Effects of Palonosetron, a 5-HT3 Receptor Antagonist, on Mechanical Allodynia in a Rat Model of Postoperative Pain |
Jung, Ki Tae
(Department of Anesthesiology and Pain Medicine, School of Medicine, Chosun University)
Yoon, Myung Ha (Medical School, Chonnam National University) Lee, Hyun Young (Department of Anesthesiology and Pain Medicine, School of Medicine, Chosun University) Yu, Bo Yeon (Department of Anesthesiology and Pain Medicine, School of Medicine, Chosun University) Kim, Dong Kyu (Department of Anesthesiology and Pain Medicine, School of Medicine, Chosun University) Lim, Kyung Joon (Department of Anesthesiology and Pain Medicine, School of Medicine, Chosun University) |
1 | McCleane GJ, Suzuki R, Dickenson AH. Does a single intravenous injection of the 5HT3 receptor antagonist ondansetron have an analgesic effect in neuropathic pain? A double-blinded, placebo-controlled cross-over study. Anesth Analg 2003; 97: 1474-1478. |
2 | Sommer C. Is serotonin hyperalgesic or analgesic? Curr Pain Headache Rep 2006; 10: 101-106. DOI ScienceOn |
3 | Eschalier A, Kayser V, Guilbaud G. Influence of a specific 5-HT3 antagonist on carrageenan-induced hyperalgesia in rats. Pain 1989; 36: 249-255. DOI ScienceOn |
4 | Park SK, Cho EJ. A randomized, double-blind trial of palonosetron compared with ondansetron in preventing postoperative nausea and vomiting after gynaecological laparoscopic surgery. J Int Med Res 2011; 39: 399-407. DOI ScienceOn |
5 | Yaksh TL, Rudy TA. Chronic catheterization of the spinal subarachnoid space. Physiol Behav 1976; 17: 1031-1036. DOI ScienceOn |
6 | Brennan TJ, Vandermeulen EP, Gebhart GF. Characterization of a rat model of incisional pain. Pain 1996; 64: 493-501. DOI ScienceOn |
7 | Shin DJ, Yoon MH, Lee HG, Kim WM, Park BY, Kim YO, et al. The effect of treatment with intrathecal ginsenosides in a rat model of postoperative pain. Korean J Pain 2007; 20: 100-105. DOI ScienceOn |
8 | Wong EH, Clark R, Leung E, Loury D, Bonhaus DW, Jakeman L, et al. The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitro. Br J Pharmacol 1995; 114: 851-859. DOI ScienceOn |
9 | Kovac AL, Eberhart L, Kotarski J, Clerici G, Apfel C; Palonosetron 04-07 Study Group. A randomized, doubleblind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo in preventing postoperative nausea and vomiting over a 72-hour period. Anesth Analg 2008; 107: 439-444. DOI ScienceOn |
10 | Alhaider AA, Lei SZ, Wilcox GL. Spinal 5-HT3 receptormediated antinociception: possible release of GABA. J Neurosci 1991; 11: 1881-1888. |
11 | Suzuki R, Rygh LJ, Dickenson AH. Bad news from the brain: descending 5-HT pathways that control spinal pain processing. Trends Pharmacol Sci 2004; 25: 613-617. DOI ScienceOn |
12 | Suzuki R, Morcuende S, Webber M, Hunt SP, Dickenson AH. Superficial NK1-expressing neurons control spinal excitability through activation of descending pathways. Nat Neurosci 2002; 5: 1319-1326. DOI ScienceOn |
13 | Rahman W, Suzuki R, Hunt SP, Dickenson AH. Selective ablation of dorsal horn NK1 expressing cells reveals a modulation of spinal alpha2-adrenergic inhibition of dorsal horn neurones. Neuropharmacology 2008; 54: 1208-1214. DOI ScienceOn |
14 | Oatway MA, Chen Y, Weaver LC. The 5-HT3 receptor facilitates at-level mechanical allodynia following spinal cord injury. Pain 2004; 110: 259-268. DOI ScienceOn |
15 | Zeitz KP, Guy N, Malmberg AB, Dirajlal S, Martin WJ, Sun L, et al. The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. J Neurosci 2002; 22: 1010-1019. |
16 | Vandermeulen EP, Brennan TJ. Alterations in ascending dorsal horn neurons by a surgical incision in the rat foot. Anesthesiology 2000; 93: 1294-1302. DOI ScienceOn |
17 | Zahn PK, Pogatzki EM, Brennan TJ. Mechanisms for pain caused by incisions. Reg Anesth Pain Med 2002; 27: 514-516. DOI |
18 | Pogatzki EM, Urban MO, Brennan TJ, Gebhart GF. Role of the rostral medial medulla in the development of primary and secondary hyperalgesia after incision in the rat. Anesthesiology 2002; 96: 1153-1160. DOI ScienceOn |
19 | Rahman W, Suzuki R, Webber M, Hunt SP, Dickenson AH. Depletion of endogenous spinal 5-HT attenuates the behavioural hypersensitivity to mechanical and cooling stimuli induced by spinal nerve ligation. Pain 2006; 123: 264-274. DOI ScienceOn |
20 | Kress M, Reeh PW, Vyklicky L. An interaction of inflammatory mediators and protons in small diameter dorsal root ganglion neurons of the rat. Neurosci Lett 1997; 224: 37-40. DOI ScienceOn |
21 | Faerber L, Drechsler S, Ladenburger S, Gschaidmeier H, Fischer W. The neuronal 5-HT3 receptor network after 20 years of research--evolving concepts in management of pain and inflammation. Eur J Pharmacol 2007; 560: 1-8. DOI ScienceOn |
22 | Jeong CY, Bae HB, Park HC, Choi JI, Yoon MH. Evaluation of the role of 5-hydroxytryptamine receptor subtypes in the regulation of nociceptive transmission in the rat spinal cord. Korean J Anesthesiol 2004; 47: 856-861. DOI |
23 | Ali Z, Wu G, Kozlov A, Barasi S. The role of 5HT3 in nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies. Neurosci Lett 1996; 208: 203-207. DOI ScienceOn |