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Metastatic Melanoma Mimicking a Papillary Carcinoma of the Thyroid in Fine Needle Aspiration Cytology -A Case Report-  

Hong, Young-Ok (Department of Pathology, Ulsan University Hospital, Ulsan and Asan Medical Center)
Suh, Jae-Hee (Department of Pathology, University of Ulsan College of Medicine)
Cha, Hee-Jeong (Department of Pathology, University of Ulsan College of Medicine)
Choi, Hye-Jeong (Department of Pathology, University of Ulsan College of Medicine)
Kim, Young-Min (Department of Pathology, University of Ulsan College of Medicine)
Publication Information
The Korean Journal of Cytopathology / v.18, no.2, 2007 , pp. 161-164 More about this Journal
Abstract
Metastasis to the thyroid gland is very rare in clinical practice. We recently encountered a 65-year-old woman who presented with a large thyroid nodule that mimicked the cytologic features of a papillary thyroid carcinoma on fine needle aspiration biopsy (FNAB). Although initially diagnosed as a papillary thyroid carcinoma, a thorough clinical work-up revealed multiple lesions in the bones, liver, and nasal cavity, which were confirmed as metastases of a malignant melanoma. Despite a thorough physical examination, however, the primary skin lesion could not be identified. Although FNAB shows a high degree of accuracy in diagnosing primary thyroid tumors, it is less accurate in diagnosing metastases to the thyroid gland. A thorough clinical history with appropriate immunohistochemical staining assays is necessary for the accurate diagnosis of metastatic malignant melanoma.
Keywords
Malignant melanoma; Thyroid gland; Metastasis;
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Times Cited By KSCI : 1  (Citation Analysis)
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