Kinetics of Binding of LPS to Recombinant CD14, TLR4, and MD-2 Proteins |
Shin, Han Jae
(Department of Biochemistry, Chungnam National University)
Lee, Hayyoung (Institute of Biotechnology, Chungnam National University) Park, Jong Dae (KT&G Central Research Institute) Hyun, Hak Chul (Department of Biochemistry, Chungnam National University) Sohn, Hyung Ok (KT&G Central Research Institute) Lee, Dong Wook (KT&G Central Research Institute) Kim, Young Sang (Department of Biochemistry, Chungnam National University) |
1 | Frey, E. A., Miller, D. S., Jahr, T. G., Sundan, A., Bazil, V., et al. (1992) Soluble CD14 participates in the response of cells to lipopolysaccharide. J. Exp. Med. 176, 1665-1671 DOI ScienceOn |
2 | Poltorak, A., He, X., Smirnova, I., Liu, M. Y., Van Huffel, C., et al. (1998) Defective LPS signaling in C3H/HeJ and C57BL/ 10ScCr mice: mutations in Tlr4 gene. Science 282, 2085-2088 DOI ScienceOn |
3 | Saitoh, S., Akashi, S., Yamada, T., Tanimura, N., Kobayashi, M., et al. (2004) Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization. Int. Immunol. 16, 961-969 DOI |
4 | Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., et al. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11, 443-451 DOI ScienceOn |
5 | Tobias, P. S., Soldau, K., Gegner, J. A., Mintz, D., and Ulevitch, R. J. (1995) Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J. Biol. Chem. 270, 10482-10488 DOI ScienceOn |
6 | Vales-Gomez, M., Reyburn, H. T., Mandelboim, M., and Strominger, J. L. (1998) Kinetics of interaction of HLA-C ligands with natural killer cell inhibitory receptors. Immunity 9, 337-344 DOI ScienceOn |
7 | Viriyakosol, S., Mathison, J. C., Tobias, P. S., and Kirkland, T. N. (2000) Structure-function analysis of CD14 as a soluble receptor for lipopolysaccharide. J. Biol. Chem. 275, 3144-3149 DOI ScienceOn |
8 | Nagai, Y., Akashi, S., Nagafuku, M., Ogata, M., Iwakura, Y., et al. (2002) Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat. Immunol. 3, 667-672 DOI |
9 | Visintin, A., Mazzoni, A., Spitzer, J. A., and Segal, D. M. (2001) Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4. Proc. Natl. Acad. Sci. USA 98, 12156-12161 |
10 | Wright, S. D., Ramos, R. A., Tobias, P. S., Ulevitch, R. J., and Mathison, J. C. (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249, 1431-1433 DOI |
11 | Hailman, E., Lichenstein, H. S., Wurfel, M. M., Miller, D. S., Johnson, D. A., et al. (1994) Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14. J. Exp. Med. 179, 269-277 DOI ScienceOn |
12 | Haziot, A., Rong, G. W., Bazil, V., Silver, J., and Goyert, S. M. (1994) Recombinant soluble CD14 inhibits LPS-induced tumor necrosis factor-alpha production by cells in whole blood. J. Immunol. 152, 5868-5876 |
13 | Lee, J. Y. and Hwang, D. H. (2006) The modulation of inflammatory gene expression by lipids: mediation through Toll-like receptors. Mol. Cells 21, 174-185 |
14 | Pugin, J., Heumann, I. D., Tomasz, A., Kravchenko, V. V., Akamatsu, Y., et al. (1994) CD14 is a pattern recognition receptor. Immunity 1, 509-516 DOI ScienceOn |
15 | Corr, M., Slanetz, A. E., Boyd, L. F., Jelonek, M. T., Khilko, S., et al. (1994) T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity. Science 265, 946-949 DOI |
16 | Re, F. and Strominger, J. L. (2002) Monomeric recombinant MD-2 binds toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness. J. Biol. Chem. 277, 23427-23432 DOI ScienceOn |
17 | Visintin, A., Halmen, K. A., Latz, E., Monks, B. G., and Golenbock, D. T. (2005) Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2. J. Immunol. 175, 6465-6472 DOI |
18 | Pugin, J., Schurer-Maly, C. C., Leturcq, D., Moriarty, A., Ulevitch, R. J., et al. (1993) Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide- binding protein and soluble CD14. Proc. Natl. Acad. Sci. USA 90, 2744-2748 |
19 | Thomas, C. J., Kapoor, M., Sharma, S., Bausinger, H., Zyilan, U., et al. (2002) Evidence of a trimolecular complex involving LPS, LPS binding protein and soluble CD14 as an effector of LPS response. FEBS Lett. 531, 184-188 DOI ScienceOn |
20 | Shimazu, R., Akashi, S., Ogata, H., Nagai, Y., Fukudome, K., et al. (1999) MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189, 1777-1782 DOI ScienceOn |
21 | Janeway, C. A., Jr. (1989) Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54 Pt 1, 1-13 |
22 | Koraha, J., Tsuneyoshi, N., Kimoto, M., Gauchat, J. F., Nakatake, H., et al. (2005) Comparison of lipopolysaccharide-binding functions of CD14 and MD-2. Clin. Diagn. Lab. Immunol. 12, 1292-1297 |
23 | da Silva Correia, J., Soldau, K., Christen, U., Tobias, P. S., and Ulevitch, R. J. (2001) Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2. J. Biol. Chem. 276, 21129-21135 DOI ScienceOn |
24 | Medzhitov, R., Preston-Hurlburt, P., and Janeway, C. A., Jr. (1997) A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388, 394- 397 DOI ScienceOn |
25 | Kirkland, T. N., Finley, F., Leturcq, D., Moriarty, A., Lee, J. D., et al. (1993) Analysis of lipopolysaccharide binding by CD14. J. Biol. Chem. 268, 24818-24823 |
26 | Poltorak, A., Ricciardi-Castagnoli, P., Citterio, S., and Beutler, B. (2000) Physical contact between lipopolysaccharide and tolllike receptor 4 revealed by genetic complementation. Proc. Natl. Acad. Sci. USA 97, 2163-2167 |
27 | Viriyakosol, S., Tobias, P. S., Kitchens, R. L., and Kirkland, T. N. (2001) MD-2 binds to bacterial lipopolysaccharide. J. Biol. Chem. 276, 38044-38051 |
28 | Kim, J. I., Lee, C. J., Jin, M. S., Lee, C. H., Paik, S. G., et al. (2005) Crystal structure of CD14 and its implications for lipopolysaccharide signaling. J. Biol. Chem. 280, 11347-11351 DOI ScienceOn |
29 | Rothbard, J. B. and Gefter, M. L. (1991) Interactions between immunogenic peptides and MHC proteins. Annu. Rev. Immunol. 9, 527-565 DOI ScienceOn |
30 | Moore, R. A., Bates, N. C., and Hancock, R. E. (1986) Interaction of polycationic antibiotics with Pseudomonas aeruginosa lipopolysaccharide and lipid A studied by using dansylpolymyxin. Antimicrob. Agents Chemother. 29, 496-500 DOI ScienceOn |
31 | Hyakushima, N., Mitsuzawa, H., Nishitani, C., Sano, H., Kuronuma, K., et al. (2004) Interaction of soluble form of recombinant extracellular TLR4 domain with MD-2 enables lipopolysaccharide binding and attenuates TLR4-mediated signaling. J. Immunol. 173, 6949-6954 DOI |
32 | Qureshi, S. T., Lariviere, L., Leveque, G., Clermont, S., Moore, K. J., et al. (1999) Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 189, 615-625 DOI ScienceOn |
33 | Akashi, S., Saitoh, S., Wakabayashi, Y., Kikuchi, T., Takamura, N., et al. (2003) Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14. J. Exp. Med. 198, 1035-1042 DOI ScienceOn |
34 | Bell, J. K., Mullen, G. E., Leifer, C. A., Mazzoni, A., Davies, D. R., et al. (2003) Leucine-rich repeats and pathogen recognition in Toll-like receptors. Trends Immunol. 24, 528-533 DOI ScienceOn |