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http://dx.doi.org/10.3344/kjp.2013.26.1.80

Stevens-Johnson Syndrome Induced by Carbamazepine Treatment in a Patient Who Previously Had Carbamazepine Induced Pruritus - A Case Report -  

Bae, Hyun Min (Department of Anesthesiology and Pain Medicine, Catholic Medical Center, School of Medicine, The Catholic University of Korea)
Park, Yoo Jung (Department of Anesthesiology and Pain Medicine, Catholic Medical Center, School of Medicine, The Catholic University of Korea)
Kim, Young Hoon (Department of Anesthesiology and Pain Medicine, Catholic Medical Center, School of Medicine, The Catholic University of Korea)
Moon, Dong Eon (Department of Anesthesiology and Pain Medicine, Catholic Medical Center, School of Medicine, The Catholic University of Korea)
Publication Information
The Korean Journal of Pain / v.26, no.1, 2013 , pp. 80-83 More about this Journal
Abstract
Stevens-Johnson syndrome (SJS) is a rare but life-threatening skin reaction disease and carbamazepine is one of its most common causes. We report a case of SJS secondary to carbamazepine in a patient with previous pruritus due to carbamazepine which was given for treatment of trigeminal neuralgia. We would like to caution all providers that carbamazepine readministration should be avoided in the patient with a previous history of SJS or adverse skin reaction. In addition, we strongly recommend gradual titration when initiating treatment with carbamazepine.
Keywords
carbamazepine; drug hypersensitivity reaction; Stevens-Johnson syndrome; trigerminal neuralgia;
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