A Helix-induced Oligomeric Transition of Gaegurin 4, an Antimicrobial Peptide Isolated from a Korean Frog |
Eun, Su-Yong
(Department of Physiology, College of Medicine, Cheju National University)
Jang, Hae-Kyung (Department of Chemistry, Mokpo National University) Han, Seong-Kyu (College of Veterinary Medicine, Seoul National University) Ryu, Pan-Dong (College of Veterinary Medicine, Seoul National University) Lee, Byeong-Jae (Laboratory of Molecular Genetics, Institute of Molecular Biology and Genetics, School of Biological Sciences, Seoul National University) Han, Kyou-Hoon (Korea Research Institute of Bioscience and Biotechnology) Kim, Soon-Jong (Department of Chemistry, Mokpo National University) |
1 | He, K., Ludtke, S. J., Worcester, D. L., and Huang, H. W. (1996) Neutron scattering in the plane of membranes: structure of alamethicin pores. Biophys. J. 70, 2659-2666 DOI ScienceOn |
2 | Hong, D., Hoshino, M., Kuboi, R., and Goto, Y. (1999) Clustering of fluorine-fubstituted alcohols as a factor responsible for their marked effects on proteins and peptides. J. Am. Chem. Soc. 121, 8427-8433 DOI ScienceOn |
3 | Kim, H. J., Kim, S. S., Lee, M. H., Lee, B. J., and Ryu, P. D. (2004) Role of C-terminal heptapeptide in pore-forming activity of antimicrobial agent, gaegurin 4. J. Pept. Res. 64, 151-158 DOI ScienceOn |
4 | Kim, S., Kim, S. S., Bang, Y. J., Kim, S. J., and Lee, B. J. (2003) In vitro activities of native and designed peptide antibiotics against drug sensitive and resistant tumor cell lines. Peptides 24, 945-953 DOI ScienceOn |
5 | Matsuzaki, K., Murase, O., Fujii, N., and Miyajima, K. (1996) An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation. Biochemistry 35, 11361-11368 DOI ScienceOn |
6 | Park, S. H., Kim, Y. K., Park, J. W., Lee, B., and Lee, B. J. (2000) Solution structure of the antimicrobial peptide gaegurin 4 by H and 15N nuclear magnetic resonance spectroscopy. Eur. J. Biochem. 267, 2695-2704 DOI ScienceOn |
7 | Yang, L., Harroun, T. A., Weiss, T. M., Ding, L., and Huang, H. W. (2001) Barrel-stave model or toroidal model? A case study on melittin pores. Biophys. J. 81, 1475-1485 DOI ScienceOn |
8 | Kumaran, S. and Roy, R. P. (1999) Helix-enhancing propensity of fluoro and alkyl alcohols: influence of pH, temperature and cosolvent concentration on the helical conformation of peptides. J. Pept. Res. 53, 284-293 DOI ScienceOn |
9 | Marianayagam, N. J., Sunde, M., and Matthews, J. M. (2004) The power of two: protein dimerization in biology. Trends Biochem. Sci. 29, 618-625 DOI |
10 | Lebowitz, J., Lewis, M. S., and Schuck, P. (2002) Modern analytical ultracentrifugation in protein science: a tutorial review. Protein Sci. 11, 2067-2079 DOI ScienceOn |
11 | Kim, H. J., Han, S. K., Park, J. B., Baek, H. J., Lee, B. J., et al. (1999a) Gaegurin 4, a peptide antibiotic of frog skin, forms voltage-dependent channels in planar lipid bilayers. J. Pept. Res. 53, 1-7 DOI ScienceOn |
12 | Suh, J. Y., Lee, K. H., Chi, S. W., Hong, S. Y., Choi, B. W., et al. (1996) Unusually stable helical kink in the antimicrobial peptide-a derivative of gaegurin. FEBS Lett. 392, 309-312 DOI ScienceOn |
13 | Park, S. H., Kim, H. E., Kim, C. M., Yun, H. J., Choi, E. C., et al. (2002) Role of proline, cysteine and a disulphide bridge in the structure and activity of the anti-microbial peptide gaegurin 5. Biochem. J. 368, 171-182 DOI ScienceOn |
14 | Scholtz, J. M., Qian, H., York, E. J., Stewart, J. M., and Baldwin, R. L. (1991) Parameters of helix-coil transition theory for alanine-based peptides of varying chain lengths in water. Biopolymers 31, 1463-1470 DOI ScienceOn |
15 | Yoshida, K., Yamaguchi, T., Adachi, T., Otomo, T., Matsuo, D., et al. (2003) Structure and dynamics of hexafluoroisopropanol- water mixtures by X-ray diffraction, small-angle neutron scattering, NMR spectroscopy, and mass spectrometry. J. Chem. Phys. 119, 6131-6142 |
16 | Matsuzaki, K., Murase, O., Fujii, N., and Miyajima, K. (1995) Translocation of a channel-forming antimicrobial peptide, magainin 2, across lipid bilayers by forming a pore. Biochemistry 34, 6521-6526 DOI ScienceOn |
17 | Kahn, F., Kahn, R. H., and Muzammil, S. (2000) Alcoholinduced versus anion-induced states of alpha-chymotrypsinogen. A at low pH. Biochim. Biophys. Acta 1481, 229-236 DOI ScienceOn |
18 | Cruciani, R. A., Barker, J. L., Durell, S. R., Raghunathan, G., Zasloff, H. R. M., et al. (1992) Magainin 2, a natural antibiotic from frog skin, forms ion channels in lipid bilayer membranes. Eur. J. Pharmacol. 226, 287-296 DOI ScienceOn |
19 | Lau, S. Y., Taneja, A. K., and Hodges, R. S. (1984) Synthesis of a model protein of defined secondary and quaternary structure. Effect of chain length on the stabilization and formation of two-stranded alpha-helical coiled-coils. J. Biol. Chem. 259, 13253-13261 |
20 | Villarroel, A., Burnashev, N., and Sakmann, B. (1995) Dimensions of the narrow portion of a recombinant NMDA receptor channel. Biophys. J. 68, 866-875 DOI ScienceOn |
21 | Rinaldi, A. C. (2002) Antimicrobial peptides from amphibian skin: an expanding scenario. Curr. Opin. Chem. Biol. 6, 799-804 DOI ScienceOn |
22 | Yang, L., Weiss, T. M., Lehrer, R. I., and Huang, H. W. (2000) Crystallization of antimicrobial pores in membranes: magainin and protegrin. Biophys. J. 79, 2002-2009 DOI ScienceOn |
23 | Feder, R., Dagan, A., and Mor, A. (2000) Structural requirements for potent versus selective cytotoxicity for antimicrobial dermaseptin S4 derivatives. J. Biol. Chem. 277, 16941-16951 |
24 | Roccatano, D., Fioroni, M., Zacharias, M., and Colombo, G. (2005) Effect of hexafluoroisopropanol alcohol on the structure of melittin: A molecular dynamics simulation study. Protein Sci. 14, 2582-2589 DOI ScienceOn |
25 | Knott, G. D. (1979) MLAB-a mathematical modeling tool, Comput. Programs Biomed. 10, 271-280 DOI ScienceOn |
26 | Coronado, R. and Latorre, R. (1983) Phospholipid bilayers made from monolayers on patch-clamp pipettes. Biophys. J. 43, 231-236 DOI ScienceOn |
27 | Hirota, N., Mizuno, K., and Goto, Y. (1997) Cooperative alphahelix formation of beta-lactoglobulin and melittin induced by hexafluoroisopropanol. Protein Sci. 6, 416-421 DOI ScienceOn |
28 | Kim, S. H., Kim, J. Y., Lee, B. J., and Kim, S. J. (1999b) Synthesis and characterization of GGN4 and its tryptophan substituted analogue peptides. J. Biochem. Mol. Biol. 32, 12-19 |
29 | Boman, H. G. (1995) Peptide antibiotics and their role in innate immunity. Annu. Rev. Immunol. 13, 61-92 DOI ScienceOn |
30 | Park, J. M., Jung, J. E., and Lee, B. J. (1994) Antimicrobial peptides from the skin of a Korean frog, Rana rugos. Biochem. Biophys. Res. Commun. 205, 948-954 DOI ScienceOn |
31 | Zasloff, M. (2002) Antimicrobial peptides of multicellular organisms. Nature 415, 389-395 DOI ScienceOn |
32 | Mazzuca, C., Venanzi, M., Formaggio, F., Toniolo, C., and Pispisa, B. (2005) Mechanism of membrane activity of the antibiotic trichogin GA IV: a two-state transition controlled by peptide concentration. Biophys. J. 88, 3411-3421 DOI ScienceOn |
33 | Stewart, J. M. (1993) in The Amphipathic Helix, Epand, R. M. (ed.), CRC Press, Boca Raton, Fl. 21-37 |
34 | Fleming, K. G., Ackerman, A. L., and Engelman, D. M. (1997) The effect of point mutations on the free energy of transmembrane alpha-helix dimerization. J. Mol. Biol. 272, 266-275 DOI ScienceOn |
35 | Mchaourab, H. S., Hyde, J. S., and Feix, J. B. (1993) Aggregation state of spin-labeled cecropin AD in solution. Biochemistry 32, 11895-11902 DOI ScienceOn |