Browse > Article
http://dx.doi.org/10.5223/pghn.2019.22.6.601

Endoscopic Management of Pancreaticopleural Fistula in a Child with Hereditary Pancreatitis  

Lee, Dahye (Department of Pediatrics, Seoul National University College of Medicine)
Lee, Eun Joo (Department of Pediatrics, Seoul National University College of Medicine)
Kim, Ju Whi (Department of Pediatrics, Seoul National University College of Medicine)
Moon, Jin Soo (Department of Pediatrics, Seoul National University College of Medicine)
Kim, Yong-Tae (Department of Internal Medicine, Seoul National University College of Medicine)
Ko, Jae Sung (Department of Pediatrics, Seoul National University College of Medicine)
Publication Information
Pediatric Gastroenterology, Hepatology & Nutrition / v.22, no.6, 2019 , pp. 601-607 More about this Journal
Abstract
Pancreaticopleural fistula (PPF) a fistulous connection between the pancreas and pleural space due to prolonged chronic pancreatitis (CP). PPF is a very rare complication which presents in 0.4% of chronic pancreatitis cases, especially among children. We report a case involving a 3-year-old boy who presented with pleural effusion caused by a PPF, a complication of hereditary pancreatitis, which was, for the first time in Korea, successfully managed with endoscopic treatment. Chest radiography and computed tomography showed massive pleural effusion. Percutaneous catheter drainage was performed. High amylase levels were observed in the pleural fluid and serum, suggesting PPF. The patient was managed with bowel rest and octreotide infusion. Endoscopic retrograde cholangiopancreatography revealed CP, and pleural effusion was successfully managed with stent placement. PRSS1 genetic screening revealed R122H mutation.
Keywords
Pancreaticopleural fistula; Endoscopic retrograde cholangiopancreatography; Chronic pancreatitis; Pancreatic fistula; Pleural effusion;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Gariepy CE, Heyman MB, Lowe ME, Pohl JF, Werlin SL, Wilschanski M, et al. Causal evaluation of acute recurrent and chronic pancreatitis in children: consensus from the INSPPIRE group. J Pediatr Gastroenterol Nutr 2017;64:95-103.   DOI
2 Shin JY, Oh DS, Rheu JM, Shim JO, Park JS, Ko JS, et al. A case of hereditary pancreatitis with a N29I mutation in the cationic trypsinogen gene. Korean J Pediatr 2006;49:1111-5.   DOI
3 Keim V, Bauer N, Teich N, Simon P, Lerch MM, Mossner J. Clinical characterization of patients with hereditary pancreatitis and mutations in the cationic trypsinogen gene. Am J Med 2001;111:622-6.   DOI
4 Howes N, Lerch MM, Greenhalf W, Stocken DD, Ellis I, Simon P, et al.; European Registry of Hereditary Pancreatitis and Pancreatic Cancer (EUROPAC). Clinical and genetic characteristics of hereditary pancreatitis in Europe. Clin Gastroenterol Hepatol 2004;2:252-61.   DOI
5 Cazzo E, Apodaca-Rueda M, Gestic MA, Chaim FHM, Saito HPA, Utrini MP, et al. Management of pancreaticopleural fistulas secondary to chronic pancreatitis. Arq Bras Cir Dig 2017;30:225-8.   DOI
6 Francisco E, Mendes M, Vale S, Ferreira J. Pancreaticopleural fistula: an unusual complication of pancreatitis. BMJ Case Rep 2015;2015:bcr2014208814.
7 Ali T, Srinivasan N, Le V, Chimpiri AR, Tierney WM. Pancreaticopleural fistula. Pancreas 2009;38:e26-31.   DOI
8 Neher JR, Brady PG, Pinkas H, Ramos M. Pancreaticopleural fistula in chronic pancreatitis: resolution with endoscopic therapy. Gastrointest Endosc 2000;52:416-8.   DOI
9 Wronski M, Slodkowski M, Cebulski W, Moronczyk D, Krasnodebski IW. Optimizing management of pancreaticopleural fistulas. World J Gastroenterol 2011;17:4696-703.   DOI
10 Vue PM, McFann K, Narkewicz MR. Genetic mutations in pediatric pancreatitis. Pancreas 2016;45:992-6.   DOI
11 Wakefield S, Tutty B, Britton J. Pancreaticopleural fistula: a rare complication of chronic pancreatitis. Postgrad Med J 1996;72:115-6.   DOI
12 Dhebri AR, Ferran N. Nonsurgical management of pancreaticopleural fistula. JOP 2005;6:152-61.
13 Hastier P, Rouquier P, Buckley M, Simler JM, Dumas R, Delmont JP. Endoscopic treatment of wirsungocysto-pleural fistula. Eur J Gastroenterol Hepatol 1998;10:527-9.   DOI
14 Ranuh R, Ditchfield M, Clarnette T, Auldist A, Oliver MR. Surgical management of a pancreaticopleural fistula in a child with chronic pancreatitis. J Pediatr Surg 2005;40:1810-2.   DOI
15 Altasan T, Aljehani Y, Almalki A, Algamdi S, Talag A, Alkattan K. Pancreaticopleural fistula: an overlooked entity. Asian Cardiovasc Thorac Ann 2014;22:98-101.   DOI
16 Rockey DC, Cello JP. Pancreaticopleural fistula. Report of 7 patients and review of the literature. Medicine (Baltimore) 1990;69:332-44.   DOI
17 Xiao AY, Tan ML, Wu LM, Asrani VM, Windsor JA, Yadav D, et al. Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies. Lancet Gastroenterol Hepatol 2016;1:45-55.   DOI
18 Yadav D, Timmons L, Benson JT, Dierkhising RA, Chari ST. Incidence, prevalence, and survival of chronic pancreatitis: a population-based study. Am J Gastroenterol 2011;106:2192-9.   DOI
19 Spanier B, Bruno MJ, Dijkgraaf MG. Incidence and mortality of acute and chronic pancreatitis in the Netherlands: a nationwide record-linked cohort study for the years 1995-2005. World J Gastroenterol 2013;19:3018-26.   DOI