Metabolic Flux Distribution for -Linolenic Acid Synthetic Pathways in Spirulina platensis |
Meechai Asawin
(Department of Chemical Engineering, School of Engineering, King Mongkut's University of Technology)
Pongakarakun Siriluk (Department of Chemical Engineering, School of Engineering, King Mongkut's University of Technology) Deshnium Patcharaporn (National Center for Genetic Engineering and Biotechnology (BIOTEC)) Cheevadhanarak Supapon (Division of Biotechnology, School of Bioresources and Technology, King Mongkut's University of Technology Thonburi, Bangkuntein campus) Bhumiratana Sakarindr (Department of Chemical Engineering, School of Engineering, King Mongkut's University of Technology, National Center for Genetic Engineering and Biotechnology (BIOTEC)) |
1 | Huang, Y. S., M. S. Manku, and D. F. Horrobin (1984) The effect of dietary cholesterol on blood and liver polyunsaturated fatty acids and on plasma cholesterol in rats fed various types of fatty acid diet. Lipids 19: 664-672 DOI ScienceOn |
2 | Shimizu, S., Y. Shinmen, H. Kawahima, K. Akimoto, and H. Yamada (1988) Fungal mycelia as a novel source of eicosapentaenoic acid. Biochem. Biophys. Res. Comm. 150: 335 DOI ScienceOn |
3 | Berry, A. (1996) Improving production of aromatic compounds in Escherichia coli by metabolic engineering. Trends Biotechnol. 14: 250-256 DOI PUBMED ScienceOn |
4 | Vonshak, A. (1986) Laboratory Techniques for the Cultivation of Microalgae: CRC Handbook of Microalgal Mass Cultures. CRC Press, Florida, USA |
5 | Yang, C., Q. Hua, and K. Shimizu (2000) Energetics and carbon metabolism during growth of microalgal cells un-der photoautotrophic, mixotrophic and cyclic light-auto-trophic/dark-heterotrophic conditions. Biochem. Eng. J. 6: 87-102 DOI ScienceOn |
6 | Ciferri, O. (1983) Spirulina, the edible microorganism. Microbiol. Rev. 47: 551-578 |
7 | Matsuno, T., S. Nagata, M. Iwahashi, T. Koike, and M. Okada (1979) Intensification of color of fancy red carp with zeaxanthin and myxoxanthophyll, major carotenoid constituents of Spirulina. Bull. Jpn. Soc. Sci. Fisheries 45: 627-633 DOI |
8 | Suphatrakul, A. (1996) Effect of Temperature on the Expression of the 12-Desaturase Gene (desA) in Spirulina platensis C1. M.S. Thesis. King Mongkut's University of Technology, Thonburi, Bangkok, Thailand |
9 | Mahajan, G. and M. Kamat (1995) Linolenic acid production from Spirulina platensis. Appl. Microbiol. Biotechnol. 45: 466-469 |
10 | Cohen, Z., M. Reungjitchachawali, W. Siangdung, M. Tanticharoen, and Y. M. Heimer (1993) Herbicide resistant lines of microalgae: Growth and fatty acid composition. Phytochemistry 34: 973-978 DOI ScienceOn |
11 | Stephanopoulos, G., A. A. Aristidou, and J. Nielsen (1998) Metabolic Engineering: Principles and Methodologies. Academic Press, San Diego, USA |
12 | Nichols, B. W. and B. J. B. Wood (1968) The occurrence and biosynthesis of gamma-linolenic acid in blue-green alga, Spirulina platensis. Lipids 3: 46-50 DOI PUBMED ScienceOn |
13 | Dubois, M., K. A. Gilles, J. K. Hamilton, P. A. Rebers, and F. Smith (1956) Colorimetric method for determination of sugar and related substances. Analy. Chem. 28: 350-356 DOI |
14 | Kaneko, T., S. Sato, H. Kotani, A. Tanaka, E. Asumizu, Y. Nakamura, N. Miyajima, and M. Hirosawa (1996) Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC 6803. II Sequence determination of the entire genome and assigment of potential protein-coding regions. DNA Res. 3: 109-136 DOI ScienceOn |
15 | Cohen, Z., A. Vonshak, and A. Richmond (1987) Fatty acid composition of Spirulina strains grown under various environmental conditions. Phytochemistry 26: 2255-2258 DOI ScienceOn |
16 | Hua, Q. and K. Shimizu (1999) Effect of dissoved ozygen concentration on the intracellular flux distribution for pyruvate fermentation. J. Biotechnol. 68: 135-147 DOI ScienceOn |
17 | Laing, W. A. (1992) The regulation of acetyl-CoA carboxylase. Res. Photosyn. 3: 39-42 |
18 | Horrobin, D. F. (1983) The role of essential fatty acids and prostaglandins in the premenstrual syndrome. J. Reprod. Med. 28: 465-468 |
19 | Vonshak, A. (1997) Use of Spirulina biomass, Spirulina platensis (Arthrospira) physiology, cell biology and biotechnology. Taylor & Francis Ltd., UK |
20 | Kaneko, T., S. Sato, H. Kotani, A. Tanaka, E. Asumizu, Y. Nakamura, N. Miyajima, and M. Hirosawa (1996) Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC 6803. II. Sequence determination of the entire genome and assigment of potential protein-coding regions (supplement). DNA Res. 3: 185-209 DOI ScienceOn |
21 | Wright, S. and J. H. Burton (1982) A controlled trial of the treatment of atopic eczema in adults with evening primrose oil (Efamol). Lancet : 1120-1122 |
22 | Cohen, Z. (1986) Product from Microalgae. CRC Press Inc., Florida, USA |
23 | Allen, I. F. and N. G. Homes (1986) Electron Transport and Redox Titration: Photosynthesis Energy Transfuction, a Practical Approach. Information Printing Ltd., Oxford, UK |
24 | Deshnium, P., K. Paithoonrangsarid, A. Suphatrakul, D. Meesapyodsuk, M. Tanticharoen, and S. Cheevadhanarak (2000) Temperature-independent and -dependent expression of desaturase genes in filamentous cyanobacterium Spirulina platensis strain C1 (Arthrospira sp. PCC 9438). FEMS Lett. 184: 207-213 DOI ScienceOn |
25 | Wolf, R. B., R. Kleiman, and R. E. England (1983) New sources of -linolenic acid (Boraginaceae, Scrophulariaceae, Onagraceae, Saxifragaceae). J. Am. Oil. Chem. Soc. 60: 1858 DOI |
26 | Hua, Q., P.C. Fu, C. Yang, and K. Shimizu (1998) Microaerobic lysine fermentations and metabolic flux analysis. Biochem. Eng. J. 2: 89-100 DOI ScienceOn |
27 | Ingram, L. O., P. F. Gomez, X. Lai, M. Moniruzzaman, B. E. Wood, L. P. Yomano, and S. W. York (1998) Metabolic engineering of bacteria for ethanol production. Biotechnol. Bioeng. 58: 204-214 DOI ScienceOn |
28 | Daae, B. E. and A. P. Ison (1999) Classification and sensitivity analysis of a proposed primary metabolic reaction network for Streptomyces lividans. Met. Eng. 1: 153-165 DOI ScienceOn |
29 | Tanticharoen, M., M. Reungjitchachawali, B. Boonag, P. Vonktaveesuk, A. Vonshak, and Z. Cohen (1994) Optimization of -linolenic acid (GLA) production in Spirulina platensis. J. Appl. Phycol. 6: 295-300 DOI ScienceOn |
30 | Vallino, J. J. and G. Stephanopoulos (1993) Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction. Biotechnol. Bioeng. 41: 633-646 DOI |
31 | Gourdon, P. and N. D. Lindley (1999) Metabolic analysis of glutamate production by Corynebacterium glutamicum. Met. Eng. 1: 224-231 DOI ScienceOn |