Effectiveness and Tolerance of a Locust Bean Gum-Thickened Formula: A Real-Life Study |
Tounian, Patrick
(Nutrition et Gastroenterologie Pediatriques, Hopital Trousseau, APHP, Sorbonne Universite)
Meunier, Leo (Danone Food Safety Centre) Speijers, Gerrit (General Health Effects Toxicology Safety Food (GETS)) Oozeer, Raish (Nutricia Research) Vandenplas, Yvan (KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel) |
1 | Iacono G, Vetrano S, Cataldo F, Ziino O, Russo A, Lorello D, et al. Clinical trial with thickened feeding for treatment of regurgitation in infants. Dig Liver Dis 2002;34:532-3. |
2 | Miyazawa R, Tomomasa T, Kaneko H, Morikawa A. Effect of formula thickened with locust bean gum on gastric emptying in infants. J Paediatr Child Health 2006;42:808-12. DOI |
3 | Meunier L, Garthoff JA, Schaafsma A, Krul L, Schrijver J, van Goudoever JB, et al. Locust bean gum safety in neonates and young infants: an integrated review of the toxicological database and clinical evidence. Regul Toxicol Pharmacol 2014;70:155-69. DOI |
4 | Huet F, Abrahamse-Berkeveld M, Tims S, Simeoni U, Beley G, Savagner C, et al. Partly fermented infant formulae with specific oligosaccharides support adequate infant growth and are well-tolerated. J Pediatr Gastroenterol Nutr 2016;63:e43-53. DOI |
5 | Lewis SJ, Heaton KW. Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol 1997;32:920-4. DOI |
6 | Dupont C, Vandenplas Y; SONAR Study Group. Efficacy and tolerance of a new anti-regurgitation formula. Pediatr Gastroenterol Hepatol Nutr 2016;19:104-9. DOI |
7 | Agresti A. An introduction to categorical data analysis. Hoboken: John Wiley & Sons, Inc., 2006. |
8 | Gonzalez-Bermudez CA, Lopez-Nicolas R, Peso-Echarri P, Frontela-Saseta C, Martinez-Gracia C. Effects of different thickening agents on infant gut microbiota. Food Funct 2018;9:1768-78. DOI |
9 | Levtchenko E, Hauser B, Vandenplas Y. Nutritional value of an "anti-regurgitation" formula. Acta Gastroenterol Belg 1998;61:285-7. |
10 | Bosscher D, Robberecht H, Van Cauwenbergh R, Van Caillie-Bertrand M, Deelstra H. Binding of mineral elements to locust bean gum influences availability in vitro. Biol Trace Elem Res 2001;81:79-92. DOI |
11 | Benninga MA, Faure C, Hyman PE, St James Roberts I, Schechter NL, Nurko S. Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology 2016;150:1443-55. DOI |
12 | Herrera AR, Ludwig T, Bouritius H, Rubio RP, Munoz A, Agosti M, et al. OP-18 The combination of scGOS/lcFOS and fermented infant formula softens stools of infants compared to unfermented infant formula without scGOS/lcFOS. J Pediatr Gastroenterol Nutr 2015;61:516-7. |
13 | Beghin L, Marchandise X, Lien E, Bricout M, Bernet JP, Lienhardt JF, et al. Growth, stool consistency and bone mineral content in healthy term infants fed sn-2-palmitate-enriched starter infant formula: A randomized, double-blind, multicentre clinical trial. Clin Nutr 2019;38:1023-30. DOI |
14 | Vandenplas Y, Ludwig T, Bouritius H, Alliet P, Forde D, Peeters S, et al. Randomised controlled trial demonstrates that fermented infant formula with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides reduces the incidence of infantile colic. Acta Paediatr 2017;106:1150-8. DOI |
15 | Boehm G, Lidestri M, Casetta P, Jelinek J, Negretti F, Stahl B, et al. Supplementation of a bovine milk formula with an oligosaccharide mixture increases counts of faecal bifidobacteria in preterm infants. Arch Dis Child Fetal Neonatal Ed 2002;86:F178-81. DOI |
16 | Vandenplas Y, Leluyer B, Cazaubiel M, Housez B, Bocquet A. Double-blind comparative trial with 2 antiregurgitation formulae. J Pediatr Gastroenterol Nutr 2013;57:389-93. DOI |
17 | Barr RG. Colic and crying syndromes in infants. Pediatrics 1998;102(5 Suppl E):1282-6. |
18 | Iglowstein I, Jenni OG, Molinari L, Largo RH. Sleep duration from infancy to adolescence: reference values and generational trends. Pediatrics 2003;111:302-7. DOI |
19 | Hegar B, Rantos R, Firmansyah A, De Schepper J, Vandenplas Y. Natural evolution of infantile regurgitation versus the efficacy of thickened formula. J Pediatr Gastroenterol Nutr 2008;47:26-30. DOI |
20 | Rosen R, Vandenplas Y, Singendonk M, Cabana M, DiLorenzo C, Gottrand F, et al. Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr 2018;66:516-54. DOI |
21 | Salvatore S, Savino F, Singendonk M, Tabbers M, Benninga MA, Staiano A, et al. Thickened infant formula: What to know. Nutrition 2018;49:51-6. DOI |
22 | Gonzalez-Bermudez CA, Frontela-Saseta C, Lopez-Nicolas R, Ros-Berruezo G, Martinez-Gracia C. Effect of adding different thickening agents on the viscosity properties and in vitro mineral availability of infant formula. Food Chem 2014;159:5-11. DOI |
23 | Kawamura Y, Smith J, Rao MV. Carob bean gum, 82nd JECFA-Chemical and Technical Assessment (CTA). Rome: Food and Agriculture Organization of the United Nations, 2016:1-6. |
![]() |