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http://dx.doi.org/10.3338/kjc.2008.19.2.194

Mucinous Tubular and Spindle Cell Carcinoma of the Kidney: Touch Imprint Cytologic and Histologic Findings - A Case Report -  

Won, Kyu-Yeoun (Department of Pathology, East-West Neo Medical center, School of Medicine, Kyunghee University)
Kim, Gou-Young (Department of Pathology, East-West Neo Medical center, School of Medicine, Kyunghee University)
Lim, Sung-Jig (Department of Pathology, East-West Neo Medical center, School of Medicine, Kyunghee University)
Kim, Hyun-Cheol (Department of Radiology, East-West Neo Medical center, School of Medicine, Kyunghee University)
Jeon, Seung-Hyun (Department of Urology, East-West Neo Medical center, School of Medicine, Kyunghee University)
Publication Information
The Korean Journal of Cytopathology / v.19, no.2, 2008 , pp. 194-199 More about this Journal
Abstract
The recent WHO classification has recognized mucinous tubular and spindle cell carcinoma (MTSCC) as a distinct entity of renal cell carcinoma, exhibiting a mixed pattern of tubules and a surrounding spindle cell proliferation within a myxoid stroma, with low-grade nuclear features. A 51-year-old woman had an incidentally discovered renal mass. Radiologic examination revealed a large, well defined mass in the lower pole of the right kidney; a right radical nephrectomy was performed. Imprint cytologic smears from fresh surgical specimens showed cellular, cohesive clusters with thick, broad trabecular arrangements and branching structures. On high power fields, the tumor was composed of round-to-oval low-grade nuclei with vesicular chromatin and small nucleoli. The tumor cells had indistinct borders and pale, eosinophilic cytoplasm, In some areas, round-to-elongated tubular structures and spindle cell patterns were noted. Chronic inflammatory cell infiltration was noted, along with a mucinous back-ground and occasional psammoma bodies. Neither significant cytologic atypia nor mitosis was seen.
Keywords
Kidney neoplasms; Carcinoma; Cytology; Kidney tubules;
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Times Cited By KSCI : 2  (Citation Analysis)
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