Transmembrane Helix of Novel Oncogene with Kinase-Domain (NOK) Influences Its Oligomerization and Limits the Activation of RAS/MAPK Signaling |
Li, Ying-Hua
(Institute of Biomedicine and School of Medicine, Tsinghua University)
Wang, Yin-Yin (Institute of Biomedicine and School of Medicine, Tsinghua University) Zhong, Shan (Institute of Biomedicine and School of Medicine, Tsinghua University) Rong, Zhi-Li (Institute of Biomedicine and School of Medicine, Tsinghua University) Ren, Yong-Ming (Institute of Biomedicine and School of Medicine, Tsinghua University) Li, Zhi-Yong (Institute of Biomedicine and School of Medicine, Tsinghua University) Zhang, Shu-Ping (Institute of Biomedicine and School of Medicine, Tsinghua University) Chang, Zhi-Jie (Institute of Biomedicine and School of Medicine, Tsinghua University) Liu, Li (Institute of Biomedicine and School of Medicine, Tsinghua University) |
1 | Ozaki, K., Miyazaki, S., Tanimura, S., and Kohno, M. (2005). Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms. J. Cell Sci. 118, 5861-5871 DOI ScienceOn |
2 | Schlessinger, J. (2002). Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 110, 669-672 DOI ScienceOn |
3 | Smith, K.M., Yacobi, R., and Van Etten, R.A. (2003). Autoinhibition of Bcr-Abl through its SH3 domain. Mol. Cell 12, 27-37 DOI ScienceOn |
4 | Yu, X., Sharma, K.D., Takahashi, T., Iwamoto, R., and Mekada, E. (2002). Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling. Mol. Biol. Cell 13, 2547-2557 DOI PUBMED ScienceOn |
5 | Kimbro, K.S., Duschene, K., Willard, M., Moore, J.A., and Freeman, S. (2008). A novel gene STYK1/NOK is upregulated in estrogen receptor-alpha negative estrogen receptorbeta positive breast cancer cells following estrogen treatment. Mol. Biol. Rep. 35, 23-27 DOI PUBMED ScienceOn |
6 | Mohammadi, M., Honegger, A., Sorokin, A., Ullrich, A., Schlessinger, J., and Hurwitz, D.R. (1993). Aggregationinduced activation of the epidermal growth factor receptor protein tyrosine kinase. Biochemistry 32, 8742-8748 DOI PUBMED ScienceOn |
7 | Manning, G., Whyte, D.B., Martinez, R., Hunter, T., and Sudarsanam, S. (2002). The protein kinase complement of the human genome. Science 298, 1912-1934 DOI PUBMED ScienceOn |
8 | Pluk, H., Dorey, K., and Superti-Furga, G. (2002). Autoinhibition of c-Abl. Cell 108, 247-259 DOI ScienceOn |
9 | Guy, P.M., Platko, J.V., Cantley, L.C., Cerione, R.A., and Carraway, K.L., 3rd. (1994). Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity. Proc. Natl. Acad. Sci. USA 91, 8132-8136 DOI ScienceOn |
10 | Li, Y.H., Chang, Z.J., and Liu, L. (2008a). NOK interacts with Akt and enhances its activation. Prog. Biochem. Biophys. 35, 29-34 |
11 | Robinson, D.R., Wu, Y.M., and Lin, S.F. (2000). The protein tyrosine kinase family of the human genome. Oncogene 19, 5548-5557 DOI PUBMED |
12 | Jiang, G., and Hunter, T. (1999). Receptor signaling: When dimerization is not enough. Curr. Biol. 9, R568-R571 DOI ScienceOn |
13 | Bartkiewicz, M., Houghton, A., and Baron, R. (1999). Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor. J. Biol. Chem. 274, 30887-30895 DOI PUBMED |
14 | Amachika, T., Kobayashi, D., Moriai, R., Tsuji, N., and Watanabe, N. (2007). Diagnostic relevance of overexpressed mRNA of novel oncogene with kinase-domain (NOK) in lung cancers. Lung Cancer 56, 337-340 DOI PUBMED ScienceOn |
15 | Tong, Q., Xing, S., and Jhiang, S.M. (1997). Leucine zippermediated dimerization is essential for the oncogenic activity. J. Biol. Chem. 272, 9043-9047 DOI ScienceOn |
16 | Hubbard, S.R. (2002). Autoinhibitory mechanisms in receptor tyrosine kinases. Front Biosci. 7, d330-340 DOI PUBMED |
17 | Fan, P.D., Cong, F., and Goff, S.P. (2003). Homo- and heterooligomerization of the c-Abl kinase and Abelson-interactor-1. Cancer Res. 63, 873-877 PUBMED |
18 | Kani, K., Warren, C.M., Kaddis, C.S., Loo, J.A., and Landgraf, R. (2005). Oligomers of have two distinct interfaces that differ in their sensitivity to disruption by heregulin. J. Biol. Chem. 280, 8238-8247 DOI PUBMED ScienceOn |
19 | McWhirter, J.R., Galasso, D.L., and Wang, J.Y. (1993). A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins. Mol. Cell. Biol. 13, 7587-7595 DOI PUBMED |
20 | Blume-Jensen, P., and Hunter, T. (2001). Oncogenic kinase signalling. Nature 411, 355-365 DOI PUBMED ScienceOn |
21 | Brennan, P.J., Kumagai, T., Berezov, A., Murali, R., and Greene, M.I. (2000). HER2/neu: mechanisms of dimerization/oligomerization. Oncogene 19, 6093-6101 DOI PUBMED |
22 | Chen, Y., Li, Y.H., Chen, X.P., Gong, L.M., Zhang, S.P., Chang, Z.J., Zhang, X.F., Fu, X.Y., and Liu, L. (2005). Point mutation at single tyrosine residue of novel oncogene NOK abrogates tumorigenesis in nude mice. Cancer Res 65, 10838-10846 DOI PUBMED ScienceOn |
23 | Clayton, A.H., Walker, F., Orchard, S.G., Henderson, C., Fuchs, D., Rothacker, J., Nice, E.C., and Burgess, A.W. (2005). Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis. J. Biol. Chem. 280, 30392-30399 DOI PUBMED ScienceOn |
24 | Moriai, R., Kobayashi, D., Amachika, T., Tsuji, N., and Watanabe, N. (2006). Diagnostic relevance of overexpressed NOK mRNA in breast cancer. Anticancer Res. 26, 4969-4973 |
25 | Li, Y.H., Zhong, S., Rong, Z.L., Ren, Y.M., Li, Z.Y., Zhang, S.P., Chang, Z., and Liu, L. (2007). The carboxyl terminal tyrosine 417 residue of NOK has an autoinhibitory effect on NOKmediated signaling transductions. Biochem. Biophys. Res. Commun. 356, 444-449 DOI PUBMED ScienceOn |
26 | Simpson, J.C., Wellenreuther, R., Poustka, A., Pepperkok, R., and Wiemann, S. (2000). Systematic subcellular localization of novel proteins identified by large scale cDNA sequencing. EMBO Rep. 1, 287-292 DOI PUBMED ScienceOn |
27 | Li, E., and Hristova, K. (2006). Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies. Biochemistry 45, 6241-6251 DOI ScienceOn |
28 | Li, Y.H., Rong, Y., Chang, Z J., and Liu, L. (2008b). NOK activates STAT3 signaling by a JAK2-dependent mechanism. Prog. Biochem. Biophys. 35, 143-150 |
29 | Liu, L., Yu, X.Z., Li, T.S., Song, L.X., Chen, P.L., Suo, T.L., Li, Y.H., Wang, S.D., Chen, Y., Ren, Y.M., et al. (2004). A novel protein tyrosine kinase NOK that shares homology with platelet- derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice. Cancer Res. 64, 3491-3499 DOI ScienceOn |
30 | Ye, X., Ji, C., Huang, Q., Cheng, C., Tang, R., Xu, J., Zeng, L., Dai, J., Wu, Q., Gu, S., et al. (2003). Isolation and characterization of a human putative receptor protein kinase cDNA STYK1. Mol. Biol. Rep. 30, 91-96 DOI PUBMED ScienceOn |