in regenerative medicine: Challenges and recent progress. Nat. Rev. Genet. 15, 82-92.
DOI
|
29 |
Takahashi, K., Yamanaka, S., Zhang, Y., Li, Y., Feng, C., Li, X., Lin, L., Guo, L., Wang, H., Liu, C., et al. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
DOI
|
30 |
Takayama, K., Inamura, M., Kawabata, K., Tashiro, K., Katayama, K., Sakurai, F., Hayakawa, T., Furue, M.K., and Mizuguchi, H. (2011). Efficient and directive generation of two distinct endoderm lineages from human ESCs and iPSCs by differentiation stage-specific SOX17 transduction. PLoS One 6, e21780.
DOI
|
31 |
Takayama, K., Inamura, M., Kawabata, K., Sugawara, M., Kikuchi, K., Higuchi, M., Nagamoto, Y., Watanabe, H., Tashiro, K., Sakurai, F., et al. (2012b). Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1 transduction. J. Hepatol. 57, 628-636.
DOI
|
32 |
Hu, B.Y., Weick, J.P., Yu, J., Ma, L.X., Zhang, X.Q., Thomson, J.A., and Zhang, S.C. (2010). Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc. Natl. Acad. Sci. 107, 4335-4340.
DOI
|
33 |
Goparaju, S.K., Kohda, K., Ibata, K., Soma, A., Nakatake, Y., Akiyama, T., Wakabayashi, S., Matsushita, M., Sakota, M., Kimura, H., et al. (2017). Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors. Sci. Rep. 7, 42367.
DOI
|
34 |
Goto, K., Imamura, K., Komatsu, K., Mitani, K., Aiba, K., Nakatsuji, N., Inoue, M., Kawata, A., Yamashita, H., Takahashi, R., et al. (2017). Simple derivation of spinal motor neurons from ESCs/iPSCs using sendai virus vectors. Mol. Ther. Methods Clin. Dev. 4, 115-125.
DOI
|
35 |
Hester, M.E., Murtha, M.J., Song, S., Rao, M., Miranda, C.J., Meyer, K., Tian, J., Boulting, G., Schaffer, D.V., Zhu, M.X., et al. (2011). Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes. Mol. Ther. 19, 1905-1912.
DOI
|
36 |
Bai, F., Ho Lim, C., Jia, J., Santostefano, K., Simmons, C., Kasahara, H., Wu, W., Terada, N., and Jin, S. (2015). Directed differentiation of embryonic stem cells into cardiomyocytes by bacterial injection of defined transcription factors. Sci. Rep. 5, 15014.
DOI
|
37 |
Yang, N., Chanda, S., Marro, S., Ng, Y.H., Janas, J.A., Haag, D., Ang, C.E., Tang, Y., Flores, Q., Mall, M., et al. (2017). Generation of pure GABAergic neurons by transcription factor programming. Nat. Methods 14, 621-628.
DOI
|
38 |
Zhang, Y., Pak, C.H., Han, Y., Ahlenius, H., Zhang, Z., Chanda, S., Marro, S., Patzke, C., Acuna, C., Covy, J., et al. (2013). Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron 78, 785-798.
DOI
|
39 |
Ida, H., Akiyama, T., Ishiguro, K., Goparaju, S.K., Nakatake, Y., Chikazawa-nohtomi, N., Sato, S., Kimura, H., Yokoyama, Y., Nagino, M., et al. (2018). Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors. Stem Cell Res. Ther. 9, 277.
DOI
|
40 |
Inamura, M., Kawabata, K., Takayama, K., Tashiro, K., Sakurai, F., Katayama, K., Toyoda, M., Akutsu, H., Miyagawa, Y., Okita, H., et al. (2011). Efficient generation of hepatoblasts from human ES cells and iPS cells by transient overexpression of homeobox gene HEX. Mol. Ther. 19, 400-407.
DOI
|
41 |
Bernardo, A.S., Cho, C.H.H., Mason, S., Docherty, H.M., Pedersen, R.A., Vallier, L., and Docherty, K. (2009). Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic -cells. Stem Cells 27, 341-351.
DOI
|
42 |
Blyszczuk, P., Czyz, J., Kania, G., Wagner, M., Roll, U., St-Onge, L., and Wobus, A.M. (2003). Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulinproducing cells. Proc. Natl. Acad. Sci. USA 100, 998-1003.
DOI
|
43 |
Bock, C., Kiskinis, E., Verstappen, G., Gu, H., Boulting, G., Smith, Z.D., Ziller, M., Croft, G.F., Amoroso, M.W., Oakley, D.H., et al. (2011). Reference maps of human es and ips cell variation enable high-throughput characterization of pluripotent cell lines. Cell 144, 439-452.
DOI
|
44 |
Busskamp, V., Lewis, N.E., Guye, P., Ng, A.H., Shipman, S.L., Byrne, S.M., Sanjana, N.E., Murn, J., Li, Y., Li, S., et al. (2014). Rapid neurogenesis through transcriptional activation in human stem cells. Mol. Syst. Biol. 10, 760.
DOI
|
45 |
Liew, C.G., Shah, N.N., Briston, S.J., Shepherd, R.M., Khoo, C.P., Dunne, M.J., Moore, H.D., Cosgrove, K.E., and Andrews, P.W. (2008). PAX4 enhances beta-cell differentiation of human embryonic stem cells. PLoS One 3, e1783.
DOI
|
46 |
Kwon, C., Qian, L., Cheng, P., Nigam, V., Arnold, J., and Srivastava, D. (2009). A regulatory pathway involving Notch1/-catenin/Isl1 determines cardiac progenitor cell fate. Nat. Cell Biol. 11, 951-957.
DOI
|
47 |
Lee, S., Cuvillier, J.M., Lee, B., Shen, R., Lee, J.W., and Lee, S.K. (2012). Fusion protein Isl1-Lhx3 specifies motor neuron fate by inducing motor neuron genes and concomitantly suppressing the interneuron programs. Proc. Natl. Acad. Sci. 109, 3383-3388.
DOI
|
48 |
Chambers, S.M., Fasano, C.A., Papapetrou, E.P., Tomishima, M., Sadelain, M., and Studer, L. (2009). Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol. 27, 275-280.
DOI
|
49 |
Chanda, S., Ang, C.E., Davila, J., Pak, C., Mall, M., Lee, Q.Y., Ahlenius, H., Jung, S.W., Südhof, T.C., and Wernig, M. (2014). Generation of induced neuronal cells by the single reprogramming factor ASCL1. Stem Cell Reports 3, 282-296.
DOI
|
50 |
Li, X.J., Du, Z.W., Zarnowska, E.D., Pankratz, M., Hansen, L.O., Pearce, R.A., and Zhang, S.C. (2005). Specification of motoneurons from human embryonic stem cells. Nat. Biotechnol. 23, 215-221.
DOI
|
51 |
Lin, H.T., Kao, C.L., Lee, K.H., Chang, Y.L., Chiou, S.H., Tsai, F.T., Tsai, T.H., Sheu, D.C., Ho, L.L.T., and Ku, H.H. (2007). Enhancement of insulin-producing cell differentiation from embryonic stem cells using pax4-nucleofection method. World J. Gastroenterol. 13, 1672-1679.
DOI
|
52 |
Matsushita, M., Nakatake, Y., Arai, I., Ibata, K., Kohda, K., Goparaju, S.K., Murakami, M., Sakota, M., Chikazawa-Nohtomi, N., Ko, S.B.H., et al. (2017). Neural differentiation of human embryonic stem cells induced by the transgene-mediated overexpression of single transcription factors. Biochem. Biophys. Res. Commun. 490, 296-301.
DOI
|
53 |
Mercuri, E., Muntoni, F., Emery, A., Mercuri, E., Muntoni, F., Guglieri, M., Straub, V., Bushby, K., Lochmuller, H., Bushby, K., et al. (2013). Muscular dystrophies. Lancet (London, England) 381, 845-860.
DOI
|
54 |
Thoma, E.C., Wischmeyer, E., Offen, N., Maurus, K., Siren, A.L., Schartl, M., and Wagner, T.U. (2012). Ectopic expression of neurogenin 2 alone is sufficient to induce differentiation of embryonic stem cells into mature neurons. PLoS One 7, e38651.
DOI
|
55 |
Tanaka, A., Woltjen, K., Miyake, K., Hotta, A., Ikeya, M., Yamamoto, T., Nishino, T., Shoji, E., Sehara-Fujisawa, A., Manabe, Y., et al. (2013). Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling miyoshi myopathy in vitro. PLoS One 8, e61540.
DOI
|
56 |
Tao, Y., and Zhang, S.C. (2016). Neural subtype specification from human pluripotent stem cells. Cell Stem Cell 19, 573-586.
DOI
|
57 |
Theka, I., Caiazzo, M., Dvoretskova, E., Leo, D., Ungaro, F., Curreli, S., Manago, F., Dell'Anno, M.T., Pezzoli, G., Gainetdinov, R.R., et al. (2013). Rapid generation of functional dopaminergic neurons from human induced pluripotent stem cells through a single-step procedure using cell lineage transcription factors. Stem Cells Transl. Med. 2, 473-479.
DOI
|
58 |
Tomizawa, M., Shinozaki, F., Motoyoshi, Y., Sugiyama, T., Yamamoto, S., and Ishige, N. (2016). Transcription factors and medium suitable for initiating the differentiation of human-induced pluripotent stem cells to the hepatocyte lineage. J. Cell. Biochem. 117, 2001-2009.
DOI
|
59 |
Vierbuchen, T., Ostermeier, A., Pang, Z.P., Kokubu, Y., Südhof, T.C., and Wernig, M. (2010). Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463, 1035-1041.
DOI
|
60 |
Van, H.D., D'Amour, K.A., German, M.S., and Van Hoof, D. (2009). Derivation of insulin-producing cells from human embryonic stem cells. Stem Cell Res. 3, 73-87.
DOI
|
61 |
Darabi, R., Arpke, R.W., Irion, S., Dimos, J.T., Grskovic, M., Kyba, M., and Perlingeiro, R.C.R. (2012). Human ES- and iPS-derived myogenic progenitors restore DYSTROPHIN and improve contractility upon transplantation in dystrophic mice. Cell Stem Cell 10, 610-619.
DOI
|
62 |
Correa-Cerro, L.S., Piao, Y., Sharov, A.A., Nishiyama, A., Cadet, J.S., Yu, H., Sharova, L. V., Xin, L., Hoang, H.G., Thomas, M., et al. (2011). Generation of mouse ES cell lines engineered for the forced induction of transcription factors. Sci. Rep. 1, 167.
DOI
|
63 |
Darabi, R., Gehlbach, K., Bachoo, R.M., Kamath, S., Osawa, M., Kamm, K.E., Kyba, M., and Perlingeiro, R.C.R. (2008). Functional skeletal muscle regeneration from differentiating embryonic stem cells. Nat. Med. 14, 134-143.
DOI
|
64 |
Darabi, R., Santos, F.N.C., Filareto, A., Pan, W., Koene, R., Rudnicki, M.A., Kyba, M., and Perlingeiro, R.C.R. (2011). Assessment of the myogenic stem cell compartment following transplantation of Pax3/Pax7-induced embryonic stem cell-derived progenitors. Stem Cells 29, 777-790.
DOI
|
65 |
Davis, R.L., Weintraub, H., and Lassar, A.B. (1987). Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51, 987-1000.
DOI
|
66 |
Fonoudi, H., Yeganeh, M., Fattahi, F., Ghazizadeh, Z., Rassouli, H., Alikhani, M., Mojarad, B.A., Baharvand, H., Salekdeh, G.H., and Aghdami, N. (2013). ISL1 protein transduction promotes cardiomyocyte differentiation from human embryonic stem cells. PLoS One 8, e55577.
DOI
|
67 |
Dekel, I., Magal, Y., Pearson-White, S., Emerson, C.P., and Shani, M. (1992). Conditional conversion of ES cells to skeletal muscle by an exogenous MyoD1 gene. New Biol. 4, 217-224.
|