What Is the Role of Thermodynamics on Protein Stability\ulcorner |
Gummadi, Sathyanarayana N. (Department of Chemical Engineering Indian Institute of Technology-Madras) |
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Protein folding:concepts and perspectives
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Protein folding dynamics
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Some factors in the interpretation of protein denaturation
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Empirical calculation of the relative free energies of peptide binding to the molecular chaperone DnaK
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Enhanced protein thermostability from sitedirected mutations that decrease the entropy of unfolding
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Thermodynamics in biochemical engineering
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ATP lowers the activation enthalpy barriers to DnaK-peptide complex formation and dissociation
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Thermozymes:identifying molecule determinants of protein structural and functional stability
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Thermodynamics of high temperature enzymes:A new predictive model
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Effect of replacing helican glycine residues with alanines on reversible and irreversible stability and production of Aspergillus awamori glucoamylase
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Protein misfolding and disease:protein refolding and therapy
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Solvent entropy-driven searching for protein modelling examined and tested in simplified models
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Protein folding dynamics:the diffusion collision model and experimental data
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Studies on Behviour and production of Extracelluar Pectinases from Aspergillus niger
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Application of response surface methodology to evaluate some aspects on stability of pectolytic enzymes from Aspergillus niger
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Differential salt-induced stabilization of structure in the initial folding intermediate ensemble of barstar
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Protein engineering of subtilisin BPN':Enhanced stabilization through the introduction of two cysteines to form a double bond
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Protein synthesis. The perks of balancing glucose
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Heat capacity of protein folding
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A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides
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Enhancing the feasibility of many biotechnological processes through enzyme deactivation studies
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Predicting DNA duplex stability from the base sequence
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Insights into the stability of native and partially folded states of ubiquitin: effects of cosolvents and denaturants on the thermodynamics of protein folding
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Chemical modifaication and chemical cross-linking for protein/enzyme stabilization
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Viewing protein folding from many perspectives
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Genetic evidence for parallel pathways of chaperone activity in the periplasm of Escherichia coli
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Use of entropies of reaction to predict changes in protein stability: tyrosine-67-phenylalanine variants of rat cytocrome c and yeast iso-1 cytocrmes c
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theory for the folding and stability of globular proteins
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Molecular chaperones:proteins essential for the biogenesis of some macramolecular structures
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Thermodynamics of binding of distal calcium to manganses peroxidase
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Properties of truncated forms ot the elongation factor 1а from the archaeon Sulfolobus solfataricus
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Substantial increase of protein stability by multiple disulfide bonds
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Templating peptide folding on the surface of a micelle: nucleating the formation of a beta-hairpin
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Navigating the folding routes
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Desolvation shell of hydrogen bonds in folded proteins, protein complexes and folding pathways
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Evolution of genetic code, protein synthesis and nucleic acid replication
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Thermodynamic studies of substrate binding and spin transitions in human cytochrome P-450 3A4 expressed in yeast microsomes
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Thermodynamics of the folding of D-glyceraldehyde-3-phosphate dehydrogenase assited by protein disulfide isomerase studied by microcalorimetry
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Conformational landscape of cytochrome c folding studies by microsecond resolved small-angel X-ray scattering
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Mutational effects on cold denaturation and hydration of a protein, Streptomyces subtilisin inhibitor
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The engineering of disulfide bonds, electrostatic interactions and hydrophobic contacts for the stabilization of subtilisin BPN
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The kinetics of formation of native ribonuclease during oxidation of the reduced polypeptide chain
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Themodynamics and kinetics of thermal unfolding of plastocyanin
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Plasma and recombinant thrombin activable fibrinolysis inhibitor(TAFI) and activate TAFI compared with repect to glycosylation, thrombin.thrombomodulin-dependent activation, thermal stability and enzymatic properties
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Thermosensitive mutants of aspergillus awamori by random mutagenesis:inactivation kinetics and structural interpretation
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Role of accessory protein in protein folding
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In situ study of insulin aggregation induced by water-organic solvent interface
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Chaperonin-mediated protein folding at the surface of GroEl through a 'molten globule' like intermediate
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The unfolded protein response: no longer just a special teams player
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Increased the thermostability of Asn 182-Ala mutant Aspergillus awamori glucoamylase
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Increased thermostability of proteins in the presence of amino acids
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The activated complex in chemical reactions
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Trifluoroethanl and colleagues:cosolvents with peptides and proteins
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Chaperones come of age
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How does protein synthesis give rise to the 3D-structure?
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Are there pathways for protein folding?
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Increased hsp22 RNA levels in Drosophila lines genetically selected for increased longevity
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Folding of protein fragments
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Cold denaturation of ubiquitin
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Thermal stability of methanol dehydrogenase is altered by the replacement of enzyme bound <TEX>$Ca^{2+}$</TEX>with <TEX>$Sr^{2+}$</TEX>
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Effect of organic solvents on stability and activity of two related alcohol dehydrogenases:a comparative study
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Characterization of protein and peptide stability and solubility in non-aqueous solvents
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Influence of the carbohydrate moiety on the stability of glycoproteins
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The origin of genetic code
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Impotant amino acid properties for determining the transition state structures of two-state protein mutants
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The statistical-thermodynamic basis for computation of binding affinities:A critical reivew
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Molecular chaperones
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Funnels, pathways and the energy landscape of protein folding:A synthesis.
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The genetic code by numbers
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Triage:Protein fold prediction
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pH and thermal stability studies of chitinase from Trichoderma harzianum
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Enzymes and the supramolecular organization of the living cell. Information transfer within supramolecular edifices and imprinting effects
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Age-related decline in chaperone mediated autophagy
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RNA as an RNA polymerase:net elongation of an RNA primer catalysed by the tetrehymena ribozyme
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The origin of genetic code and protein synthesis
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Protein dynamics, folding and misfolding:from basic physical chemistry to human conformational diseases
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Mechanism based strategies for protein thermostabilization
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