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http://dx.doi.org/10.3344/kjp.2021.34.3.288

Multicenter survey of symptoms, work life, economic status, and quality of life of complex regional pain syndrome patients  

Lee, Jaemoon (Department of Anesthesiology and Pain Medicine, Konkuk University School of Medicine)
Lim, Yun Hee (Department of Anesthesiology and Pain Medicine, Inje University Sanggye Paik Hospital)
Hong, Sung Jun (Department of Anesthesiology and Pain Medicine, Hallym University Kangdong Sacred Heart Hospital)
Jeong, Jae Hun (Department of Anesthesiology and Pain Medicine, Jeong-clinic)
Choi, Hey Ran (Department of Anesthesiology and Pain Medicine, Inje University Seoul Paik Hospital)
Park, Sun Kyung (Department of Anesthesiology and Pain Medicine, Jeju National University School of Medicine)
Kim, Jung Eun (Department of Anesthesiology and Pain Medicine, Hallym University Kangnam Sacred Heart Hospital)
Park, Eun Hi (Department of Anesthesiology and Pain Medicine, Konkuk University School of Medicine)
Kim, Jae Hun (Department of Anesthesiology and Pain Medicine, Konkuk University School of Medicine)
Publication Information
The Korean Journal of Pain / v.34, no.3, 2021 , pp. 288-303 More about this Journal
Abstract
Background: Complex regional pain syndrome (CRPS) is an intractable pain disease with various symptoms. Here, we investigated the disease status, work life, sleep problems, medical insurance, economic status, psychological problems, and quality of life (QOL) of CRPS patients. Methods: CRPS patients from 37 university hospitals in South Korea were surveyed. The survey questionnaire consisted of 24 questions on the following aspects of CRPS patients: sex, age, occupation, cause of injury, activities of daily living (ADL), pain severity, sleep disturbance, level of education, economic status, therapeutic effect, and suicidal ideation. Additionally, the abbreviated World Health Organization Quality of Life (WHOQOL-BREF) questionnaire, consisting of 26 questions, was used to identify the status of QOL. Results: A total of 251 patients completed the questionnaire. According to the survey, 54.2% patients could not perform ADL on their own. Over the previous week, the mean pain score was 7.15 ± 1.78 (out of a total of 10 points); 92.1% of patients had sleep disorders and 80.5% had suicidal ideation, with most patients suffering from psychological problems. The average for each domain of WHOQOL-BREF was as follows: 21.74 ± 14.77 for physical, 25.22 ± 17.66 for psychological, 32.02 ± 22.36 for social relationship, and 30.69 ± 15.83 for environmental (out of a total of 100 points each). Occupation, ADL, sleep time, therapeutic effect, and suicidal ideation were statistically correlated with multiple domains. Conclusions: Most patients had moderate to severe pain, economic problems, limitations of their ADL, sleep problems, psychological problems, and a low QOL score.
Keywords
Activities of Daily Living; Chronic Pain; Complex Regional Pain Syndromes; Economic Status; Educational Status; Occupations; Pain, Intractable; Quality of Life; Sleep Wake Disorders; Suicidal Ideation; Surveys and Questionnaires;
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Times Cited By KSCI : 3  (Citation Analysis)
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1 Galer BS, Henderson J, Perander J, Jensen MP. Course of symptoms and quality of life measurement in Complex Regional Pain Syndrome: a pilot survey. J Pain Symptom Manage 2000; 20: 286-92.   DOI
2 Savas S, Baloglu HH, Ay G, Cerci SS. The effect of sequel symptoms and signs of Complex Regional Pain Syndrome type 1 on upper extremity disability and quality of life. Rheumatol Int 2009; 29: 545-50.   DOI
3 Fishman S, Ballantyne J, Rathmell JP, Bonica JJ. Bonica's management of pain. 4th ed. Baltimore, Lippincott, Williams & Wilkins. 2010, pp xxxiii, 1661.
4 Sharma A, Agarwal S, Broatch J, Raja SN. A web-based cross-sectional epidemiological survey of complex regional pain syndrome. Reg Anesth Pain Med 2009; 34: 110-5.   DOI
5 Chen CK, Phui VE, Nizar AJ, Yeo SN. Percutaneous t2 and t3 radiofrequency sympathectomy for complex regional pain syndrome secondary to brachial plexus injury: a case series. Korean J Pain 2013; 26: 401-5.   DOI
6 Woolf CJ, Salter MW. Neuronal plasticity: increasing the gain in pain. Science 2000; 288: 1765-9.   DOI
7 Vaneker M, Wilder-Smith OH, Schrombges P, Oerlemans HM. Impairments as measured by ISS do not greatly change between one and eight years after CRPS 1 diagnosis. Eur J Pain 2006; 10: 639-44.   DOI
8 Miller MH, Topliss DJ. Chronic upper limb pain syndrome (repetitive strain injury) in the Australian workforce: a systematic cross sectional rheumatological study of 229 patients. J Rheumatol 1988; 15: 1705-12.
9 Kemler MA, Furnee CA. The impact of chronic pain on life in the household. J Pain Symptom Manage 2002; 23: 433-41.   DOI
10 Kemler MA, de Vet HC. Health-related quality of life in chronic refractory reflex sympathetic dystrophy (complex regional pain syndrome type I). J Pain Symptom Manage 2000; 20: 68-76.   DOI
11 Theadom A, Cropley M, Humphrey KL. Exploring the role of sleep and coping in quality of life in fibromyalgia. J Psychosom Res 2007; 62: 145-51.   DOI
12 Kothari DJ, Davis MC, Yeung EW, Tennen HA. Positive affect and pain: mediators of the within-day relation linking sleep quality to activity interference in fibromyalgia. Pain 2015; 156: 540-6.   DOI
13 Maihofner C, Seifert F, Markovic K. Complex regional pain syndromes: new pathophysiological concepts and therapies. Eur J Neurol 2010; 17: 649-60.   DOI
14 Gallicchio L, Kalesan B. Sleep duration and mortality: a systematic review and meta-analysis. J Sleep Res 2009; 18: 148-58.   DOI
15 Sathvik BS, Parthasarathi G, Narahari MG, Gurudev KC. An assessment of the quality of life in hemodialysis patients using the WHOQOL-BREF questionnaire. Indian J Nephrol 2008; 18: 141-9.   DOI
16 Shin NY, Kang DH, Jang JH, Park SY, Hwang JY, Kim SN, et al. Impaired recognition of social emotion in patients with complex regional pain syndrome. J Pain 2013; 14: 1304-9.   DOI
17 Marinus J, Van Hilten JJ. Clinical expression profiles of complex regional pain syndrome, fibromyalgia and a-specific repetitive strain injury: more common denominators than pain? Disabil Rehabil 2006; 28: 351-62.   DOI
18 Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, et al. A classification of chronic pain for ICD-11. Pain 2015; 156: 1003-7.   DOI
19 Sohn HS, Lee DH, Lee KJ, Noh EC, Choi SH, Jang JH, et al. Impaired empathic abilities among patients with Complex Regional Pain Syndrome (Type I). Psychiatry Investig 2016; 13: 34-42.   DOI
20 Rand SE, Basu S, Khalid S. Complex regional pain syndrome: current diagnostic and treatment considerations. Curr Sports Med Rep 2019; 18: 325-9.   DOI
21 Lee WJ, Jung CH, Hwang JY, Seong SJ, Han CH, Park JW, et al. Prognostic factors in complex regional pain syndrome type 1 occurring in the Korean army. Pain Med 2019; 20: 1989-96.   DOI
22 Liu Y, Wheaton AG, Chapman DP, Croft JB. Sleep duration and chronic diseases among U.S. adults age 45 years and older: evidence from the 2010 Behavioral Risk Factor Surveillance System. Sleep 2013; 36: 1421-7.   DOI
23 Bruehl S, Harden RN, Galer BS, Saltz S, Bertram M, Backonja M, et al. External validation of IASP diagnostic criteria for Complex Regional Pain Syndrome and proposed research diagnostic criteria. International Association for the Study of Pain. Pain 1999; 81: 147-54.   DOI
24 Kang JE, Kim YC, Lee SC, Kim JH. Relationship between complex regional pain syndrome and working life: a Korean study. J Korean Med Sci 2012; 27: 929-33.   DOI
25 Zhai L, Zhang H, Zhang D. Sleep duration and depression among adults: a meta-analysis of prospective studies. Depress Anxiety 2015; 32: 664-70.   DOI
26 Chiu WT, Huang SJ, Hwang HF, Tsauo JY, Chen CF, Tsai SH, et al. Use of the WHOQOL-BREF for evaluating persons with traumatic brain injury. J Neurotrauma 2006; 23: 1609-20.   DOI
27 Brunner F, Nauer M, Bachmann LM. Poor prognostic factors in complex regional pain syndrome 1: a Delphi survey. J Rehabil Med 2011; 43: 783-6.   DOI
28 Birklein F, O'Neill D, Schlereth T. Complex regional pain syndrome: an optimistic perspective. Neurology 2015; 84: 89-96.   DOI
29 Grieve S, Llewellyn A, Jones L, Manns S, Glanville V, McCabe CS. Complex regional pain syndrome: an international survey of clinical practice. Eur J Pain 2019; 23: 1890-903.   DOI
30 Li Z, Smith BP, Smith TL, Koman LA. Diagnosis and management of complex regional pain syndrome complicating upper extremity recovery. J Hand Ther 2005; 18: 270-6.   DOI
31 Harden RN, Oaklander AL, Burton AW, Perez RS, Richardson K, Swan M, et al. Complex regional pain syndrome: practical diagnostic and treatment guidelines, 4th edition. Pain Med 2013; 14: 180-229.   DOI
32 Feldman SI, Downey G, Schaffer-Neitz R. Pain, negative mood, and perceived support in chronic pain patients: a daily diary study of people with reflex sympathetic dystrophy syndrome. J Consult Clin Psychol 1999; 67: 776-85.   DOI
33 Sandroni P, Benrud-Larson LM, McClelland RL, Low PA. Complex regional pain syndrome type I: incidence and prevalence in Olmsted county, a population-based study. Pain 2003; 103: 199-207.   DOI
34 Lee DH, Noh EC, Kim YC, Hwang JY, Kim SN, Jang JH, et al. Risk factors for suicidal ideation among patients with complex regional pain syndrome. Psychiatry Investig 2014; 11: 32-8.   DOI
35 Lee SJ, Yoo YM, You JA, Shin SW, Kim TK, Abdi S, et al. Successful removal of permanent spinal cord stimulators in patients with complex regional pain syndrome after complete relief of pain. Korean J Pain 2019; 32: 47-50.   DOI
36 Chae WS, Kim SH, Cho SH, Lee JH, Lee MS. Reduction in mechanical allodynia in complex regional pain syndrome patients with ultrasound-guided pulsed radiofrequency treatment of the superficial peroneal nerve. Korean J Pain 2016; 29: 266-9.   DOI
37 Jeon SG, Choi EJ, Lee PB, Lee YJ, Kim MS, Seo JH, et al. Do severity score and skin temperature asymmetry correlate with the subjective pain score in the patients with complex regional pain syndrome? Korean J Pain 2014; 27: 339-44.   DOI
38 Kim H, Lee CH, Kim SH, Kim YD. Epidemiology of complex regional pain syndrome in Korea: an electronic population health data study. PLoS One 2018; 13: e0198147.   DOI
39 Goebel A. Complex regional pain syndrome in adults. Rheumatology (Oxford) 2011; 50: 1739-50.   DOI
40 Littlejohn G. Therapy: bisphosphonates for early complex regional pain syndrome. Nat Rev Rheumatol 2013; 9: 199-200.   DOI
41 Ok SJ, Yang JY, Son JH, Jeong WJ, Lee YS, Kim WY, et al. Management of complex regional pain syndrome type 1 with total spinal block. Korean J Pain 2010; 23: 70-3.   DOI
42 Geertzen JH, Dijkstra PU, Groothoff JW, ten Duis HJ, Eisma WH. Reflex sympathetic dystrophy of the upper extremity--a 5.5-year follow-up. Part I. Impairments and perceived disability. Acta Orthop Scand Suppl 1998; 279: 12-8.
43 DeGood DE, Cundiff GW, Adams LE, Shutty MS Jr. A psychosocial and behavioral comparison of reflex sympathetic dystrophy, low back pain, and headache patients. Pain 1993; 54: 317-22.   DOI
44 Grandner MA, Chakravorty S, Perlis ML, Oliver L, Gurubhagavatula I. Habitual sleep duration associated with self-reported and objectively determined cardiometabolic risk factors. Sleep Med 2014; 15: 42-50.   DOI