Browse > Article

The Evaluation of the dose calculation algorithm(AAA)'s Accuracy in Case of a Radiation Therapy on Inhomogeneous tissues using FFF beam  

Kim, In Woo (Department of Radiation Oncology, Seoul National University Hospital)
Chae, Seung Hoon (Department of Radiation Oncology, Seoul National University Hospital)
Kim, Min Jung (Department of Radiation Oncology, Seoul National University Hospital)
Kim, Bo Gyoum (Department of Radiation Oncology, Seoul National University Hospital)
Kim, Chan Yong (Department of Radiation Oncology, Seoul National University Hospital)
Park, So Yeon (Department of Radiation Oncology, Seoul National University Hospital)
Yoo, Suk Hyun (Department of Radiation Oncology, Seoul National University Hospital)
Publication Information
The Journal of Korean Society for Radiation Therapy / v.26, no.2, 2014 , pp. 321-327 More about this Journal
Abstract
Purpose : To verify the accuracy of the Ecilpse's dose calculation algorithm(AAA:Analytic anisotropic algorithm) in case of a radiation treatment on Inhomogeneous tissues using FFF beam comparing dose distribution at TPS with actual distribution. Materials and Methods : After acquiring CT images for radiation treatment by the location of tumors and sizes using the solid water phantoms, cork and chest tumor phantom made of paraffin, we established the treatment plan for 6MV photon therapy using our radiation treatment planning system for chest SABR, Ecilpse's AAA(Analytic anisotropic algorithm). According to the completed plan, using our TrueBeam STx(Varian medical system, Palo Alto, CA), we irradiated radiation on the chest tumor phantom on which EBT2 films are inserted and evaluated the dose value of the treatment plan and that of the actual phantom on Inhomogeneous tissue. Results : The difference of the dose value between TPS and measurement at the medial target is 1.28~2.7%, and, at the side of target including inhomogeneous tissues, the difference is 2.02%~7.40% at Ant, 4.46%~14.84% at Post, 0.98%~7.12% at Rt, 1.36%~4.08% at Lt, 2.38%~4.98% at Sup, and 0.94%~3.54% at Inf. Conclusion : In this study, we discovered the possibility of dose calculation's errors caused by FFF beam's characteristics and the inhomogeneous tissues when we do SBRT for inhomogeneous tissues. SBRT which is most popular therapy method needs high accuracy because it irradiates high dose radiation in small fraction. So, it is supposed that ideal treatment is possible if we minimize the errors when planning for treatment through more study about organ's characteristics like Inhomogeneous tissues and FFF beam's characteristics.
Keywords
SABR; FFF; VMAT Analytic Anisotropic Algorithm; Inhomogeneity;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Palma D, Tyldesley S, Sheehan F, et al: Stage I nonsmall cell lung cancer (NSCLC) in patients aged 75 years and above: Does age determine survival after radical treatment J Thorac Oncol 2010;5:818-824   DOI
2 Grutters JPC, Kessels AGH, Pijls-Johannesma M, et al: Comparison of the effectiveness of radiotherapy with photons, protons and carbon-ions for non-small cell lung cancer: A meta-analysis. Radiother Oncol 2010;95:32-40   DOI   ScienceOn
3 Rowell NP, Williams CJ: Radical radiotherapy for stage I/II non-small cell lung cancer in patients not sufficiently fit for or declining surgery (medically inoperable): A systematic review. Thorax 2001;56:628-638   DOI
4 Timmerman R, Paulus R, Galvin J, et al: Stereotactic body radiation therapy for inoperable early stage lung cancer. JAMA 2010;303:1070-1076   DOI   ScienceOn
5 Nguyen NP, Garland L, Welsh J, et al: Can stereotactic fractionated radiation therapy become the standard of care for early stage non-small cell lung carcinoma. Cancer Treat Rev 2008;34:719-727   DOI   ScienceOn
6 Haasbeek CJ, Lagerwaard FJ, Antonisse ME, et al: Stage I nonsmall cell lung cancer in patients aged /75 years: Outcomes after stereotactic radiotherapy. Cancer 2010;116:406-414   DOI   ScienceOn
7 David Palma, Otto Visser, Frank J. Lagerwaard, Jose Belderbos, et al: Impact of Introducing Stereotactic Lung Radiotherapy for Elderly Patients With Stage 1 Non-small-cell Lung Cancer: A Population-Based Timetrend Analysis. J Clin Oncol 28:5153-5159
8 Chan Yong Kim, Jae Hee Lee, Yong Kook Kwak, Min Yong Ha : Evalauation of Planning Dose Accuaracy in Case of Radiation Treatment on Inhomogeneous Organ Structure, 대한방사선치료학회지 제 25권 제2호, 2013
9 HEIDI S. RONDE1.2 & LONE HOFFMANN1 : Validation of Varian's AAA Algorithm with focus on lung treatment, Acta Oncologica, 2009, 28:209-215
10 Haeyoung Kim, MD : Results and prognostic factors of hypofractionated streotactic radiation therapy for primary or metastatic lung cancer, Journal of thoractic oncology, volume 5, Number 4, April 2010
11 AAPM TG-65: Tissue Inhomogeneity Corrections for Mega-voltage Photon Beams. American association of Physicists in medicine (2004)