1 |
Mentch, S.J., and Locasale, J.W. (2016). One-carbon metabolism and epigenetics: understanding the specificity. Ann. New York Acad. Sci. 1363, 91-98.
DOI
|
2 |
Mentch, S.J., Mehrmohamadi, M., Huang, L., Liu, X., Gupta, D., Mattocks, D., Gomez Padilla, P., Ables, G., Bamman, M.M., Thalacker-Mercer, A.E., et al. (2015). Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism. Cell Metabol. 22, 861-873.
DOI
|
3 |
Mews, P., Donahue, G., Drake, A.M., Luczak, V., Abel, T., and Berger, S.L. (2017). Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory. Nature 546, 381-386.
DOI
|
4 |
Mihaylova, M.M., and Shaw, R.J. (2011). The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat. Cell Biol. 13, 1016-1023.
DOI
|
5 |
Hwang, I.Y., Kwak, S., Lee, S., Kim, H., Lee, S.E., Kim, J.H., Kim, Y.A., Jeon, Y.K., Chung, D.H., Jin, X., et al. (2016). Psat1-dependent fluctuations in alpha-Ketoglutarate affect the timing of ESC differentiation. Cell Metabol. 24, 494-501.
DOI
|
6 |
Katoh, Y., Ikura, T., Hoshikawa, Y., Tashiro, S., Ito, T., Ohta, M., Kera, Y., Noda, T., and Igarashi, K. (2011). Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein. Mol. Cell 41, 554-566.
DOI
|
7 |
Kim, J.E., Chen, J., and Lou, Z. (2008). DBC1 is a negative regulator of SIRT1. Nature 451, 583-586.
DOI
|
8 |
Kooistra, S.M., and Helin, K. (2012). Molecular mechanisms and potential functions of histone demethylases. Nat. Rev. Mol. Cell Biol. 13, 297-311.
DOI
|
9 |
Kottakis, F., Nicolay, B.N., Roumane, A., Karnik, R., Gu, H., Nagle, J.M., Boukhali, M., Hayward, M.C., Li, Y.Y., Chen, T., et al. (2016). LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature 539, 390-395.
DOI
|
10 |
Kryukov, G.V., Wilson, F.H., Ruth, J.R., Paulk, J., Tsherniak, A., Marlow, S.E., Vazquez, F., Weir, B.A., Fitzgerald, M.E., Tanaka, M., et al. (2016). MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells. Science 351, 1214-1218.
DOI
|
11 |
Lau, A.W., Liu, P., Inuzuka, H., and Gao, D. (2014). SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation. Am. J. Cancer Res. 4, 245-255.
|
12 |
Hay, N. (2016). Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy? Nat. Rev. Cancer 16, 635-649.
DOI
|
13 |
Huang, W.C., and Chen, C.C. (2005). Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. Mol. Cell. Biol. 25, 6592-6602.
DOI
|
14 |
Baba, A., Ohtake, F., Okuno, Y., Yokota, K., Okada, M., Imai, Y., Ni, M., Meyer, C.A., Igarashi, K., Kanno, J., et al. (2011). PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B. Nat. Cell Biol. 13, 668-675.
DOI
|
15 |
Badeaux, A.I., and Shi, Y. (2013). Emerging roles for chromatin as a signal integration and storage platform. Nat. Rev. Mol. Cell Biol. 14, 211-224.
DOI
|
16 |
Boland, M.J., Nazor, K.L., and Loring, J.F. (2014). Epigenetic regulation of pluripotency and differentiation. Circ. Res. 115, 311-324.
DOI
|
17 |
Cai, L., Sutter, B.M., Li, B., and Tu, B.P. (2011). Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes. Mol. Cell 42, 426-437.
DOI
|
18 |
Cha, T.L., Zhou, B.P., Xia, W., Wu, Y., Yang, C.C., Chen, C.T., Ping, B., Otte, A.P., and Hung, M.C. (2005). Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science 310, 306-310.
DOI
|
19 |
Canto, C., Gerhart-Hines, Z., Feige, J.N., Lagouge, M., Noriega, L., Milne, J.C., Elliott, P.J., Puigserver, P., and Auwerx, J. (2009). AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 458, 1056-1060.
DOI
|
20 |
Carey, B.W., Finley, L.W., Cross, J.R., Allis, C.D., and Thompson, C.B. (2015). Intracellular alpha-ketoglutarate maintains the pluripotency of embryonic stem cells. Nature 518, 413-416.
DOI
|
21 |
Chang, H.C., and Guarente, L. (2014). SIRT1 and other sirtuins in metabolism. Trends Endocrinol. Metabol. 25, 138-145.
DOI
|
22 |
Pan, M., Reid, M.A., Lowman, X.H., Kulkarni, R.P., Tran, T.Q., Liu, X., Yang, Y., Hernandez-Davies, J.E., Rosales, K.K., Li, H., et al. (2016). Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation. Nat. Cell Biol. 18, 1090-1101.
DOI
|
23 |
Sutendra, G., Kinnaird, A., Dromparis, P., Paulin, R., Stenson, T.H., Haromy, A., Hashimoto, K., Zhang, N., Flaim, E., and Michelakis, E.D. (2014). A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation. Cell 158, 84-97.
DOI
|
24 |
TeSlaa, T., Chaikovsky, A.C., Lipchina, I., Escobar, S.L., Hochedlinger, K., Huang, J., Graeber, T.G., Braas, D., and Teitell, M.A. (2016). alpha-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells. Cell Metabol. 24, 485-493.
DOI
|
25 |
Wellen, K.E., Hatzivassiliou, G., Sachdeva, U.M., Bui, T.V., Cross, J.R., and Thompson, C.B. (2009). ATP-citrate lyase links cellular metabolism to histone acetylation. Science 324, 1076-1080.
DOI
|
26 |
Wise, D.R., and Thompson, C.B. (2010). Glutamine addiction: a new therapeutic target in cancer. Trends Biochem. Sci. 35, 427-433.
DOI
|
27 |
Zhao, W., Kruse, J.P., Tang, Y., Jung, S.Y., Qin, J., and Gu, W. (2008). Negative regulation of the deacetylase SIRT1 by DBC1. Nature 451, 587-590.
DOI
|
28 |
Pavlova, N.N., and Thompson, C.B. (2016). The emerging hallmarks of cancer metabolism. Cell Metabol. 23, 27-47.
DOI
|
29 |
Portela, A., and Esteller, M. (2010). Epigenetic modifications and human disease. Nat. Biotechnol. 28, 1057-1068.
DOI
|
30 |
Reid, M.A., Dai, Z., and Locasale, J.W. (2017). The impact of cellular metabolism on chromatin dynamics and epigenetics. Nat. Cell Biol. 19, 1298-1306.
DOI
|
31 |
Li, S., Swanson, S.K., Gogol, M., Florens, L., Washburn, M.P., Workman, J.L., and Suganuma, T. (2015). Serine and SAM responsive complex SESAME regulates histone modification crosstalk by sensing cellular metabolism. Mol. Cell 60, 408-421.
DOI
|
32 |
Shyh-Chang, N., Locasale, J.W., Lyssiotis, C.A., Zheng, Y., Teo, R.Y., Ratanasirintrawoot, S., Zhang, J., Onder, T., Unternaehrer, J.J., Zhu, H., et al. (2013). Influence of threonine metabolism on Sadenosylmethionine and histone methylation. Science 339, 222-226.
DOI
|
33 |
Stopa, N., Krebs, J.E., and Shechter, D. (2015). The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond. Cell. Mol. Life Sci. 72, 2041-2059.
DOI
|
34 |
Sun, L., Huang, Y., Wei, Q., Tong, X., Cai, R., Nalepa, G., and Ye, X. (2015). Cyclin E-CDK2 protein phosphorylates plant homeodomain finger protein 8 (PHF8). and regulates its function in the cell cycle. J. Biol. Chem. 290, 4075-4085.
DOI
|
35 |
Nin, V., Escande, C., Chini, C.C., Giri, S., Camacho-Pereira, J., Matalonga, J., Lou, Z., and Chini, E.N. (2012). Role of deleted in breast cancer 1 (DBC1). protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase. J. Biol. Chem. 287, 23489-23501.
DOI
|
36 |
Lee, J.V., Carrer, A., Shah, S., Snyder, N.W., Wei, S., Venneti, S., Worth, A.J., Yuan, Z.F., Lim, H.W., Liu, S., et al. (2014). Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metabol. 20, 306-319.
DOI
|
37 |
Liu, F., Zhao, X., Perna, F., Wang, L., Koppikar, P., Abdel-Wahab, O., Harr, M.W., Levine, R.L., Xu, H., Tefferi, A., et al. (2011). JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell 19, 283-294.
DOI
|
38 |
Mattaini, K.R., Sullivan, M.R., and Vander Heiden, M.G. (2016). The importance of serine metabolism in cancer. J. Cell Biol. 214, 249-257.
DOI
|