[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5223/pghn.2013.16.3.143

Obesity, Inflammation and Diet

Lee, Hansongyi (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)
Lee, In Seok (Nutrition Team, Kyung Hee University Medical Center)
Choue, Ryowon (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)

Publication Information

Pediatric Gastroenterology, Hepatology & Nutrition / v.16, no.3, 2013 , pp. 143-152 More about this Journal

Abstract

Obesity is a state in which there is an over-accumulation of subcutaneous and/or abdominal adipose tissue. This adipose tissue is no longer considered inert and mainly devoted to storing energy; it is emerging as an active tissue in the regulation of physiological and pathological processes, including immunity and inflammation. Adipose tissue produces and releases a variety of adipokines (leptin, adiponectin, resistin, and visfatin), as well as pro- and anti-inflammatory cytokines (tumor necrosis factor- ${\alpha}$ , interleukin [IL]-4, IL-6, and others). Adipose tissue is also implicated in the development of chronic metabolic diseases such as type 2 diabetes mellitus or cardiovascular disease. Obesity is thus an underlying condition for inflammatory and metabolic diseases. Diet or dietary patterns play critical roles in obesity and other pathophysiological conditions. A healthy diet and some nutrients are generally considered beneficial; however, some dietary nutrients are still considered controversial. In this article, dietary factors that influence inflammation associated with obesity are discussed.

Keywords

Obesity; Adipose tissue; Inflammation; Diet; Epidemiology; Clinical trial;

Citations & Related Records

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