1 |
Atwood, C. S., Moir, R. D., Huang, X., Scarpa, R. C., Bacarra, N. M., et al. (1998) Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. J. Biol. Chem. 273, 12817-12826
DOI
ScienceOn
|
2 |
Curtain, C. C., Ali, F., Volitakis, I., Cherny, R. A., Norton, R. S., et al. (2001) Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membranepenetrating structure containing superoxide dismutase-like subunits. J. Biol. Chem. 276, 20466-20473
DOI
ScienceOn
|
3 |
de la Torre, J. C. (2004) Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics. Lancet Neurol. 3, 184-190
DOI
ScienceOn
|
4 |
Hensley, K., Carney, J. M., Mattson, M. P., Aksenova, M., Harris, M., et al. (1994) A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. Proc. Natl. Acad. Sci. USA 91, 3270-3274
|
5 |
Inoue, K., Masuko-Hongo, K., Okamoto, M., and Nishioka, K. (2005) Induction of vascular endothelial growth factor and matrix metalloproteinase-3 (stromelysin) by interleukin-1 in human articular chondrocytes and synoviocytes. Rheumatol. Int. 26, 93-98
DOI
ScienceOn
|
6 |
Martin, F., Linden, T., Katschinski, D. M., Oehme, F., Flamme, I., et al. (2005) Copper-dependent activation of hypoxiainducible factor (HIF)-1: implications for ceruloplasmin regulation. Blood 105, 4613-4619
DOI
ScienceOn
|
7 |
Masters, C. L., Multhaup, G., Simms, G., Pottgiesser, J., Martins, R. N., et al. (1985) Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels. EMBO J. 4, 2757-2763
|
8 |
Storkebaum, E. and Carmeliet, P. (2004) VEGF: a critical player in neurodegeneration. J. Clin. Invest. 113, 14-18
DOI
|
9 |
Vigo-Pelfrey, C., Lee, D., Keim, P., Lieberburg, I., and Schenk, D. B. (1993) Characterization of beta-amyloid peptide from human cerebrospinal fluid. J. Neurochem. 61, 1965-1968
DOI
ScienceOn
|
10 |
Kuroki, M., Voest, E. E., Amano, S., Beerepoot, L. V., Takashima, S., et al. (1996) Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo. J. Clin. Invest. 98, 1667-1675
DOI
ScienceOn
|
11 |
Stuerenburg, H. J. (2000) CSF copper concentrations, bloodbrain barrier function, and coeruloplasmin synthesis during the treatment of Wilson's disease. J. Neural. Transm. 107, 321-329
DOI
|
12 |
Nan, B., Lin, P., Lumsden, A. B., Yao, Q., and Chen, C. (2005) Effects of TNF-alpha and curcumin on the expression of thrombomodulin and endothelial protein C receptor in human endothelial cells. Thromb. Res. 115, 417-426
DOI
ScienceOn
|
13 |
Tarkowski, E., Issa, R., Sjogren, M., Wallin, A., Blennow, K., et al. (2002) Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia. Neurobiol. Aging 23, 237-243
DOI
ScienceOn
|
14 |
Lovell, M. A., Robertson, J. D., Teesdale, W. J., Campbell, J. L., and Markesbery, W. R. (1998) Copper, iron and zinc in Alzheimer's disease senile plaques. J. Neurol. Sci. 158, 47-52
DOI
ScienceOn
|
15 |
Opazo, C., Huang, X., Cherny, R. A., Moir, R. D., Roher, A. E., et al. (2002) Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). J. Biol. Chem. 277, 40302-40308
DOI
ScienceOn
|
16 |
Kosmidou, I., Xagorari, A., Roussos, C., and Papapetropoulos, A. (2001) Reactive oxygen species stimulate VEGF production from C(2)C(12) skeletal myotubes through a PI3K/Akt pathway. Am. J. Physiol. Lung Cell Mol. Physiol. 280, L585-592
|
17 |
Yang, S. P., Bae, D. G., Kang, H. J., Gwag, B. J., Gho, Y. S., et al. (2004) Co-accumulation of Vascular endothelial growth factor with beta-amyloid in the brain of patients with Alzheimer's disease. Neurobiol. Aging 25, 283-290
DOI
ScienceOn
|
18 |
Jin, K. L., Mao, X. O., and Greenberg, D. A. (2000b) Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc. Natl. Acad. Sci. USA 97, 10242-10247
|
19 |
Parihar, M. S. and Hemnani, T. (2004) Alzheimer's disease pathogenesis and therapeutic interventions. J. Clin. Neurosci. 11, 456-467
DOI
ScienceOn
|
20 |
Sinor, A. D., Irvin, S. M., Cobbs, C. S., Chen, J., Graham, S. H., et al. (1998) Hypoxic induction of vascular endothelial growth factor (VEGF) protein in astroglial cultures. Brain Res. 812, 289-291
DOI
|
21 |
Yang, S. P., Kwon, B. O., Gho, Y. S., and Chae, C. B. (2005) Specific interaction of VEGF165 with beta-amyloid, and its protective effect on beta-amyloid-induced neurotoxicity. J. Neurochem. 93, 118-127
DOI
ScienceOn
|
22 |
Jin, K. L., Mao, X. O., and Greenberg, D. A. (2000a) Vascular endothelial growth factor rescues HN33 neural cells from death induced by serum withdrawal. J. Mol. Neurosci. 14, 197-203
DOI
ScienceOn
|
23 |
Kalaria, R. N., Cohen, D. L., Premkumar, D. R., Nag, S., La- Manna, J. C., et al. (1998) Vascular endothelial growth factor in Alzheimer's disease and experimental cerebral ischemia. Brain Res. Mol. Brain Res. 62, 101-105
DOI
|
24 |
Zhu, J. W., Yu, B. M., Ji, Y. B., Zheng, M. H., and Li, D. H. (2002) Upregulation of vascular endothelial growth factor by hydrogen peroxide in human colon cancer. World J. Gastroenterol. 8, 153-157
DOI
|
25 |
Lee, H. J., Hammond, D. N., Large, T. H., Roback, J. D., Sim, J. A., et al. (1990) Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice. J. Neurosci. 10, 1779-1787
DOI
|
26 |
Asano-Kato, N., Fukagawa, K., Okada, N., Kawakita, T., Takano, Y., et al. (2005) TGF-beta1, IL-1beta, and Th2 cytokines stimulate vascular endothelial growth factor production from conjunctival fibroblasts. Exp. Eye Res. 80, 555-560
DOI
ScienceOn
|
27 |
Ferrara, N., Gerber, H. P., and LeCouter, J. (2003) The biology of VEGF and its receptors. Nat. Med. 9, 669-676
|
28 |
Huang, X., Cuajungco, M. P., Atwood, C. S., Hartshorn, M. A., Tyndall, J. D., et al. (1999b) Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction. J. Biol. Chem. 274, 37111-37116
DOI
ScienceOn
|
29 |
Barnham, K. J., Haeffner, F., Ciccotosto, G. D., Curtain, C. C., Tew, D., et al. (2004) Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid. FASEB J. 18, 1427-1429
DOI
|
30 |
Smith, M. A., Harris, P. L., Sayre, L. M., and Perry, G. (1997) Iron accumulation in Alzheimer disease is a source of redoxgenerated free radicals. Proc. Natl. Acad. Sci. USA 94, 9866-9868
|
31 |
Sen, C. K., Khanna, S., Venojarvi, M., Trikha, P., Ellison, E. C., et al. (2002) Copper-induced vascular endothelial growth factor expression and wound healing. Am. J. Physiol. Heart Circ. Physiol. 282, H1821-1827
|
32 |
Huang, X., Atwood, C. S., Hartshorn, M. A., Multhaup, G., Goldstein, L. E., et al. (1999a) The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 38, 7609-7616
DOI
ScienceOn
|
33 |
Chua, C. C., Hamdy, R. C., and Chua, B. H. (1998) Upregulation of vascular endothelial growth factor by H2O2 in rat heart endothelial cells. Free Radic. Biol. Med. 25, 891-897
DOI
ScienceOn
|
34 |
Murata, M., Yudoh, K., Nakamura, H., Kato, T., Inoue, K., et al. (2006) Distinct signaling pathways are involved in hypoxiaand IL-1-induced VEGF expression in human articular chondrocytes. J. Orthop. Res. 24, 1544-1554
DOI
ScienceOn
|
35 |
Atwood, C. S., Scarpa, R. C., Huang, X., Moir, R. D., Jones, W. D., et al. (2000) Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42. J. Neurochem. 75, 1219-1233
DOI
ScienceOn
|
36 |
Hyman, B. T., Marzloff, K., and Arriagada, P. V. (1993) The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution. J. Neuropathol. Exp. Neurol. 52, 594-600
DOI
ScienceOn
|
37 |
Opazo, C., Barria, M. I., Ruiz, F. H., and Inestrosa, N. C. (2003) Copper reduction by copper binding proteins and its relation to neurodegenerative diseases. Biometals 16, 91-98
DOI
ScienceOn
|
38 |
Selkoe, D. J. (1991) The molecular pathology of Alzheimer's disease. Neuron 6, 487-498
DOI
ScienceOn
|