The Signaling Mechanism of Contraction Induced by ATP and UTP in Feline Esophageal Smooth Muscle Cells |
Kwon, Tae Hoon
(Department of Pharmacology, College of Pharmacy, Chung-Ang University)
Jung, Hyunwoo (Department of Pharmacology, College of Pharmacy, Chung-Ang University) Cho, Eun Jeong (Department of Pharmacology, College of Pharmacy, Chung-Ang University) Jeong, Ji Hoon (Department of Pharmacology, College of Medicine, Chung-Ang University) Sohn, Uy Dong (Department of Pharmacology, College of Pharmacy, Chung-Ang University) |
1 | Fredholm, B.B., Abbracchio, M.P., Burnstock, G., Daly, J.W., Harden, T.K., Jacobson, K.A., Leff, P., and Williams, M. (1994). Nomenclature and classification of purinoceptors. Pharmacol. Rev. 46, 143-156. |
2 | Fredholm, B.B., Abbracchio, M.P., Burnstock, G., Dubyak, G.R., Harden, T.K., Jacobson, K.A., Schwabe, U., and Williams, M. (1997). Towards a revised nomenclature for P1 and P2 receptors. Trends Pharmacol. Sci.18, 79-82. |
3 | Gilman, A.G. (1987). G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56, 615-649. DOI ScienceOn |
4 | Haeberle, J.R., Hathaway, D.R., and DePaoli-Roach, A.A. (1985). Dephosphorylation of myosin by the catalytic subunit of a type-2 phosphatase produces relaxation of chemically skinned uterine smooth muscle. J. Biol. Chem. 260, 9965-9968. |
5 | Harden, T.K., Boyer, J.L., and Nicholas, R.A. (1995). P2-purinergic receptors: subtype-associated signaling responses and structure. Annu. Rev. Pharmacol.Toxicol. 35, 541-579. DOI ScienceOn |
6 | Horowitz, A., Clement-Chomienne, O., Walsh, M.P., and Morgan, K.G. (1996). Epsilon-isoenzyme of protein kinase C induces a Ca(2+)-independent contraction in vascular smooth muscle. Am. J. Physiol. 271, C589-594. DOI |
7 | Huang, J., Zhou, H., Mahavadi, S., Sriwai, W., Lyall, V., and Murthy, K.S. (2005). Signaling pathways mediating gastrointestinal smooth muscle contraction and MLC20 phosphorylation by motilin receptors. Am. J. Physiol. Gastrointest. Liver Physiol. 288, G23-31. DOI ScienceOn |
8 | Ijzer, J., Kisjes, J.R., Penning, L.C., Rothuizen, J., and van, den, Ingh, T.S. (2009). The progenitor cell compartment in the feline liver: an (immuno)histochemical investigation. Vet. Pathol. 46, 614-621. DOI ScienceOn |
9 | Ikebe, M., Hartshorne, D.J., and Elzinga, M. (1987). Phosphorylation of the 20,000-dalton light chain of smooth muscle myosin by the calcium-activated, phospholipid-dependent protein kinase. Phosphorylation sites and effects of phosphorylation. J. Biol. Chem. 262, 9569-9573. |
10 | Jiang, L.H., Kim, M., Spelta, V., Bo, X., Surprenant, A., and North, R.A. (2003). Subunit arrangement in P2X receptors. J. Neurosci. 23, 8903-8910. |
11 | Lazarowski, E.R., and Harden, T.K. (1994). Identification of a uridine nucleotide-selective G-protein-linked receptor that activates phospholipase-C. J. Biol. Chem. 269, 11830-11836. |
12 | Lechleiter, J., Hellmiss, R., Duerson, K., Ennulat, D., David, N., Clapham, D., and Peralta, E. (1990). Distinct sequence elements control the specificity of G protein activation by muscarinic acetylcholine receptor subtypes. EMBO J. 13, 4381-4390. |
13 | Lee, H.Y., Bardini, M., and Burnstock, G. (2000). P2X receptor immunoreactivity in the male genital organs of the rat. Cell Tissue Res. 300, 321-330. DOI |
14 | Lefebvre, R.A. (1993). Non-adrenergic non-cholinergic neurotransmission in the proximal stomach. Gen. Pharmac. 24, 257-266. DOI ScienceOn |
15 | Lundberg, J.M. (1996). Pharmacology of cotransmission in the autonomic nervous system: integrative aspects on amines, neuropeptides, adenosine triphosphate, amino acids and nitric oxide. Pharmacol. Rev. 48, 113-178. |
16 | Matsuda, N.M., and Miller, S.M. (2010). Non-adrenergic noncholinergic inhibition of gastrointestinal smooth muscle and its intracellular mechanism(s). Fundam. Clin. Pharmacol. 24, 261-268. |
17 | Murthy, K.S., McHenry, L., Grider, J.R., and Makhlouf, G.M. (1995). Adenosine A1 and A2b receptors coupled to distinct interactive signaling pathways in intestinal muscle cells. J. Pharmacol. Exp. Ther. 274, 300-306. |
18 | Nam, Y.S., Suh, J.S., Song, H.J., and Sohn, U.D. (2013). Signaling pathway of lysophosphatidic Acid-induced contraction in feline esophageal smooth muscle cells. Korean J. Physiol. Pharmacol. 17, 139-147. DOI ScienceOn |
19 | Murthy, K.S., and Makhlouf, G.M. (1998). Coexpression of ligandgated P2X and G protein-coupled P2Y receptors in smooth muscle. Preferential activation of P2Y receptors coupled to phospholipase C (PLC)-beta1 via Galphaq/11 and to PLC-beta3 via Gbetagammai3. J. Biol. Chem. 273, 4695-4704. DOI ScienceOn |
20 | Murthy, K.S., Zhou, H., Grider, J.R., Brautigan, D.L., Eto, M., and Makhlouf, G.M. (2003). Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase /myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway. Biochem. J. 374, 145-155. DOI |
21 | Puetz, S., Lubomirov, L.T., and Pfitzer, G. (2009). Regulation of Smooth Muscle Contraction by Small GTPases. Physiology 24, 342-356. DOI ScienceOn |
22 | Ralevic, V., and Burnstock, G. (1998). Receptors for purines and pyrimidines. Pharmacol. Rev. 50, 413-492. |
23 | Shim, J.O., Shin, C.Y., Lee, T.S., Yang, S.J., An, J.Y., Song, H.J., Kim, T.H., Huh, I.H., and Sohn, U.D. (2002). Signal transduction mechanism via adenosine A1 receptor in the cat esophageal smooth muscle cells. Cell. Signal. 14, 365-372. DOI ScienceOn |
24 | Sohn, U.D., Harnett, K.M., De Petris, G., Behar, J., and Biancani, P. (1993). Distinct muscarinic receptors, G proteins and phospholipases in esophageal and lower esophageal sphincter circular muscle. J. Pharmacol. Exp. Ther. 267, 1205-1214. |
25 | Somlyo, A.P., and Somlyo, A.V. (1994). Signal transduction and regulation in smooth muscle. Nature 372, 231-236. DOI ScienceOn |
26 | Sohn, U.D., Han, B., Tashjian, A.H., Jr., Behar, J., and Biancani, P. (1995a). Agonist-independent, muscle-type-specific signal-transduction pathways in cat esophageal and lower eso-phageal sphincter circular smooth-muscle. J. Pharmacol. Exp. Ther. 273, 482-491. |
27 | Sohn, U.D., Han, B., Tashjian, A.H., Jr., Behar, J., and Biancani, P. (1995b). Agonist-independent, muscle-type-specific signal transduction pathways in cat esophageal and lower esophageal sphincter circular smooth muscle. J. Pharmacol Exp. Ther. 273, 482-491. |
28 | Sohn, U.D., Harnett, K.M., Cao, W., Rich, H., Kim, N., Behar, J., and Biancani, P. (1997). Acute experimental esophagitis activates a second signal transduction pathway in cat smooth muscle from the lower esophageal sphincter. J. Pharmacol. Exp. Ther. 283, 1293-1304. |
29 | Surprenant, A. and North, R.A. (2009) Signaling at Purinergic P2X Receptors. Annu. Rev. Physiol. 71, 333-359. DOI ScienceOn |
30 | van der Weyden, L., Conigrave, A.D., and Morris, M.B. (2000). Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptor. Immunol. Cell Biol. 78, 369-374. DOI ScienceOn |
31 | Vantrappen, G., Janssens, J., Coremans, G. and Jian, R. (1986). Gastrointestinal motility disorders. Dig. Dis. Sci. 31, 5S-25S. DOI |
32 | Webb, R.C. (2003). Smooth muscle contraction and relaxation. Adv. Physiol. Educ. 27, 201-206. DOI |
33 | Yang, S.J., An, J.Y., Shim, J.O., Park, C.H., Huh, I.H., and Sohn, U.D. (2000). The mechanism of contraction by 2-chloroadenosine in cat detrusor muscle cells. J. Urol. 163, 652-658. DOI ScienceOn |
34 | Billah, M.M., and Anthes, J.C. (1990). The regulation and cellular functions of phosphatidylcholine hydrolysis. Biochem J. 269, 281-291. DOI |
35 | Yiangou, Y., Facer, P., Baecker, P.A., Ford, A.P., Knowles, C.H., Chan, C.L.H., Williams, N.S., and Anand, P. (2001). ATP-gated ion channel P2X(3) is increased in human inflammatory bowel disease. Neurogastroenterol. Motil. 13, 365-369. DOI ScienceOn |
36 | Abbracchio, M.P., Burnstock, G., Boeynaems, J.M., Barnard, E.A., Boyer, J.L., Kennedy, C., Knight, G.E., Fumagalli, M., Gachet, C., Jacobson, K.A., et al. (2006). International union of pharmacology LVIII: Update on the P2Y G protein-coupled nucleotide receptors: From molecular mechanisms and pathophysiology to therapy. Pharmacol. Rev. 58, 281-341. DOI ScienceOn |
37 | Akbar, G.K., Dasari, V.R., Webb, T.E., Ayyanathan, K., Pillarisetti, K., Sandhu, A.K., Athwal, R.S., Daniel, J.L., Ashby, B., Barnard, E.A., et al. (1996). Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells. J. Biol. Chem. 271, 18363-18367. DOI ScienceOn |
38 | Bialojan, C., Ruegg, J.C., and DiSalvo, J. (1987). A myosin phosphatase modulates contractility in skinned smooth muscle. Pflugers Arch. 410, 304-312. DOI |
39 |
Biancani, P., Hillemeier, C., Bitar, K.N., and Makhlouf, G.M. (1987). Contraction mediated by |
40 |
Bitar, K.N., Bradford, P.G., Putney, J.W., Jr., and Makhlouf, G.M. (1986). Stoichiometry of contraction and |
41 | Burnstock, G. (2006). Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol. Rev. 58, 58-86. DOI ScienceOn |
42 | Chang, K., Hanaoka, K., Kumada, M., and Takuwa, Y. (1995). Molecular cloning and functional analysis of a novel P2 nucleotide receptor. J. Biol. Chem. 270, 26152-26158. DOI ScienceOn |
43 | Burnstock, G. (2008). Purinergic receptors as future targets for treatment of functional GI disorders. Gut 57, 1193-1194. DOI ScienceOn |
44 | Burnstock, G., Campbell, G., Satchell, D., and Smythe, A. (1997). Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by nonadrenergic inhibitory nerves in the gut (Reprinted from Brit J Pharmacol, vol 40, pp 668-688, 1970). Br. J. Pharmacol.120, 337-357. DOI ScienceOn |
45 |
Cao, W., Chen, Q., Sohn, U.D., Kim, N., Kirber, M.T., Harnett, K.M., Behar, J., and Biancani, P. (2001). |
46 | Cho, Y.R., Jang, H.S., Kim, W., Park, S.Y., and Sohn, U.D. (2010). P2X and P2Y receptors mediate contraction induced by electrical field stimulation in feline esophageal smooth muscle. Korean J. Physiol. Pharmacol.14, 311-316. DOI ScienceOn |
47 | Cowen, D.S., Sanders, M., and Dubyak, G. (1990). P2-purinergic receptors activate a guanine nucleotide-dependent phospholipase C in membranes from HL-60 cells. Biochim. Biophys. Acta 1053, 195-203. DOI ScienceOn |
48 | Dubyak, G.R., and el-Moatassim, C. (1993). Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am. J. Physiol. 265, C577-606. DOI |
49 | Fabiato, A., and Fabiato, F. (1979). Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. J. Physiol. (Paris) 75, 463-505. |
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