1 |
Silhavy, D., Molnar, A., Lucioli, A., Szittya, G., Hornyik, C., et al. (2002) A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide doublestranded RNAs. EMBO J. 21, 3070-3080
DOI
ScienceOn
|
2 |
Slack, F. J., Basson, M., Liu, Z., Ambros, V., Horvitz, H. R., et al. (2000) The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol. Cell 5, 659-669
DOI
ScienceOn
|
3 |
Song, J. J., Liu, J., Tolia, N. H., Schneiderman, J., Smith, S. K., et al. (2003) The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat. Struct. Biol. 10, 1026-1032
DOI
ScienceOn
|
4 |
Sunkar, R. and Zhu, J. K. (2004) Novel and stress-regulated microRNAs and other small RNAs from Arabidopsis. Plant Cell 16, 2001-2019
DOI
ScienceOn
|
5 |
Tomari, Y., Du, T., Haley, B., Schwarz, D. S., Bennett, R., et al. (2004a) RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 116, 831-841
DOI
ScienceOn
|
6 |
Vazquez, F., Gasciolli, V., Crete, P., and Vaucheret, H. (2004a) The nuclear dsRNA binding protein HYL1 is required for microRNA accumulation and plant development, but not posttranscriptional transgene silencing. Curr. Biol. 14, 346-351
DOI
ScienceOn
|
7 |
Wianny, F. and Zernicka-Goetz, M. (2000) Specific interference with gene function by double-stranded RNA in early mouse development. Nat. Cell. Biol. 2, 70-75
DOI
ScienceOn
|
8 |
Zeng, Y., Wagner, E. J., and Cullen, B. R. (2002) Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 9, 1327-1333
DOI
ScienceOn
|
9 |
Ambros, V. (2004) The functions of animal microRNAs. Nature 431, 350-.355
DOI
ScienceOn
|
10 |
Ambros, V., Bartel, B., Bartel, D. P., Burge, C. B., Carrington, J. C., et al. (2003a) A uniform system for microRNA annotation. RNA 9, 277-.279
|
11 |
Ambros, V., Lee, R. C., Lavanway, A., Williams, P. T., and Jewell, D. (2003b) MicroRNAs and other tiny endogenous RNAs in C. elegans. Curr. Biol. 13, 807-.818
DOI
ScienceOn
|
12 |
Calin, G. A., Liu, C. G., Sevignani, C., Ferracin, M., Felli, N., et al. (2004) MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl. Acad. Sci. USA 101, 11755-.11760
|
13 |
Denli, A. M., Tops, B. B., Plasterk, R. H., Ketting, R. F., and Hannon, G. J. (2004) Processing of primary microRNAs by the Microprocessor complex. Nature 432, 231-.235
DOI
ScienceOn
|
14 |
Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., et al. (2001a) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-.498
DOI
ScienceOn
|
15 |
Elbashir, S. M., Harborth, J., Weber, K., and Tuschl, T. (2002) Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26, 199-.213
DOI
ScienceOn
|
16 |
Fagard, M., Boutet, S., Morel, J. B., Bellini, C., and Vaucheret, H. (2000) AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals. Proc. Natl. Acad. Sci. USA 97, 11650-.11654
|
17 |
Khvorova, A., Reynolds, A., and Jayasena, S. D. (2003) Functional siRNAs and miRNAs exhibit strand bias. Cell 115, 209-.216
DOI
ScienceOn
|
18 |
Griffiths-Jones, S. (2004) The microRNA Registry. Nucleic Acids Res. 32, D109-.111
|
19 |
Hutvagner, G., McLachlan, J., Pasquinelli, A. E., Balint, E., Tuschl, T., et al. (2001) A cellular function for the RNAinterference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-.838
DOI
ScienceOn
|
20 |
Ketting, R. F. and Plasterk, R. H. (2004) What''s new about RNAi? Meeting on siRNAs and miRNAs. EMBO Rep. 5, 762-.765
DOI
ScienceOn
|
21 |
Knight, S. W. and Bass, B. L. (2001) A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293, 2269-.2271
DOI
ScienceOn
|
22 |
Kuwabara, T., Hsieh, J., Nakashima, K., Taira, K., and Gage, F. H. (2004) A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell 116, 779-.793
DOI
ScienceOn
|
23 |
Lee, Y., Ahn, C., Han, J., Choi, H., Kim, J., et al. (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-.419
DOI
ScienceOn
|
24 |
Lee, Y. S., Nakahara, K., Pham, J. W., Kim, K., He, Z., et al. (2004b) Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117, 69-.81
DOI
ScienceOn
|
25 |
Liu, J., Carmell, M. A., Rivas, F. V., Marsden, C. G., Thomson, J. M., et al. (2004a) Argonaute2 is the catalytic engine of mammalian RNAi. Science 305, 1437-1441
DOI
ScienceOn
|
26 |
Llave, C., Xie, Z., Kasschau, K. D., and Carrington, J. C. (2002b) Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA. Science 297, 2053-2056
DOI
ScienceOn
|
27 |
Morris, K. V., Chan, S. W., Jacobsen, S. E., and Looney, D. J. (2004) Small interfering RNA-induced transcriptional gene silencing in human cells. Science 305, 1289-1292
DOI
ScienceOn
|
28 |
Ma, J. B., Ye, K., and Patel, D. J. (2004) Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 429, 318-322
DOI
ScienceOn
|
29 |
Meister, G. and Tuschl, T. (2004) Mechanisms of gene silencing by double-stranded RNA. Nature 431, 343-349
DOI
ScienceOn
|
30 |
Meyer, E. and Garnier, O. (2002) Non-Mendelian inheritance and homology-dependent effects in ciliates. Adv. Genet. 46, 305-337
DOI
|
31 |
Murchison, E. P. and Hannon, G. J. (2004) miRNAs on the move: miRNA biogenesis and the RNAi machinery. Curr. Opin. Cell. Biol. 16, 223-229
DOI
ScienceOn
|
32 |
Pal-Bhadra, M., Leibovitch, B. A., Gandhi, S. G., Rao, M., Bhadra, U., et al. (2004) Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi ma14 Small RNAs: Classification, Biogenesis, and Function chinery. Science 303, 669-672
DOI
ScienceOn
|
33 |
Peragine, A., Yoshikawa, M., Wu, G., Albrecht, H. L., and Poethig, R. S. (2004) SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of transacting siRNAs in Arabidopsis. Genes Dev. 18, 2368-2379
DOI
ScienceOn
|
34 |
Reinhart, B. J. and Bartel, D. P. (2002) Small RNAs correspond to centromere heterochromatic repeats. Science 297, 1831
DOI
ScienceOn
|
35 |
Reinhart, B. J., Weinstein, E. G., Rhoades, M. W., Bartel, B., and Bartel, D. P. (2002) MicroRNAs in plants. Genes Dev. 16, 1616-1626
DOI
ScienceOn
|
36 |
Metzler, M., Wilda, M., Busch, K., Viehmann, S., and Borkhardt, A. (2004) High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes Cancer 39, 167-169
DOI
ScienceOn
|
37 |
Hamilton, A., Voinnet, O., Chappell, L., and Baulcombe, D. (2002) Two classes of short interfering RNA in RNA silencing. EMBO J. 21, 4671-.4679
DOI
ScienceOn
|
38 |
Ishizuka, A., Siomi, M. C., and Siomi, H. (2002) A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev. 16, 2497-.2508
DOI
ScienceOn
|
39 |
Ketting, R. F., Haverkamp, T. H., van Luenen, H. G., and Plasterk, R. H. (1999) Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell 99, 133-.141
DOI
ScienceOn
|
40 |
Lingel, A., Simon, B., Izaurralde, E., and Sattler, M. (2004) Nucleic acid 3′-end recognition by the Argonaute2 PAZ domain. Nat. Struct. Mol. Biol. 11, 576-577
DOI
ScienceOn
|
41 |
Ye, K., Malinina, L., and Patel, D. J. (2003) Recognition of small interfering RNA by a viral suppressor of RNA silencing. Nature 426, 874-878
DOI
ScienceOn
|
42 |
Houbaviy, H. B., Murray, M. F., and Sharp, P. A. (2003) Embryonic stem cell-specific MicroRNAs. Dev. Cell. 5, 351-.358
DOI
ScienceOn
|
43 |
Chen, C. Z., Li, L., Lodish, H. F., and Bartel, D. P. (2004) MicroRNAs modulate hematopoietic lineage differentiation. Science 303, 83-.86
DOI
ScienceOn
|
44 |
Hall, I. M., Shankaranarayana, G. D., Noma, K., Ayoub, N., Cohen, A., et al. (2002) Establishment and maintenance of a heterochromatin domain. Science 297, 2232-.2237
DOI
ScienceOn
|
45 |
Mochizuki, K. and Gorovsky, M. A. (2004b) Small RNAs in genome rearrangement in Tetrahymena. Curr. Opin. Genet. Dev. 14, 181-187
DOI
ScienceOn
|
46 |
Okamura, K., Ishizuka, A., Siomi, H., and Siomi, M. C. (2004) Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev. 18, 1655-1666
DOI
ScienceOn
|
47 |
Suh, M. R., Lee, Y., Kim, J. Y., Kim, S. K., Moon, S. H., et al. (2004) Human embryonic stem cells express a unique set of microRNAs. Dev. Biol. 270, 488-498
DOI
ScienceOn
|
48 |
Bernstein, E., Caudy, A. A., Hammond, S. M., and Hannon, G. J. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363-.366
DOI
ScienceOn
|
49 |
Caplen, N. J., Parrish, S., Imani, F., Fire, A., and Morgan, R. A. (2001) Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. USA 98, 9742-.9747
|
50 |
Kurihara, Y. and Watanabe, Y. (2004) Arabidopsis micro-RNA biogenesis through Dicer-like 1 protein functions. Proc. Natl. Acad. Sci. USA 101, 12753-.12758
|
51 |
Lagos-Quintana, M., Rauhut, R., Lendeckel, W., and Tuschl, T. (2001) Identification of novel genes coding for small expressed RNAs. Science 294, 853-.858
DOI
ScienceOn
|
52 |
Matzke, M. A. and Birchler, J. A. (2005) RNAi-mediated pathways in the nucleus. Nat. Rev. Genet. 6, 24-35
DOI
ScienceOn
|
53 |
Tomari, Y., Matranga, C., Haley, B., Martinez, N., and Zamore, P. D. (2004b) A protein sensor for siRNA asymmetry. Science 306, 1377-1380
DOI
ScienceOn
|
54 |
Vargason, J. M., Szittya, G., Burgyan, J., and Tanaka Hall, T. M. (2003) Size selective recognition of siRNA by an RNA silencing suppressor. Cell 115, 799-811
DOI
ScienceOn
|
55 |
Park, W., Li, J., Song, R., Messing, J., and Chen, X. (2002) CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana. Curr. Biol. 12, 1484-1495
DOI
ScienceOn
|
56 |
Ketting, R. F., Fischer, S. E., Bernstein, E., Sijen, T., Hannon, G. J., et al. (2001) Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15, 2654-.2659
DOI
ScienceOn
|
57 |
Landthaler, M., Yalcin, A., and Tuschl, T. (2004) The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Curr. Biol. 14, 2162-.2167
DOI
ScienceOn
|
58 |
Lee, R. C. and Ambros, V. (2001) An extensive class of small RNAs in Caenorhabditis elegans. Science 294, 862-.864
DOI
ScienceOn
|
59 |
Lee, Y., Kim, M., Han, J., Yeom, K. H., Lee, S., et al. (2004a) V. Narry Kim 13 MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23, 4051-.4060
DOI
ScienceOn
|
60 |
Mochizuki, K., Fine, N. A., Fujisawa, T., and Gorovsky, M. A. (2002) Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena. Cell 110, 689-699
DOI
ScienceOn
|
61 |
Liu, Y., Mochizuki, K., and Gorovsky, M. A. (2004b) Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena. Proc. Natl. Acad. Sci. USA 101, 1679-1684
|
62 |
Djikeng, A., Shi, H., Tschudi, C., and Ullu, E. (2001) RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposon-derived 24-26-nucleotide RNAs. RNA 7, 1522-.1530
|
63 |
Grishok, A., Pasquinelli, A. E., Conte, D., Li, N., Parrish, S., et al. (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106, 23-.34
DOI
ScienceOn
|
64 |
Schwarz, D. S., Hutvagner, G., Du, T., Xu, Z., Aronin, N., et al. (2003) Asymmetry in the assembly of the RNAi enzyme complex. Cell 115, 199-208
DOI
ScienceOn
|
65 |
van der Krol, A. R., Mur, L. A., Beld, M., Mol, J. N., and Stuitje, A.R. (1990) Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression. Plant Cell 2, 291-299
DOI
|
66 |
Aukerman, M. J. and Sakai, H. (2003) Regulation of flowering time and floral organ identity by a microRNA and its APETALA2-like target genes. Plant Cell 15, 2730-.2741
DOI
ScienceOn
|
67 |
Bartel, D. P. and Chen, C. Z. (2004) Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet. 5, 396-.400
|
68 |
Bohnsack, M. T., Czaplinski, K., and Gorlich, D. (2004) Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10, 185-.191
DOI
|
69 |
Herr, A. J., Jensen, M. B., Dalmay, T., and Baulcombe, D. C. (2005) RNA Polymerase IV Directs Silencing of Endogenous DNA. Science Feb 3; [Epub ahead of print]
|
70 |
Han, M. H., Goud, S., Song, L., and Fedoroff, N. (2004b) The Arabidopsis double-stranded RNA-binding protein HYL1 plays a role in microRNA-mediated gene regulation. Proc. Natl. Acad. Sci. USA 101, 1093-.1098
|
71 |
Lau, N. C., Lim, L. P., Weinstein, E. G., and Bartel, D. P. (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294, 858-.862
DOI
ScienceOn
|
72 |
Reinhart, B. J., Slack, F. J., Basson, M., Pasquinelli, A. E., Bettinger, J. C., et al. (2000) The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403, 901-906
DOI
ScienceOn
|
73 |
Yi, R., Qin, Y., Macara, I. G., and Cullen, B. R. (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17, 3011-3016
DOI
ScienceOn
|
74 |
Yang, S., Tutton, S., Pierce, E., and Yoon, K. (2001) Specific V. Narry Kim 15 double-stranded RNA interference in undifferentiated mouse embryonic stem cells. Mol. Cell. Biol. 21, 7807-7816
DOI
ScienceOn
|
75 |
Aravin, A. A., Naumova, N. M., Tulin, A. V., Vagin, V. V., Rozovsky, Y. M. et al. (2001) Double-stranded RNAmediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline. Curr. Biol 11, 1017-.1027
DOI
ScienceOn
|
76 |
Gregory, R. I., Yan, K. P., Amuthan, G., Chendrimada, T., Doratotaj, B., et al. (2004) The microprocessor complex mediates the genesis of microRNAs. Nature 432, 235-.240
DOI
ScienceOn
|
77 |
Liu, Q., Rand, T. A., Kalidas, S., Du, F., Kim, H. E., et al. (2003) R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301, 1921-1925
DOI
ScienceOn
|
78 |
Mette, M. F., van der Winden, J., Matzke, M., and Matzke, A. J. (2002) Short RNAs can identify new candidate transposable element families in Arabidopsis. Plant Physiol. 130, 6-9
DOI
ScienceOn
|
79 |
Volpe, T. A., Kidner, C., Hall, I. M., Teng, G., Grewal, S. I., et al. (2002) Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297, 1833-1837
DOI
ScienceOn
|
80 |
Chang, S., Johnston, R. J., Jr., Frokjaer-Jensen, C., Lockery, S., and Hobert, O. (2004) MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode. Nature 430, 785-.789
DOI
ScienceOn
|
81 |
Tam, W., Hughes, S. H., Hayward, W. S., and Besmer, P. (2002) Avian bic, a gene isolated from a common retroviral site in avian leukosis virus-induced lymphomas that encodes a noncoding RNA, cooperates with c-myc in lymphomagenesis and erythroleukemogenesis. J. Virol. 76, 4275-4286
DOI
|
82 |
Song, J. J., Smith, S. K., Hannon, G. J., and Joshua-Tor, L. (2004) Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305, 1434-1437
DOI
ScienceOn
|
83 |
Yu, B., Yang, Z., Li, J., Minakhina, S., Yang, M., et al. (2005) Methylation as a crucial step in plant microRNA biogenesis. Science 307, 932-935
DOI
ScienceOn
|
84 |
Aravin, A. A., Klenov, M. S., Vagin, V. V., Bantignies, F., Cavalli, G., et al. (2004) Dissection of a natural RNA silencing process in the Drosophila melanogaster germ line. Mol. Cell. Biol. 24, 6742-.6750
DOI
ScienceOn
|
85 |
Elbashir, S. M., Martinez, J., Patkaniowska, A., Lendeckel, W., and Tuschl, T. (2001b) Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20, 6877-.6888
DOI
ScienceOn
|
86 |
Llave, C., Kasschau, K. D., Rector, M. A., and Carrington, J. C. (2002a) Endogenous and silencing-associated small RNAs in plants. Plant Cell 14, 1605-1619
DOI
|
87 |
Olsen, P. H. and Ambros, V. (1999) The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev. Biol. 216, 671-680
DOI
ScienceOn
|
88 |
Tabara, H., Sarkissian, M., Kelly, W. G., Fleenor, J., Grishok, A., et al. (1999) The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99, 123-132
DOI
ScienceOn
|
89 |
Tam, W. (2001) Identification and characterization of human BIC, a gene on chromosome 21 that encodes a noncoding RNA. Gene 274, 157-167
DOI
ScienceOn
|
90 |
Chen, X. (2004) A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development. Science 303, 2022-.2025
DOI
ScienceOn
|
91 |
Pfeffer, S., Zavolan, M., Grasser, F. A., Chien, M., Russo, J. J., et al. (2004) Identification of virus-encoded microRNAs. Science, 304, 734-736
DOI
ScienceOn
|
92 |
Mourrain, P., Beclin, C., Elmayan, T., Feuerbach, F., Godon, C., et al. (2000) Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance. Cell 101, 533-542
DOI
ScienceOn
|
93 |
Lee, R. C., Feinbaum, R. L., and Ambros, V. (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-.854
DOI
ScienceOn
|
94 |
Noma, K., Sugiyama, T., Cam, H., Verdel, A., Zofall, M., et al. (2004) RITS acts in cis to promote RNA interferencemediated transcriptional and post-transcriptional silencing. Nat. Genet. 36, 1174-1180
DOI
ScienceOn
|
95 |
Pal-Bhadra, M., Bhadra, U., and Birchler, J. A. (2002) RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila. Mol. Cell 9, 315-327
DOI
ScienceOn
|
96 |
Xie, Z., Johansen, L. K., Gustafson, A. M., Kasschau, K. D., Lellis, A. D., et al. (2004) Genetic and functional diversification of small RNA pathways in plants. PLoS Biol. 2, E104
DOI
ScienceOn
|
97 |
Baulcombe, D. (2004) RNA silencing in plants. Nature 431, 356-.363
DOI
ScienceOn
|
98 |
Kumar, M. and Carmichael, G. G. (1998) Antisense RNA: function and fate of duplex RNA in cells of higher eukaryotes. Microbiol. Mol. Biol. Rev. 62, 1415-.1434
|
99 |
Mourelatos, Z., Dostie, J., Paushkin, S., Sharma, A., Charroux, B., et al. (2002) miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 16, 720-728
DOI
ScienceOn
|
100 |
Telfer, A. and Poethig, R. S. (1998) HASTY: a gene that regulates the timing of shoot maturation in Arabidopsis thaliana. Development 125, 1889-1898
|
101 |
Lecellier, C. H. and Voinnet, O. (2004) RNA silencing: no mercy for viruses? Immunol. Rev. 198, 285-.303
DOI
ScienceOn
|
102 |
Bollman, K. M., Aukerman, M. J., Park, M. Y., Hunter, C., Berardini, T. Z., et al. (2003) HASTY, the Arabidopsis ortholog of exportin 5/MSN5, regulates phase change and morphogenesis. Development 130, 1493-.1504
DOI
ScienceOn
|
103 |
Boutet, S., Vazquez, F., Liu, J., Beclin, C., Fagard, M., et al. (2003) Arabidopsis HEN1. A Genetic Link between Endogenous miRNA Controlling Development and siRNA Controlling Transgene Silencing and Virus Resistance. Curr. Biol. 13, 843-.848
DOI
ScienceOn
|
104 |
Caudy, A.A., Myers, M., Hannon, G.J. and Hammond, S.M. (2002) Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev, 16, 2491-.2496
DOI
ScienceOn
|
105 |
Yan, K. S., Yan, S., Farooq, A., Han, A., Zeng, L., et al. (2003) Structure and conserved RNA binding of the PAZ domain. Nature 426, 468-474
DOI
ScienceOn
|
106 |
Lippman, Z. and Martienssen, R. (2004) The role of RNA interference in heterochromatic silencing. Nature 431, 364-370
DOI
ScienceOn
|
107 |
Mochizuki, K. and Gorovsky, M. A. (2004a) Conjugationspecific small RNAs in Tetrahymena have predicted properties of scan (scn) RNAs involved in genome rearrangement. Genes Dev. 18, 2068-2073
DOI
ScienceOn
|
108 |
Vastenhouw, N. L. and Plasterk, R. H. (2004) RNAi protects the Caenorhabditis elegans germline against transposition. Trends Genet. 20, 314-319
DOI
ScienceOn
|
109 |
Yekta, S., Shih, I. H., and Bartel, D. P. (2004) MicroRNAdirected cleavage of HOXB8 mRNA. Science 304, 594-596
DOI
ScienceOn
|
110 |
Aravin, A. A., Lagos-Quintana, M., Yalcin, A., Zavolan, M., Marks, D., et al. (2003) The small RNA profile during Drosophila melanogaster development. Dev. Cell. 5, 337-.350
DOI
ScienceOn
|
111 |
Cai, X., Hagedorn, C. H., and Cullen, B. R. (2004) Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10, 1957-. 1966
DOI
ScienceOn
|
112 |
Lewis, B. P., Burge, C. B., and Bartel, D. P. (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-.20
DOI
ScienceOn
|
113 |
Lund, E., Guttinger, S., Calado, A., Dahlberg, J. E., and Kutay, U. (2004) Nuclear export of microRNA precursors. Science 303, 95-98
DOI
ScienceOn
|
114 |
Moss, E. G., Lee, R. C., and Ambros, V. (1997) The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 88, 637-646
DOI
ScienceOn
|
115 |
Kawasaki, H. and Taira, K. (2004) Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature 431, 211-.217
DOI
ScienceOn
|
116 |
Napoli, C., Lemieux, C., and Jorgensen, R. (1990) Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 2, 279-289
DOI
ScienceOn
|
117 |
Schramke, V. and Allshire, R. (2003) Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing. Science 301, 1069-1074
DOI
ScienceOn
|
118 |
Baulcombe, D. C. and Molnar, A. (2004) Crystal structure of p19--a universal suppressor of RNA silencing. Trends Biochem. Sci. 29, 279-.281
DOI
ScienceOn
|
119 |
Gil, J. and Esteban, M. (2000) Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action. Apoptosis 5, 107-.114
DOI
ScienceOn
|
120 |
Han, J., Lee, Y., Yeom, K. H., Kim, Y. K., Jin, H., et al. (2004a) The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18, 3016-.3027
DOI
ScienceOn
|
121 |
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., et al. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-.811
DOI
ScienceOn
|
122 |
Bartel, D. P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-.297
DOI
ScienceOn
|
123 |
Lee, Y., Jeon, K., Lee, J. T., Kim, S., and Kim, V. N. (2002) MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 21, 4663-.4670
DOI
ScienceOn
|
124 |
Lippman, Z., Gendrel, A. V., Black, M., Vaughn, M. W., Dedhia, N., et al. (2004) Role of transposable elements in heterochromatin and epigenetic control. Nature 430, 471-476
DOI
ScienceOn
|
125 |
Verdel, A., Jia, S., Gerber, S., Sugiyama, T., Gygi, S., et al. (2004) RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303, 672-676
DOI
ScienceOn
|
126 |
Brennecke, J., Hipfner, D. R., Stark, A., Russell, R. B., and Cohen, S. M. (2003) bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113, 25-.36
DOI
ScienceOn
|
127 |
Chalker, D. L. and Yao, M. C. (2001) Nongenic, bidirectional transcription precedes and may promote developmental DNA deletion in Tetrahymena thermophila. Genes Dev. 15, 1287-.1298
DOI
ScienceOn
|
128 |
Chapman, E. J., Prokhnevsky, A. I., Gopinath, K., Dolja, V. V., and Carrington, J. C. (2004) Viral RNA silencing suppressors inhibit the microRNA pathway at an intermediate step. Genes Dev. 18, 1179-.1186
DOI
ScienceOn
|
129 |
Papp, I., Mette, M. F., Aufsatz, W., Daxinger, L., Schauer, S. E., et al. (2003) Evidence for nuclear processing of plant micro RNA and short interfering RNA precursors. Plant Physiol. 132, 1382-1390
DOI
|
130 |
Kennerdell, J. R. and Carthew, R. W. (1998) Use of dsRNAmediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell 95, 1017-.1026
DOI
ScienceOn
|
131 |
Wightman, B., Ha, I., and Ruvkun, G. (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin- 4 mediates temporal pattern formation in C. elegans. Cell 75, 855-862
DOI
ScienceOn
|
132 |
Lakatos, L., Szittya, G., Silhavy, D., and Burgyan, J. (2004) Molecular mechanism of RNA silencing suppression mediated by p19 protein of tombusviruses. EMBO J. 23, 876-.884
DOI
ScienceOn
|
133 |
Zilberman, D., Cao, X., and Jacobsen, S. E. (2003) ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science 299, 716-719
DOI
ScienceOn
|
134 |
Taverna, S. D., Coyne, R. S., and Allis, C. D. (2002) Methylation of histone h3 at lysine 9 targets programmed DNA elimination in tetrahymena. Cell 110, 701-711
DOI
ScienceOn
|
135 |
Zilberman, D., Cao, X., Johansen, L. K., Xie, Z., Carrington, J. C., et al. (2004) Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats. Curr. Biol. 14, 1214-1220
DOI
ScienceOn
|
136 |
Kennerdell, J. R., Yamaguchi, S., and Carthew, R. W. (2002) RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E. Genes Dev, 16, 1884-.1889
DOI
ScienceOn
|
137 |
Vazquez, F., Vaucheret, H., Rajagopalan, R., Lepers, C., Gasciolli, V., et al. (2004b) Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs. Mol. Cell 16, 69-79
DOI
ScienceOn
|
138 |
Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., et al. (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. USA 99, 15524-.15529
|
139 |
Chan, S. W., Zilberman, D., Xie, Z., Johansen, L. K., Carrington, J. C. et al. (2004) RNA silencing genes control de novo DNA methylation. Science 303, 1336
DOI
ScienceOn
|
140 |
Hannon, G. J. and Rossi, J. J. (2004) Unlocking the potential of the human genome with RNA interference. Nature 431, 371-.378
DOI
ScienceOn
|
141 |
Ngo, H., Tschudi, C., Gull, K., and Ullu, E. (1998) Doublestranded RNA induces mRNA degradation in Trypanosoma brucei. Proc. Natl. Acad. Sci. USA 95, 14687-14692
|
142 |
Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G., et al. (2004) Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell 15, 185-197
DOI
ScienceOn
|
143 |
Martinez, J., Patkaniowska, A., Urlaub, H., Luhrmann, R., and Tuschl, T. (2002) Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110, 563-574
DOI
ScienceOn
|