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Comparison of dose-variation in skin due to Set-up error in case of radiation therapy for left breast using Volumetric Modulated Arc Therapy(VMAT)  

Kwon, Yongjae (Department Of Radiation Oncology, Yonsei University Yonsei Cancer Center)
Park, Ryeunghwang (Department Of Radiation Oncology, Yonsei University Yonsei Cancer Center)
Kim, Seyoung (Department Of Radiation Oncology, Yonsei University Yonsei Cancer Center)
Jung, Dongmin (Department Of Radiation Oncology, Yonsei University Yonsei Cancer Center)
Baek, Jonggeol (Department Of Radiation Oncology, Yonsei University Yonsei Cancer Center)
Cho, Jeonghee (Department Of Radiation Oncology, Yonsei University Yonsei Cancer Center)
Publication Information
The Journal of Korean Society for Radiation Therapy / v.33, no., 2021 , pp. 55-62 More about this Journal
Abstract
Purpose: This study aims to contribute to the reduction of complications of breast cancer radiation therapy by analyzing skin dose differences due to Set-up error. Materials and Method: Pseudo breast was produced using a 3D printer, applied to the phantom, and images were acquired through CT. Treatment plan was carried out that the PTV, which contains 95% of the prescription dose, could be more than 95% of the volume, so that Dmax did not exceed 107% of the prescription dose. The Set-up error was evaluated by applying ±1mm/±3mm/±5mm to the X-axis, Y-axis, and Z-axis. Results: The dose-variation in skin due to Set-up error was approximately 106% to 123% compared to prescription dose, and the highest dose in skin was 49.24 Gy at 5mm Set-up error in the lateral direction of the X-axis. More than 107% of the prescription dose was the widest at 6.87 cc in skin lateral. Conclusions: If a Set-up error occurs during left breast cancer VMAT, a great difference in skin dose was shown in the lateral direction of the X-axis. If more effort is made to align the X-axis of the breast treated during CBCT registration, the dose-variation of skin will be reduced.
Keywords
CBCT; Set-up error; radiation dermatitis; skin dose;
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  • Reference
1 Central Cancer Registry Center. Annual Report of the Central Cancer in Korea: 2018. Seoul; Ministry for Health, Welfare and Family Affairs, 2020
2 Central Cancer Registry Center in Korea. Cancer Facts & Figures 2017. Seoul: Ministrty of Health and Welfare; 2017
3 김민석, 전수동, 배선명 등: Prone Breast Phantom을 이용한 couch 산란영향 평가. 대한방사선치료학회지 2017;29:43-51
4 Haffty BG, Buchholz TA, Perez CA. Early stage breast cancer. In: Halperin EC, Perez CA, Brady LW, eds. Principles and Practice of Radiation Oncology. 5th ed. Philadelphia, Lippincott Williams & Wilkins. 2007:1175-1291
5 Collen EB, Mayer MN. Acute effects of radiation treatment: skin reactions. Can Vet J 2006;47:931-935
6 Patrick N. McDermott Ph.D: Surface dose and acute skin reactions in external beam breast radiotherapy. Medical Dosimetry 2020;45:153-158   DOI
7 Fujishiro S, Mitsumori M, Kokubo M, et al. Cosmetic results and complications after breast conserving therapy for early breast cancer. Breast Cancer 2000;7:57-63   DOI
8 RTOG 1005 (Radiation Therapy Oncology Group 1005). 2011;20-22
9 Adam J Kole, Lauren Kole, Meena S Moran. Acute radiation dermatitis in breast cancer patients: challenges and solutions. Breast Cancer- Targets and Therapy. 2017;9:313-323   DOI
10 Stephen F. Kry,a Susan A. Smith, Rita Weathers, et al. Skin dose during radiotherapy: a summary and general estimation technique. Journal of applied clinical medical physics 2012;13(3)
11 Taylan Tugrul. Absorption ratio of treatment couch and effect on surface and build-up region doses. Rep Pract Oncol Radiother. 2018;23(1):1-5   DOI
12 Iaccarino G, Pinnaro P, Landoni V, et al. Single fraction partial breast irradiation in prone position. J Exp Clin Cancer Res. 2007;26(4):543-52.