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Small RNAs: Classification, Biogenesis, and Function  

Kim, V. Narry (Department of Biological Sciences and Institute of Molecular Biology and Genetics, Seoul National University)
Abstract
Eukaryotes produce various types of small RNAs of 19-28 nt in length. With rapidly increasing numbers of small RNAs listed in recent years, we have come to realize how widespread their functions are and how diverse the biogenesis pathways have evolved. At the same time, we are beginning to grasp the common features and rules governing the key steps in small RNA pathways. In this review, I will summarize the current classification, biogenesis, action mechanism and function of these fascinating molecules.
Keywords
Argonaute; MicroRNA; RNA Interference; RNA Silencing; RNase III; siRNA; Small RNA;
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